Publications by authors named "Ailing Scott"

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YAP1 Depletion Enhances TAZ and its Complexation with TEAD4 and AP-1 Heterodimer C-JUN/FOSB to Promote Gastric Cancer Progression and Metastases.
Jingjing Wu, Dipti Athavale, Curt Balch, Junsong Zhao, Gengyi Zou, Ailing Scott

bioRxiv· November 2025

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KAP1 promotes gastric adenocarcinoma progression by activating Hippo/YAP1 signaling via binding to HNRNPAB.
Shumei Song, Yibo Fan, Gengyi Zou, Longfei Huo, Janani Kumar, Ailing W Scott

Cancer Lett· July 2025

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HSP90 inhibitor AUY922 suppresses tumor growth and modulates immune response through YAP1-TEAD pathway inhibition in gastric cancer.
Katsuhiro Yoshimura, Gengyi Zou, Yibo Fan, Kohei Yamashita, Lingzhi Wang, Ailing W Scott

Cancer Lett· February 2025

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Galectin-3 Cooperates with CD47 to Suppress Phagocytosis and T-cell Immunity in Gastric Cancer Peritoneal Metastases.
Yibo Fan, Shumei Song, Yuan Li, Shilpa S Dhar, Jiankang Jin, Ailing W Scott

Cancer Res· November 2023

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Evolution of immune and stromal cell states and ecotypes during gastric adenocarcinoma progression.
Ruiping Wang, Shumei Song, Jiangjiang Qin, Katsuhiro Yoshimura, Fuduan Peng, Ailing W Scott

Cancer Cell· August 2023

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Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment.
Yibo Fan, Yuan Li, Xiaodan Yao, Jiangkang Jin, Ailing Scott

Gut· April 2023

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A new intronic quantitative PCR method led to the discovery of transformation from human ascites to murine malignancy in a mouse model.
Jiankang Jin, Longfei Huo, Yibo Fan, Ruiping Wang, Ailing W Scott

Front Oncol· February 2023

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GRK3 is a poor prognosticator and serves as a therapeutic target in advanced gastric adenocarcinoma.
Yuan Li, Yibo Fan, Jinbang Xu, Longfei Huo, Ailing W Scott

J Exp Clin Cancer Res· August 2022

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Loss of ARID1A activates mTOR signaling and SOX9 in gastric adenocarcinoma-rationale for targeting deficiency.
Xiaochuan Dong, Shumei Song, Yuan Li, Yibo Fan, Lulu Wang, Ailing Scott

Gut· March 2022

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Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma.
Shumei Song, Qiongrong Chen, Yuan Li, Guang Lei, Ailing Scott

Gut· December 2021

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Patient-derived cell lines and orthotopic mouse model of peritoneal carcinomatosis recapitulate molecular and phenotypic features of human gastric adenocarcinoma.
Shumei Song, Yan Xu, Longfei Huo, Shuangtao Zhao, Ruiping Wang, Ailing W Scott

J Exp Clin Cancer Res· June 2021

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Correction to: LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma.
Yan Xu, Yuan Li, Jiankang Jin, Guangchun Han, Chengcao Sun, Ailing Scott

Mol Cancer· March 2021

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YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition.
Jaffer A Ajani, Yan Xu, Longfei Huo, Ruiping Wang, Yuan Li, Ailing Scott

Gut· January 2021

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LncRNA PVT1 Is a Poor Prognosticator and Can Be Targeted by PVT1 Antisense Oligos in Gastric Adenocarcinoma.
Yuan Li, Shumei Song, Melissa Pool Pizzi, Guangchun Han, Ailing W Scott

Cancers (Basel)· October 2020

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An improved strategy for CRISPR/Cas9 gene knockout and subsequent wildtype and mutant gene rescue.
Jiankang Jin, Yan Xu, Longfei Huo, Lang Ma, Ailing W Scott

PLoS One· June 2020

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Targeting Hippo coactivator YAP1 through BET bromodomain inhibition in esophageal adenocarcinoma.
Shumei Song, Yuan Li, Yan Xu, Lang Ma, Melissa Pool Pizzi, Ailing W Scott

Mol Oncol· June 2020

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PPARδ Interacts with the Hippo Coactivator YAP1 to Promote SOX9 Expression and Gastric Cancer Progression.
Shumei Song, Zhenning Wang, Yuan Li, Lang Ma, Jiankang Jin, Ailing W Scott

Mol Cancer Res· March 2020

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Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response.
Ruiping Wang, Shumei Song, Kazuto Harada, Fatemeh Ghazanfari Amlashi, Brian Badgwell, Ailing Scott

Gut· January 2020

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LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma.
Yan Xu, Yuan Li, Jiankang Jin, Guangchun Han, Chengcao Sun, Ailing Scott

Mol Cancer· October 2019

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YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer - Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer.
Fan Li, Yan Xu, Bovey Liu, Pankaj Kumar Singh, Wei Zhao, Ailing W Scott

Clin Cancer Res· April 2019

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A Novel YAP1 Inhibitor Targets CSC-Enriched Radiation-Resistant Cells and Exerts Strong Antitumor Activity in Esophageal Adenocarcinoma.
Shumei Song, Min Xie, Ailing W Scott, Jiankang Jin, Lang Ma

Mol Cancer Ther· February 2018

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Galectin-3 expression is prognostic in diffuse type gastric adenocarcinoma, confers aggressive phenotype, and can be targeted by YAP1/BET inhibitors.
Jaffer A Ajani, Jeannelyn S Estrella, Qiongrong Chen, Arlene M Correa, Lang Ma, Ailing W Scott

Br J Cancer· January 2018

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Nuclear expression of Gli-1 is predictive of pathologic complete response to chemoradiation in trimodality treated oesophageal cancer patients.
Roopma Wadhwa, Xuemei Wang, Veerabhadran Baladandayuthapani, Bin Liu, Hironori Shiozaki, Ailing W Scott

Br J Cancer· August 2017

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ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer.
Qiongrong Chen, Shumei Song, Shaozhong Wei, Bin Liu, Soichiro Honjo, Ailing Scott

Oncotarget· September 2015

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The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal Cancer.
Shumei Song, Soichiro Honjo, Jiankang Jin, Shih-Shin Chang, Ailing W Scott

Clin Cancer Res· June 2015

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