Publications by authors named "Aike A Kruize"

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Leflunomide/hydroxychloroquine combination therapy targets type I IFN-associated proteins in patients with Sjögren's syndrome that show potential to predict and monitor clinical response.
Safae Hamkour, Eefje Hm van der Heijden, Ana P Lopes, Sofie L M Blokland, Cornelis P J Bekker, Aike A Kruize

RMD Open· August 2023

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CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjögren's Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells.
Anneline C Hinrichs, Aike A Kruize, Floris P J G Lafeber, Helen L Leavis, Joel A G van Roon

Int J Mol Sci· July 2023

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Deciphering the role of cDC2s in Sjögren's syndrome: transcriptomic profile links altered antigen processes with IFN signature and autoimmunity.
Ana P Lopes, Maarten R Hillen, Anneline C Hinrichs, Sofie Lm Blokland, Cornelis Pj Bekker, Aike A Kruize

Ann Rheum Dis· March 2023

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In patients with primary Sjögren's syndrome innate-like MAIT cells display upregulated IL-7R, IFN-γ, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells.
Anneline C Hinrichs, Aike A Kruize, Helen L Leavis, Joel A G van Roon

Front Immunol· January 2023

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CCL5 Release by CCR9+ CD8 T Cells: A Potential Contributor to Immunopathology of Primary Sjögren's Syndrome.
Anneline C Hinrichs, Sofie L M Blokland, Aike A Kruize, Floris P J Lafeber, Helen L Leavis

Front Immunol· June 2022

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Transcriptome Analysis of CCR9+ T Helper Cells From Primary Sjögren's Syndrome Patients Identifies CCL5 as a Novel Effector Molecule.
Anneline C Hinrichs, Sofie L M Blokland, Ana P Lopes, Catharina G K Wichers, Aike A Kruize

Front Immunol· December 2021

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The Transcriptomic Profile of Monocytes from Patients With Sjögren's Syndrome Is Associated With Inflammatory Parameters and Is Mimicked by Circulating Mediators.
Ana P Lopes, Cornelis P J Bekker, Maarten R Hillen, Sofie L M Blokland, Anneline C Hinrichs, Aike A Kruize

Front Immunol· December 2021

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Influence of the age at diagnosis in the disease expression of primary Sjögren syndrome. Analysis of 12,753 patients from the Sjögren Big Data Consortium.
Soledad Retamozo, Nihan Acar-Denizli, Ildiko Fanny Horváth, Wan-Fai Ng, Astrid Rasmussen, Aike A Kruize

Clin Exp Rheumatol· December 2021

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Childhood-onset of primary Sjögren's syndrome: phenotypic characterization at diagnosis of 158 children.
Manuel Ramos-Casals, Nihan Acar-Denizli, Arjan Vissink, Pilar Brito-Zerón, Xiaomei Li, Aike A Kruize

Rheumatology (Oxford)· October 2021

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Therapeutic Recommendations for the Management of Older Adult Patients with Sjögren's Syndrome.
Soledad Retamozo, Chiara Baldini, Hendrika Bootsma, Salvatore De Vita, Thomas Dörner, Aike A Kruize

Drugs Aging· April 2021

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Plasmacytoid DCs From Patients With Sjögren's Syndrome Are Transcriptionally Primed for Enhanced Pro-inflammatory Cytokine Production.
Maarten R Hillen, Aridaman Pandit, Sofie L M Blokland, Sarita A Y Hartgring, Cornelis P J Bekker, Aike A Kruize

Front Immunol· November 2020

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MicroRNA-130a Contributes to Type-2 Classical DC-activation in Sjögren's Syndrome by Targeting Mitogen- and Stress-Activated Protein Kinase-1.
Ana P Lopes, Joel A G van Roon, Sofie L M Blokland, Maojie Wang, Eleni Chouri, Aike A Kruize

Front Immunol· October 2020

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Systemic phenotype related to primary Sjögren's syndrome in 279 patients carrying isolated anti-La/SSB antibodies.
Nihan Acar-Denizli, Ildiko-Fanny Horváth, Thomas Mandl, Roberta Priori, Arjan Vissink, Aike A Kruize

