Publications by authors named "Aileen Houston"

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The complex roles of IL-36 and IL-38 in cancer: friends or foes?
Méabh Finucane, Elizabeth Brint, Aileen Houston

Oncogene· April 2025

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Interplay between microbial-derived GABA and host GABA receptor signaling collectively influence the tumorigenic function of GABA in colon cancer.
Jonathan M Keane, Philana Fernandes, Florian Kratz, Grace O'Callaghan, Cormac G M Gahan, Aileen Houston

Pharmacol Res Perspect· August 2024

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IL-36 expression is increased in NSCLC with IL-36 stimulation of lung cancer cells promoting a pro-tumorigenic phenotype.
Kevin James Baker, Emily Buskiewicz, Méabh Finucane, Adeleine Chelliah, Louise Burke, Aileen Houston

Cytokine· May 2023

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Transcriptomic and functional analyses reveal a tumour-promoting role for the IL-36 receptor in colon cancer and crosstalk between IL-36 signalling and the IL-17/ IL-23 axis.
Kevin James Baker, Elizabeth Brint, Aileen Houston

Br J Cancer· March 2023

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Dietary-Induced Bacterial Metabolites Reduce Inflammation and Inflammation-Associated Cancer via Vitamin D Pathway.
Caitlin O'Mahony, Adam Clooney, Siobhan F Clarke, Mònica Aguilera, Aisling Gavin, Aileen Houston

Int J Mol Sci· January 2023

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Defining optimal parameters to maximize the effect of electrochemotherapy on lung cancer cells whilst preserving the integrity of immune cells.
Maura B Bendix, Aileen Houston, Patrick F Forde, Elizabeth Brint

Bioelectrochemistry· December 2022

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DNA sensor-associated type I interferon signaling is increased in ulcerative colitis and induces JAK-dependent inflammatory cell death in colonic organoids.
Peter Flood, Aine Fanning, Jerzy A Woznicki, Tadhg Crowley, Andrea Christopher, Aileen Houston

Am J Physiol Gastrointest Liver Physiol· November 2022

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Electrochemotherapy and immune interactions; A boost to the system?
Maura B Bendix, Aileen Houston, Patrick F Forde, Elizabeth Brint

Eur J Surg Oncol· September 2022

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IL-36 signalling enhances a pro-tumorigenic phenotype in colon cancer cells with cancer cell growth restricted by administration of the IL-36R antagonist.
Kevin Baker, Charlotte O'Donnell, Maura Bendix, Samuel Keogh, James Byrne, Aileen Houston

Oncogene· May 2022

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IL-36 cytokines in inflammatory and malignant diseases: not the new kid on the block anymore.
James Byrne, Kevin Baker, Aileen Houston, Elizabeth Brint

Cell Mol Life Sci· September 2021

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IL-1 Family Members in Cancer; Two Sides to Every Story.
Kevin J Baker, Aileen Houston, Elizabeth Brint

Front Immunol· November 2020

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The COX-2 inhibitor NS398 selectively sensitizes hypoxic HeLa cells to ionising radiation by mechanisms both dependent and independent of COX-2.
Shailendra Anoopkumar-Dukie, Tom Conere, Aileen Houston, Liam King, David Christie

Prostaglandins Other Lipid Mediat· June 2020

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Engagement of Fas differentially regulates the production of LPS-induced proinflammatory cytokines and type I interferons.
Kiva Brennan, Caitriona Lyons, Philana Fernandes, Sarah Doyle, Aileen Houston

FEBS J· February 2019

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A Bifidobacterial pilus-associated protein promotes colonic epithelial proliferation.
Mary O'Connell Motherway, Aileen Houston, Grace O'Callaghan, Justus Reunanen, Frances O'Brien

Mol Microbiol· January 2019

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Pregnancy-specific glycoprotein expression in normal gastrointestinal tract and in tumors detected with novel monoclonal antibodies.
Aileen Houston, John M Williams, Tihana Lenac Rovis, Daniel K Shanley, Ronan T O'Riordan

MAbs· December 2016

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Mesenchymal stromal cells (MSCs) and colorectal cancer: a troublesome twosome for the anti-tumour immune response?
Grace O'Malley, Madelon Heijltjes, Aileen M Houston, Sweta Rani, Thomas Ritter

Oncotarget· September 2016

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Engagement of Fas on Macrophages Modulates Poly I:C induced cytokine production with specific enhancement of IP-10.
Caitriona Lyons, Philana Fernandes, Liam J Fanning, Aileen Houston, Elizabeth Brint

PLoS One· April 2016

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An antitumorigenic role for the IL-33 receptor, ST2L, in colon cancer.
Charlotte O'Donnell, Amr Mahmoud, Jonathan Keane, Carola Murphy, Declan White, Aileen Houston

Br J Cancer· January 2016

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Intestinal expression of Fas and Fas ligand is upregulated by bacterial signaling through TLR4 and TLR5, with activation of Fas modulating intestinal TLR-mediated inflammation.
Philana Fernandes, Charlotte O'Donnell, Caitriona Lyons, Jonathan Keane, Tim Regan, Aileen Houston

J Immunol· December 2014

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Identification of TLR10 as a key mediator of the inflammatory response to Listeria monocytogenes in intestinal epithelial cells and macrophages.
Tim Regan, Ken Nally, Ruaidhri Carmody, Aileen Houston, Fergus Shanahan

J Immunol· December 2013

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Life in the Fas lane: differential outcomes of Fas signaling.
Elizabeth Brint, Grace O'Callaghan, Aileen Houston

Cell Mol Life Sci· November 2013

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Targeting the EP1 receptor reduces Fas ligand expression and increases the antitumor immune response in an in vivo model of colon cancer.
Grace O'Callaghan, Aideen Ryan, Peter Neary, Caitlin O'Mahony, Fergus Shanahan, Aileen Houston

Int J Cancer· August 2013

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Loss of p38δ mitogen-activated protein kinase expression promotes oesophageal squamous cell carcinoma proliferation, migration and anchorage-independent growth.
Carol O'Callaghan, Liam J Fanning, Aileen Houston, Orla P Barry

Int J Oncol· August 2013

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Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor.
Mary O'Connell Motherway, Aldert Zomer, Sinead C Leahy, Justus Reunanen, Francesca Bottacini, Aileen M Houston

Proc Natl Acad Sci U S A· July 2011

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The "Fas counterattack" is not an active mode of tumor immune evasion in colorectal cancer with high-level microsatellite instability.
Aileen M Houston, Julie M Michael-Robinson, Michael D Walsh, Margaret C Cummings, Aideen E Ryan

Hum Pathol· February 2008

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