Publications by authors named "Ainhoa Mielgo"

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Macrophages suppress CD8 + T cell cytotoxic function in triple negative breast cancer via VISTA.
Maidinaimu Abudula, Yuliana Astuti, Meirion Raymant, Vijay Sharma, Michael C Schmid, Ainhoa Mielgo

Br J Cancer· July 2025

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Neoadjuvant treatment versus upfront surgery in borderline resectable and resectable pancreatic ductal adenocarcinoma: meta-analysis.
Luke D Dickerson, Jayden Gittens, Chris Brunning, Richard Jackson, Michael C Schmid, Ainhoa Mielgo

BJS Open· March 2025

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Expression of versican isoforms V0/V1 by pancreatic cancer associated fibroblasts increases fibroblast proliferation.
Sufyan Elhashani, Mark Glenn, Meirion Raymant, Michael C Schmid, Ainhoa Mielgo

Pancreatology· August 2024

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Inhibition of insulin-like growth factors increases production of CXCL9/10 by macrophages and fibroblasts and facilitates CD8 cytotoxic T cell recruitment to pancreatic tumours.
Patrick Freeman, Gaia Bellomo, Lucy Ireland, Maidinaimu Abudula, Teifion Luckett, Ainhoa Mielgo

Front Immunol· August 2024

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Efferocytosis reprograms the tumor microenvironment to promote pancreatic cancer liver metastasis.
Yuliana Astuti, Meirion Raymant, Valeria Quaranta, Kim Clarke, Maidinaimu Abudula, Ainhoa Mielgo

Nat Cancer· May 2024

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Author Correction: Efferocytosis reprograms the tumor microenvironment to promote pancreatic cancer liver metastasis.
Yuliana Astuti, Meirion Raymant, Valeria Quaranta, Kim Clarke, Maidinaimu Abudula, Ainhoa Mielgo

Nat Cancer· May 2024

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Macrophage-fibroblast JAK/STAT dependent crosstalk promotes liver metastatic outgrowth in pancreatic cancer.
Meirion Raymant, Yuliana Astuti, Laura Alvaro-Espinosa, Daniel Green, Valeria Quaranta, Ainhoa Mielgo

Nat Commun· April 2024

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Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis.
Teifion Luckett, Maidinaimu Abudula, Lucy Ireland, Mark Glenn, Gaia Bellomo, Ainhoa Mielgo

Cancer Res· February 2024

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PINCER (A Platform Study for solId orgaN CancERs): an agile pan-network platform study to deliver high-quality translational research.
Robert P Jones, Ainhoa Mielgo, Michael Schmid, Danielle Bury, Timothy Andrews

Br J Surg· August 2023

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Chemotherapy-induced infiltration of neutrophils promotes pancreatic cancer metastasis via Gas6/AXL signalling axis.
Gaia Bellomo, Carolyn Rainer, Valeria Quaranta, Yuliana Astuti, Meirion Raymant, Ainhoa Mielgo

Gut· November 2022

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Blockade of Stromal Gas6 Alters Cancer Cell Plasticity, Activates NK Cells, and Inhibits Pancreatic Cancer Metastasis.
Lucy Ireland, Teifion Luckett, Michael C Schmid, Ainhoa Mielgo

Front Immunol· March 2021

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Cancer-Associated Fibroblast Mediated Inhibition of CD8+ Cytotoxic T Cell Accumulation in Tumours: Mechanisms and Therapeutic Opportunities.
Patrick Freeman, Ainhoa Mielgo

Cancers (Basel)· September 2020

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Liver Tropism in Cancer: The Hepatic Metastatic Niche.
Ainhoa Mielgo, Michael C Schmid

Cold Spring Harb Perspect Med· March 2020

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Blockade of MIF-CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma.
Carlos R Figueiredo, Ricardo A Azevedo, Sasha Mousdell, Pedro T Resende-Lara, Lucy Ireland, Ainhoa Mielgo

Front Immunol· July 2019

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Macrophages and Fibroblasts, Key Players in Cancer Chemoresistance.
Lucy V Ireland, Ainhoa Mielgo

Front Cell Dev Biol· October 2018

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Macrophage-Derived Granulin Drives Resistance to Immune Checkpoint Inhibition in Metastatic Pancreatic Cancer.
Valeria Quaranta, Carolyn Rainer, Sebastian R Nielsen, Meirion L Raymant, Muhammad S Ahmed, Ainhoa Mielgo

Cancer Res· August 2018

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Blockade of insulin-like growth factors increases efficacy of paclitaxel in metastatic breast cancer.
Lucy Ireland, Almudena Santos, Fiona Campbell, Carlos Figueiredo, Dean Hammond, Ainhoa Mielgo

Oncogene· April 2018

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Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors.
Lucy Ireland, Almudena Santos, Muhammad S Ahmed, Carolyn Rainer, Sebastian R Nielsen, Ainhoa Mielgo

Cancer Res· December 2016

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Corrigendum: Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis.
Sebastian R Nielsen, Valeria Quaranta, Andrea Linford, Perpetua Emeagi, Carolyn Rainer, Ainhoa Mielgo

Nat Cell Biol· June 2016

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Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis.
Sebastian R Nielsen, Valeria Quaranta, Andrea Linford, Perpetua Emeagi, Carolyn Rainer, Ainhoa Mielgo

Nat Cell Biol· May 2016

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Kinase-independent role for CRAF-driving tumour radioresistance via CHK2.
Sunil J Advani, Maria Fernanda Camargo, Laetitia Seguin, Ainhoa Mielgo, Sudarshan Anand

Nat Commun· September 2015

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An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
Laetitia Seguin, Shumei Kato, Aleksandra Franovic, M Fernanda Camargo, Jacqueline Lesperance, Ainhoa Mielgo

Nat Cell Biol· May 2014

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Impact of tumour associated macrophages in pancreatic cancer.
Ainhoa Mielgo, Michael C Schmid

BMB Rep· March 2013

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Caspase-8 isoform 6 promotes death effector filament formation independent of microtubules.
Robert T Yuan, Shanique Young, Jesse Liang, Michael C Schmid, Ainhoa Mielgo

Apoptosis· March 2012

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A MEK-independent role for CRAF in mitosis and tumor progression.
Ainhoa Mielgo, Laetitia Seguin, Miller Huang, Maria Fernanda Camargo, Sudarshan Anand

Nat Med· November 2011

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