Publications by authors named "Aileen Rubio"

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Efficacy of SPR720 in murine models of non-tuberculous mycobacterial pulmonary infection.
Nicole Cotroneo, Suzanne S Stokes, Michael J Pucci, Aileen Rubio, Kamal A Hamed

J Antimicrob Chemother· April 2024

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and Characterization of Tebipenem, an Oral Carbapenem.
Nicole Cotroneo, Aileen Rubio, Ian A Critchley, Chris Pillar, Michael J Pucci

Antimicrob Agents Chemother· July 2020

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Potentiation of Antibiotics against Gram-Negative Bacteria by Polymyxin B Analogue SPR741 from Unique Perturbation of the Outer Membrane.
Shawn French, Maya Farha, Michael J Ellis, Zaid Sameer, Jean-Philippe Côté, Aileen Rubio

ACS Infect Dis· June 2020

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Evaluation of Antimicrobial Effects of a New Polymyxin Molecule (SPR741) When Tested in Combination with a Series of β-Lactam Agents Against a Challenge Set of Gram-Negative Pathogens.
Rodrigo E Mendes, Paul R Rhomberg, Troy Lister, Nicole Cotroneo, Aileen Rubio

Microb Drug Resist· April 2020

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Antimicrobial Activity Evaluation of Tebipenem (SPR859), an Orally Available Carbapenem, against a Global Set of Enterobacteriaceae Isolates, Including a Challenge Set of Organisms.
S J Ryan Arends, Paul R Rhomberg, Nicole Cotroneo, Aileen Rubio, Robert K Flamm

Antimicrob Agents Chemother· June 2019

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Activity of Tebipenem (SPR859) against Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria.
Evelyne Lacasse, Eric Brouillette, Audrey Larose, Thomas R Parr, Aileen Rubio

Antimicrob Agents Chemother· April 2019

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Susceptibility Testing of a Novel Benzimidazole, SPR719, against Nontuberculous Mycobacteria.
Barbara A Brown-Elliott, Aileen Rubio, Richard J Wallace

Antimicrob Agents Chemother· November 2018

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Shared Platform for Antibiotic Research and Knowledge: A Collaborative Tool to SPARK Antibiotic Discovery.
Joe Thomas, Marc Navre, Aileen Rubio, Allan Coukell

ACS Infect Dis· November 2018

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Characterization of SPR994, an Orally Available Carbapenem, with Activity Comparable to Intravenously Administered Carbapenems.
Aileen Rubio, Michael J Pucci, Akash Jain

ACS Infect Dis· October 2018

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Bioanalysis of Pseudomonas aeruginosa alkyl quinolone signalling molecules in infected mouse tissue using LC-MS/MS; and its application to a pharmacodynamic evaluation of MvfR inhibition.
Paul Turnpenny, Anthony Padfield, Patrick Barton, Joanne Teague, Laurence G Rahme, Aileen Rubio

J Pharm Biomed Anal· May 2017

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Dysregulation of mprF and dltABCD expression among daptomycin-non-susceptible MRSA clinical isolates.
Arnold S Bayer, Nagendra N Mishra, Ambrose L Cheung, Aileen Rubio, Soo-Jin Yang

J Antimicrob Chemother· August 2016

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Impact of daptomycin resistance on Staphylococcus aureus virulence.
David R Cameron, Lawrence I Mortin, Aileen Rubio, Eleftherios Mylonakis, Robert C Moellering

Virulence· January 2016

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Frequency and Distribution of Single-Nucleotide Polymorphisms within mprF in Methicillin-Resistant Staphylococcus aureus Clinical Isolates and Their Role in Cross-Resistance to Daptomycin and Host Defense Antimicrobial Peptides.
Arnold S Bayer, Nagendra N Mishra, Liang Chen, Barry N Kreiswirth, Aileen Rubio

Antimicrob Agents Chemother· August 2015

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Causal role of single nucleotide polymorphisms within the mprF gene of Staphylococcus aureus in daptomycin resistance.
Soo-Jin Yang, Nagendra N Mishra, Aileen Rubio, Arnold S Bayer

Antimicrob Agents Chemother· November 2013

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Additional routes to Staphylococcus aureus daptomycin resistance as revealed by comparative genome sequencing, transcriptional profiling, and phenotypic studies.
Yang Song, Aileen Rubio, Radheshyam K Jayaswal, Jared A Silverman, Brian J Wilkinson

PLoS One· September 2013

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Differential Adaptations of Methicillin-Resistant Staphylococcus aureus to Serial In Vitro Passage in Daptomycin: Evolution of Daptomycin Resistance and Role of Membrane Carotenoid Content and Fluidity.
Nagendra N Mishra, Aileen Rubio, Cynthia C Nast, Arnold S Bayer

Int J Microbiol· September 2012

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Whole genome characterization of the mechanisms of daptomycin resistance in clinical and laboratory derived isolates of Staphylococcus aureus.
Anton Y Peleg, Spiros Miyakis, Doyle V Ward, Ashlee M Earl, Aileen Rubio

PLoS One· May 2012

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LC-MS/MS characterization of phospholipid content in daptomycin-susceptible and -resistant isolates of Staphylococcus aureus with mutations in mprF.
Aileen Rubio, Jeff Moore, Mustafa Varoglu, Mary Conrad, Min Chu

Mol Membr Biol· February 2012

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VraSR two-component regulatory system contributes to mprF-mediated decreased susceptibility to daptomycin in in vivo-selected clinical strains of methicillin-resistant Staphylococcus aureus.
Shrenik Mehta, Arabela X Cuirolo, Konrad B Plata, Sarah Riosa, Jared A Silverman, Aileen Rubio

Antimicrob Agents Chemother· January 2012

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In vitro cross-resistance to daptomycin and host defense cationic antimicrobial peptides in clinical methicillin-resistant Staphylococcus aureus isolates.
Nagendra N Mishra, James McKinnell, Michael R Yeaman, Aileen Rubio, Cynthia C Nast

Antimicrob Agents Chemother· September 2011

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Regulation of mprF by antisense RNA restores daptomycin susceptibility to daptomycin-resistant isolates of Staphylococcus aureus.
Aileen Rubio, Mary Conrad, Robert J Haselbeck, Kedar G C, Vickie Brown-Driver

Antimicrob Agents Chemother· January 2011

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Analysis of cell membrane characteristics of in vitro-selected daptomycin-resistant strains of methicillin-resistant Staphylococcus aureus.
Nagendra N Mishra, Soo-Jin Yang, Ayumi Sawa, Aileen Rubio, Cynthia C Nast

Antimicrob Agents Chemother· June 2009

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Characterization of a daptomycin-nonsusceptible vancomycin-intermediate Staphylococcus aureus strain in a patient with endocarditis.
Kathleen Julian, Klaudia Kosowska-Shick, Cynthia Whitener, Martin Roos, Harald Labischinski, Aileen Rubio

Antimicrob Agents Chemother· September 2007

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Engulfment-regulated proteolysis of SpoIIQ: evidence that dual checkpoints control sigma activity.
Xin Jiang, Aileen Rubio, Shinobu Chiba, Kit Pogliano

Mol Microbiol· October 2005

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Localization of translocation complex components in Bacillus subtilis: enrichment of the signal recognition particle receptor at early sporulation septa.
Aileen Rubio, Xin Jiang, Kit Pogliano

J Bacteriol· July 2005

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