Publications by authors named "Aida Falgas"

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CAR-T cells targeting CCR9 and CD1a for the treatment of T cell acute lymphoblastic leukemia.
Néstor Tirado, Klaudyna Fidyt, María José Mansilla, Alba Garcia-Perez, Alba Martínez-Moreno

J Hematol Oncol· July 2025

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A TIM-3-Fc decoy secreted by engineered T cells improves CD19 CAR T-cell therapy in B-cell acute lymphoblastic leukemia.
Aïda Falgàs, Rodrigo Lázaro-Gorines, Samanta Romina Zanetti, Laura Rubio-Pérez, Alba Martínez-Moreno

Blood· May 2025

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CD22 CAR-T cells secreting CD19 T-cell engagers for improved control of B-cell acute lymphoblastic leukemia progression.
Javier Arroyo-Ródenas, Aida Falgas, Laura Díez-Alonso, Alba Martinez-Moreno, Heleia Roca-Ho

J Immunother Cancer· April 2025

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NG2 is a target gene of MLL-AF4 and underlies glucocorticoid resistance in MLLr B-ALL by regulating NR3C1 expression.
Belén Lopez-Millan, Alba Rubio-Gayarre, Meritxell Vinyoles, Juan L Trincado, Mario F Fraga

Blood· November 2024

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NSGS mice humanized with cord blood mononuclear cells show sustained and functional myeloid-lymphoid representation with limited graft-versus-host disease.
Carla Panisello, Rosario Aschero, Alba Martinez-Moreno, Heleia Roca Ho, Aida Falgas

J Immunother Cancer· October 2024

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Engineered T cells secreting anti-BCMA T cell engagers control multiple myeloma and promote immune memory in vivo.
Laura Díez-Alonso, Aïda Falgas, Javier Arroyo-Ródenas, Paola A Romencín, Alba Martínez

Sci Transl Med· February 2024

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T22-PE24-H6 Nanotoxin Selectively Kills CXCR4-High Expressing AML Patient Cells In Vitro and Potently Blocks Dissemination In Vivo.
Yáiza Núñez, Annabel Garcia-León, Aïda Falgàs, Naroa Serna, Laura Sánchez-García

Pharmaceutics· February 2023

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A diphtheria toxin-based nanoparticle achieves specific cytotoxic effect on CXCR4 lymphoma cells without toxicity in immunocompromised and immunocompetent mice.
Aïda Falgàs, Annabel Garcia-León, Yáiza Núñez, Naroa Serna, Laura Sánchez-Garcia

Biomed Pharmacother· June 2022

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Engineering non-antibody human proteins as efficient scaffolds for selective, receptor-targeted drug delivery.
Naroa Serna, Victor Pallarès, Ugutz Unzueta, Annabel Garcia-Leon, Eric Voltà-Durán

J Control Release· March 2022

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A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model.
Victor Pallarès, Ugutz Unzueta, Aïda Falgàs, Anna Aviñó, Yáiza Núñez

Biomaterials· January 2022

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Time-Prolonged Release of Tumor-Targeted Protein-MMAE Nanoconjugates from Implantable Hybrid Materials.
Naroa Serna, Aïda Falgàs, Annabel García-León, Ugutz Unzueta, Yáiza Núñez

Pharmaceutics· January 2022

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Selective delivery of T22-PE24-H6 to CXCR4 diffuse large B-cell lymphoma cells leads to wide therapeutic index in a disseminated mouse model.
Aïda Falgàs, Victor Pallarès, Naroa Serna, Laura Sánchez-García, Jorge Sierra

Theranostics· July 2021

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Antineoplastic effect of a diphtheria toxin-based nanoparticle targeting acute myeloid leukemia cells overexpressing CXCR4.
Victor Pallarès, Yáiza Núñez, Laura Sánchez-García, Aïda Falgàs, Naroa Serna

J Control Release· July 2021

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Biparatopic Protein Nanoparticles for the Precision Therapy of CXCR4 Cancers.
Olivia Cano-Garrido, Patricia Álamo, Laura Sánchez-García, Aïda Falgàs, Alejandro Sánchez-Chardi

Cancers (Basel)· June 2021

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Specific Cytotoxic Effect of an Auristatin Nanoconjugate Towards CXCR4 Diffuse Large B-Cell Lymphoma Cells.
Aïda Falgàs, Victor Pallarès, Ugutz Unzueta, Yáiza Núñez, Jorge Sierra

Int J Nanomedicine· March 2021

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Fluorescent Dye Labeling Changes the Biodistribution of Tumor-Targeted Nanoparticles.
Patricia Álamo, Victor Pallarès, María Virtudes Céspedes, Aïda Falgàs, Julieta M Sanchez

Pharmaceutics· October 2020

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An Auristatin nanoconjugate targeting CXCR4+ leukemic cells blocks acute myeloid leukemia dissemination.
Victor Pallarès, Ugutz Unzueta, Aïda Falgàs, Laura Sánchez-García, Naroa Serna

J Hematol Oncol· April 2020

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A CXCR4-targeted nanocarrier achieves highly selective tumor uptake in diffuse large B-cell lymphoma mouse models.
Aïda Falgàs, Victor Pallarès, Ugutz Unzueta, María Virtudes Céspedes, Irene Arroyo-Solera

Haematologica· March 2020

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Engineering Secretory Amyloids for Remote and Highly Selective Destruction of Metastatic Foci.
María Virtudes Céspedes, Olivia Cano-Garrido, Patricia Álamo, Rita Sala, Alberto Gallardo

Adv Mater· February 2020

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CXCR7 expression in diffuse large B-cell lymphoma identifies a subgroup of CXCR4+ patients with good prognosis.
María José Moreno, Alberto Gallardo, Silvana Novelli, Ana Mozos, Marc Aragó

PLoS One· December 2018

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Focal Adhesion Genes Refine the Intermediate-Risk Cytogenetic Classification of Acute Myeloid Leukemia.
Victor Pallarès, Montserrat Hoyos, M Carmen Chillón, Eva Barragán, M Isabel Prieto Conde

Cancers (Basel)· November 2018

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Selective CXCR4 Cancer Cell Targeting and Potent Antineoplastic Effect by a Nanostructured Version of Recombinant Ricin.
Raquel Díaz, Victor Pallarès, Olivia Cano-Garrido, Naroa Serna, Laura Sánchez-García

Small· June 2018

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