Publications by authors named "Aiwu He"

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Durvalumab plus chemotherapy in advanced biliary tract cancer: 3-year overall survival update from the phase III TOPAZ-1 study.
Do-Youn Oh, Aiwu Ruth He, Shukui Qin, Li-Tzong Chen, Takuji Okusaka

J Hepatol· November 2025

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A Phase I Dose-Escalation Study of Polyphenon E in Liver Cirrhosis: Evaluation of Safety and Effect on Liver γ-OHPdG Levels.
Aiwu Ruth He, Coleman I Smith, Marcia Cruz-Correa, Richik Chakraborty, Shuwei Zhang, Shengmin Sang, Guang Cheng, Stephen S Hecht, Masha Kocherginsky, Tia Schering

Cancer Prev Res (Phila)· October 2025

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Serum Proteomic Profile Based on the TGF-β Pathway Stratifies Risk of Hepatocellular Carcinoma.
Xiyan Xiang, Kirti Shetty, Herbert Yu, Bibhuti Mishra, Linda L Wong, Brandon Mathew, Nabil N Dagher, Aiwu R He

Liver Int· October 2025

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Feasibility of Personalized and Tumor-Informed Circulating Tumor DNA Assay for Early Recurrence Detection in Patients With Hepatocellular Carcinoma.
Maen Abdelrahim, Alejandro Mejia, Abdullah Esmail, Juan Carlos Barrera Gutierrez, Mahmoud Ouf, Catherine Bridges, Vasily N Aushev, Aiwu Ruth He

JCO Precis Oncol· July 2025

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A phase II single-arm study of combination pembrolizumab and olaparib in the treatment of patients with advanced biliary tract cancer.
Narayanan Sadagopan, Hongkun Wang, Chao Yin, Benjamin Adam Weinberg, Marcus Smith Noel, Reetu Mukherji, Aiwu Ruth He

NPJ Precis Oncol· July 2025

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Nivolumab plus ipilimumab versus lenvatinib or sorafenib as first-line treatment for unresectable hepatocellular carcinoma (CheckMate 9DW): an open-label, randomised, phase 3 trial.
Thomas Yau, Peter R Galle, Thomas Decaens, Bruno Sangro, Shukui Qin, Michael Schenker, Aiwu He

Lancet· May 2025

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Combining Radioembolization and Immune Checkpoint Inhibitors for the Treatment of Hepatocellular Carcinoma: The Quest for Synergy.
Christopher D Malone, Suryansh Bajaj, Aiwu He, Kabir Mody, Ryan M Hickey

J Vasc Interv Radiol· March 2025

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Outcomes in the Asian subgroup of the phase III randomised HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma.
George Lau, Ghassan K Abou-Alfa, Ann-Lii Cheng, Wattana Sukeepaisarnjaroen, Tu Van Dao, Satheesh Chiradoni Thungappa, Aiwu Ruth He, Stephen L Chan

J Hepatol· February 2025

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Detecting Early Recurrence With Circulating Tumor DNA in Stage I-III Biliary Tract Cancer After Curative Resection.
James Yu, Aiwu Ruth He, Mahmoud Ouf, Rutika Mehta, Daniel A Anaya, Catherine Bridges, Vasily N Aushev

JCO Precis Oncol· January 2025

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Longitudinal Circulating Tumor Cell Collection, Culture, and Characterization in Pancreatic Adenocarcinomas.
Jerry Xiao, Reetu Mukherji, George Sidarous, Shravanthy Suguru, Marcus Noel, Aiwu He

Cancers (Basel)· January 2025

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Intra-arterial locoregional therapies for intrahepatic cholangiocarcinoma.
Sandhya Patel, Alina Hasanain, Adam Fang, Mohammad Mahdi Khavandi, Trevor Mathias, Emil I Cohen, Saher S Sabri, Aiwu R He

Expert Rev Gastroenterol Hepatol· September 2024

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Durvalumab or placebo plus gemcitabine and cisplatin in participants with advanced biliary tract cancer (TOPAZ-1): updated overall survival from a randomised phase 3 study.
Do-Youn Oh, Aiwu Ruth He, Mohamed Bouattour, Takuji Okusaka, Shukui Qin, Li-Tzong Chen, Ming-Huang Chen, Jen-Shi Chen, David B Zhen, Gary L Buchschacher