Clin Exp Rheumatol· October 2020

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Epidemiological profile and north-south gradient driving baseline systemic involvement of primary Sjögren's syndrome.
Pilar Brito-Zerón, Nihan Acar-Denizli, Wan-Fai Ng, Ildiko Fanny Horváth, Astrid Rasmussen, Aike A Kruize

Rheumatology (Oxford)· September 2020

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Leflunomide-hydroxychloroquine combination therapy in patients with primary Sjögren's syndrome (RepurpSS-I): a placebo-controlled, double-blinded, randomised clinical trial.
Eefje Hanna Martine van der Heijden, Sofie Liny Marie Blokland, Maarten Reinier Hillen, Ana Paula Pinheiro Lopes, Fréderique Marie van Vliet-Moret, Aike Albert Kruize

Lancet Rheumatol· May 2020

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Increased mTORC1 activation in salivary gland B cells and T cells from patients with Sjögren's syndrome: mTOR inhibition as a novel therapeutic strategy to halt immunopathology?
Sofie L M Blokland, Maarten R Hillen, Catharina G K Wichers, Maili Zimmermann, Aike A Kruize

RMD Open· April 2020

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Salivary gland secretome: a novel tool towards molecular stratification of patients with primary Sjögren's syndrome and non-autoimmune sicca.
Sofie L M Blokland, Maarten R Hillen, Fréderique M van Vliet-Moret, Angela Bikker, Wilco de Jager, Aike A Kruize

RMD Open· April 2020

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Efficacy and safety of topical and systemic medications: a systematic literature review informing the EULAR recommendations for the management of Sjögren's syndrome.
Pilar Brito-Zerón, Soledad Retamozo, Belchin Kostov, Chiara Baldini, Hendrika Bootsma, Aike A Kruize

RMD Open· April 2020

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Decreased circulating CXCR3 + CCR9+T helper cells are associated with elevated levels of their ligands CXCL10 and CCL25 in the salivary gland of patients with Sjögren's syndrome to facilitate their concerted migration.
Sofie L M Blokland, Andreas Kislat, Bernhard Homey, Glennda M Smithson, Aike A Kruize

Scand J Immunol· March 2020

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Epigenetically quantified immune cells in salivary glands of Sjögren's syndrome patients: a novel tool that detects robust correlations of T follicular helper cells with immunopathology.
Sofie L M Blokland, Fréderique M van Vliet-Moret, Maarten R Hillen, Aridaman Pandit, Roel Goldschmeding, Aike A Kruize

Rheumatology (Oxford)· February 2020

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EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies.
Manuel Ramos-Casals, Pilar Brito-Zerón, Stefano Bombardieri, Hendrika Bootsma, Salvatore De Vita, Aike A Kruize

Ann Rheum Dis· January 2020

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Dysregulated miRNome of plasmacytoid dendritic cells from patients with Sjögren's syndrome is associated with processes at the centre of their function.
Maarten R Hillen, Eleni Chouri, Maojie Wang, Sofie L M Blokland, Sarita A Y Hartgring, Aike A Kruize

Rheumatology (Oxford)· December 2019

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Increased expression of Fas on group 2 and 3 innate lymphoid cells is associated with an interferon signature in systemic lupus erythematosus and Sjögren's syndrome.
Sofie L M Blokland, Lucas L van den Hoogen, Emmerik F A Leijten, Sarita A Y Hartgring, Ruth Fritsch, Aike A Kruize

Rheumatology (Oxford)· October 2019

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Additive immunosuppressive effect of leflunomide and hydroxychloroquine supports rationale for combination therapy for Sjögren's syndrome.
Eefje Hm van der Heijden, Sarita Ay Hartgring, Aike A Kruize, Timothy Rdj Radstake, Joel Ag van Roon

Expert Rev Clin Immunol· July 2019

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How immunological profile drives clinical phenotype of primary Sjögren's syndrome at diagnosis: analysis of 10,500 patients (Sjögren Big Data Project).
Pilar Brito-Zerón, Nihan Acar-Denizli, Wan-Fai Ng, Margit Zeher, Astrid Rasmussen, Aike A Kruize

Clin Exp Rheumatol· November 2018

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