Publications by authors named "Aiting Yang"

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Laminin γ2 accelerates non-alcoholic fatty liver disease progression by enhancing lipid accumulation and fibrogenesis in hepatocytes.
Hui Chen, Guanggang Meng, Aiting Yang

Biochem Biophys Res Commun· September 2025

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Targeting LOXL1-expressing Hepatic Stellate Cell Inhibits Fibrogenesis and Sinusoid Angiogenesis via LOXL1/RUNX1/VEGFA Axis During Progression of Liver Fibrosis.
Xuzhen Yan, Qi Han, Yiwen Wang, Weiyu Li, Ning Zhang, Aiting Yang

Cell Mol Gastroenterol Hepatol· September 2025

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Fibulin-1 deficiency alleviates liver fibrosis by inhibiting hepatic stellate cell activation via the p38 MAPK pathway.
Wenshan Zhao, Jingyu Zhang, Qingdong Guo, Qi Wang, Hong Zhao, Aiting Yang

Cell Mol Life Sci· May 2025

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ITGA8 deficiency in hepatic stellate cells attenuates CCl-Induced liver fibrosis via suppression of COL11A1.
Xuzhen Yan, Qi Han, Wenyue Wu, Hong Li, Wen Zhang, Aiting Yang

Biochem Biophys Res Commun· April 2025

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Hepatic stellate cell-derived microfibrillar-associated protein 2 prevents liver fibrosis by regulating extracellular matrix and inflammation.
Wen Zhang, Wenyue Wu, Ning Zhang, Hong Li, Yameng Sun, Aiting Yang

Theranostics· April 2025

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Crosstalk of lysyl oxidase-like 1 and lysyl oxidase prolongs their half-lives and regulates liver fibrosis through Notch signal.
Ning Zhang, Aiting Yang, Wen Zhang, Hong Li, Anjian Xu

Hepatol Commun· April 2024

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Targeting thrombospondin-2 retards liver fibrosis by inhibiting TLR4-FAK/TGF-β signaling.
Ning Zhang, Xiaoning Wu, Wen Zhang, Yameng Sun, Xuzhen Yan, Aiting Yang

JHEP Rep· March 2024

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Selective inhibition of hepatic stellate cell and fibroblast-derived LOXL1 attenuates BDL- and -induced cholestatic liver fibrosis.
Xuzhen Yan, Ning Zhang, Luyang Wei, Wen Zhang, Tao Huang, Aiting Yang

Am J Physiol Gastrointest Liver Physiol· December 2023

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Aryl hydrocarbon receptor attenuates cholestatic liver injury by regulating bile acid metabolism.
Qi Han, Xuzhen Yan, Likai Wang, Ning Zhang, Wen Zhang, Aiting Yang

Biochem Biophys Res Commun· November 2023

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Matrisome gene-based subclassification of patients with liver fibrosis identifies clinical and molecular heterogeneities.
Wei Chen, Yameng Sun, Shuyan Chen, Xiaodong Ge, Wen Zhang, Aiting Yang

Hepatology· October 2023

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Inhibition of phospholipase D1 ameliorates hepatocyte steatosis and non-alcoholic fatty liver disease.
Huan Wang, Yushang Zhao, Yuhualei Pan, Aiting Yang, Changying Li

JHEP Rep· June 2023

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Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis.
Ai-Ting Yang, Yong-Ook Kim, Xu-Zhen Yan, Hiroyuki Abe, Misbah Aslam

Cell Mol Gastroenterol Hepatol· March 2023

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Overexpression of Hepcidin Alleviates Steatohepatitis and Fibrosis in a Diet-induced Nonalcoholic Steatohepatitis.
Hui Chen, Wenshan Zhao, Xuzhen Yan, Tao Huang, Aiting Yang

J Clin Transl Hepatol· August 2022

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Hepatic stellate cells-specific LOXL1 deficiency abrogates hepatic inflammation, fibrosis, and corrects lipid metabolic abnormalities in non-obese NASH mice.
Aiting Yang, Xuzhen Yan, Xu Fan, Yiwen Shi, Tao Huang

Hepatol Int· October 2021

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Selective depletion of hepatic stellate cells-specific LOXL1 alleviates liver fibrosis.
Aiting Yang, Xuzhen Yan, Hufeng Xu, Xu Fan, Mengyang Zhang

FASEB J· October 2021

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Lysyl Oxidase (LOX) Family Members: Rationale and Their Potential as Therapeutic Targets for Liver Fibrosis.
Wei Chen, Aiting Yang, Jidong Jia, Yury V Popov, Detlef Schuppan

Hepatology· August 2020

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miRNA-150-5p promotes hepatic stellate cell proliferation and sensitizes hepatocyte apoptosis during liver fibrosis.
Wei Chen, Xuzhen Yan, Aiting Yang, Anjian Xu, Tao Huang

Epigenomics· January 2020

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Dynamics of elastin in liver fibrosis: Accumulates late during progression and degrades slowly in regression.
Wei Chen, Xuzhen Yan, Anjian Xu, Yameng Sun, Bingqiong Wang, Aiting Yang

J Cell Physiol· December 2019

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α-Mannosyl-Functionalized Cationic Nanohydrogel Particles for Targeted Gene Knockdown in Immunosuppressive Macrophages.
Nadine Leber, Leonard Kaps, Aiting Yang, Misbah Aslam, Mariacristina Giardino

Macromol Biosci· July 2019

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Multitranscriptome analyses reveal prioritized genes specifically associated with liver fibrosis progression independent of etiology.
Wei Chen, Xiaoning Wu, Xuzhen Yan, Anjian Xu, Aiting Yang

Am J Physiol Gastrointest Liver Physiol· June 2019

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Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking.
Wenshan Zhao, Aiting Yang, Wei Chen, Ping Wang, Tianhui Liu

Biochim Biophys Acta Mol Basis Dis· April 2018

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PHP14 regulates hepatic stellate cells migration in liver fibrosis via mediating TGF-β1 signaling to PI3Kγ/AKT/Rac1 pathway.
Anjian Xu, Yanmeng Li, Wenshan Zhao, Fei Hou, Xiaojin Li, Aiting Yang

J Mol Med (Berl)· February 2018

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Integrated analysis of microRNA and gene expression profiles reveals a functional regulatory module associated with liver fibrosis.
Wei Chen, Wenshan Zhao, Aiting Yang, Anjian Xu, Huan Wang

Gene· December 2017

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Inhibitory effects of HNF4α on migration/maltransformation of hepatic progenitors: HNF4α-overexpressing hepatic progenitors for liver repopulation.
Ping Wang, Min Cong, Tianhui Liu, Hufeng Xu, Lin Wang, Aiting Yang

Stem Cell Res Ther· August 2017

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The Characteristics Variation of Hepatic Progenitors after TGF-β1-Induced Transition and EGF-Induced Reversion.
Ping Wang, Min Cong, Tianhui Liu, Aiting Yang, Guangyong Sun

Stem Cells Int· March 2016

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