Publications by authors named "Ahmed A Gaber"

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Pharmacophore-linked pyrazolo[3,4-d]pyrimidines as EGFR-TK inhibitors: Synthesis, anticancer evaluation, pharmacokinetics, and in silico mechanistic studies.
Ahmed A Gaber, Ahmed M El-Morsy, Farag F Sherbiny, Ashraf H Bayoumi, Kamal M El-Gamal

Arch Pharm (Weinheim)· March 2025

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Multi-target rational design and synthesis of novel diphenyl-tethered pyrazolopyrimidines targeting EGFR and topoisomerase II with potential DNA intercalation and apoptosis induction.
Ahmed A Gaber, Ayman Abo Elmaaty, Marwa Sharaky, Aliaa A Mosa, Abdullah Yahya Abdullah Alzahrani

Bioorg Chem· April 2024

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Design and synthesis of novel pyrazolopyrimidine candidates as promising EGFR-T790M inhibitors and apoptosis inducers.
Ahmed A Gaber, Marwa Sharaky, Ayman Abo Elmaaty, Mohamed M Hammouda, Ahmed Ae Mourad

Future Med Chem· October 2023

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Numerical analysis for tangent-hyperbolic micropolar nanofluid flow over an extending layer through a permeable medium.
Galal M Moatimid, Mona A A Mohamed, Ahmed A Gaber, Doaa M Mostafa

Sci Rep· August 2023

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Silver nanoparticles induced testicular damage targeting NQO1 and APE1 dysregulation, apoptosis via Bax/Bcl-2 pathway, fibrosis via TGF-β/α-SMA upregulation in rats.
Doaa H Assar, Abd-Allah A Mokhbatly, Mohamed F Abou ELazab, Emad W Ghazy, Ahmed A Gaber

Environ Sci Pollut Res Int· February 2023

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New [1,2,4]triazolo[4,3-c]quinazolines as intercalative Topo II inhibitors: Design, synthesis, biological evaluation, and in silico studies.
Ahmed A Gaber, Mohamed Sobhy, Abdallah Turky, Wagdy M Eldehna, Samiha A El-Sebaey

PLoS One· February 2023

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Discovery of new 1-pyrazolo[3,4-]pyrimidine derivatives as anticancer agents targeting EGFR and EGFR.
Ahmed A Gaber, Mohamed Sobhy, Abdallah Turky, Hanan Gaber Abdulwahab, Ahmed A Al-Karmalawy

J Enzyme Inhib Med Chem· December 2022

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Silver nanoparticles induced hepatoxicity via the apoptotic/antiapoptotic pathway with activation of TGFβ-1 and α-SMA triggered liver fibrosis in Sprague Dawley rats.
Doaa H Assar, Abd-Allah A Mokhbatly, Emad W Ghazy, Zizy I Elbialy, Ahmed A Gaber

Environ Sci Pollut Res Int· November 2022

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Design, synthesis and anticancer evaluation of 1H-pyrazolo[3,4-d]pyrimidine derivatives as potent EGFR and EGFR inhibitors and apoptosis inducers.
Ahmed A Gaber, Ashraf H Bayoumi, Ahmed M El-Morsy, Farag F Sherbiny, Ahmed B M Mehany

Bioorg Chem· October 2018

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Elevated serum Bcl-2 in children with temporal lobe epilepsy.
Ayman Kilany, Ehab R Abdel Raouf, Ahmed A Gaber, Taha Kamel Aloush, Hany A Aref

Seizure· May 2012

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DDB liver drug as a novel ionophore for potentiometric barium (II) membrane sensor.
Saad S M Hassan, Mohamed B Saleh, Ahmed A Abdel Gaber, Nahed A Abdel Kream

Talanta· January 2003

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