Lancet Gastroenterol Hepatol· August 2024

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Patterns of Failure Following Preoperative Chemotherapy and Stereotactic Body Radiation Therapy and Resection for Patients with Borderline Resectable or Locally Advanced Pancreatic Cancer.
Nicole Libbey, Lindsey Gallagher, Jonathan Cantalino, Benjamin A Weinberg, Marcus S Noel, Aiwu R He

J Gastrointest Cancer· June 2024

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Advances in Immunotherapy for Transplant Oncology.
Maen Abdelrahim, Abdullah Esmail, Aiwu Ruth He, Moh'd Khushman, Yaser Rayyan

Cancers (Basel)· June 2024

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Detection of γ-OHPdG in Circulating Tumor Cells of Patients With Hepatocellular Carcinoma as a Potential Prognostic Biomarker of Recurrence.
Monika Aggarwal, Mark Kuo, Zizhao Zhu, Sophie Gould, Kevin Zhang, Samira Beheshtian, Aiwu Ruth He

Gastro Hep Adv· April 2024

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Phase 1 Study of Hypofractionated Proton Beam Radiation Therapy in Adjuvant Pancreatic Cancer (PROTON-PANC).
Benjamin A Weinberg, Hongkun Wang, Marcus S Noel, Aiwu R He, John L Marshall

Int J Radiat Oncol Biol Phys· February 2024

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Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis.
Xiyan Xiang, Krishanu Bhowmick, Kirti Shetty, Kazufumi Ohshiro, Xiaochun Yang, Herbert Yu, Aiwu R He

Genes Cancer· February 2024

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Recent Progress in Systemic Therapy for Advanced Hepatocellular Carcinoma.
Narayanan Sadagopan, Aiwu Ruth He

Int J Mol Sci· January 2024

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Plain language summary of the TOPAZ-1 study: durvalumab and chemotherapy for advanced biliary tract cancer.
Do-Youn Oh, Aiwu Ruth He, Shukui Qin, Li-Tzong Chen, Takuji Okusaka, Jen-Shi Chen, Gordon Cohen

Future Oncol· November 2023

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Surgical resection criteria and neoadjuvant therapies for intrahepatic cholangiocarcinoma.
James O'Bryan, Narayanan Sadagopan, Emily Winslow, Pejman Radkani, Thomas Fishbein, Emil Cohen, Aiwu Ruth He

Clin Adv Hematol Oncol· November 2023

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Hepatocellular Carcinoma: Past and Present Challenges and Progress in Molecular Classification and Precision Oncology.
Philip Coffin, Aiwu He

Int J Mol Sci· August 2023

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Tumor biology and immune infiltration define primary liver cancer subsets linked to overall survival after immunotherapy.
Anuradha Budhu, Erica C Pehrsson, Aiwu He, Lipika Goyal, Robin Kate Kelley, Stephen M Hewitt, Jyoti Shetty, Tsai-Wei Shen

Cell Rep Med· June 2023

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Propagated Circulating Tumor Cells Uncover the Potential Role of NFκB, EMT, and TGFβ Signaling Pathways and in Metastasis.
Jerry Xiao, Utsav Sharma, Abolfazl Arab, Sohit Miglani, Sonakshi Bhalla, Reetu Mukherji, Aiwu Ruth He

Cancers (Basel)· March 2023

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Bridging and downstaging with TACE in early and intermediate stage hepatocellular carcinoma: Predictors of receiving a liver transplant.
Chao Yin, Samantha Armstrong, Richard Shin, Xue Geng, Hongkun Wang, Aiwu Ruth He

Ann Gastroenterol Surg· March 2023

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Clinical outcomes by Child-Pugh Class in patients with advanced hepatocellular carcinoma in a community oncology setting.
Abdalla Aly, Nicole Fulcher, Brian Seal, Trang Pham, Yunfei Wang, Aiwu R He

Hepat Oncol· March 2023

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