Publications by authors named "Ajit Chavan"

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A randomized trial to evaluate the pharmacokinetics, pharmacodynamics, and safety of vadadustat in patients with anemia associated with chronic kidney disease receiving hemodialysis.
Pamela Navarro-Gonzales, Ajit Chavan, Don Wang, Steven K Burke, Kevin Dykstra

BMC Nephrol· August 2025

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Effect of Phosphate Binders and a Dietary Iron Supplement on the Pharmacokinetics of a Single Dose of Vadadustat in Healthy Adults.
Susan K Paulson, Jimena Martinez, Rishikesh Sawant, Steven K Burke, Ajit Chavan

Clin Pharmacol Drug Dev· April 2022

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Effect of Moderate Hepatic Impairment on the Pharmacokinetics of Vadadustat, an Oral Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor.
Ajit Chavan, Leontia Burke, Rishikesh Sawant, Pamela Navarro-Gonzales, Dennis Vargo

Clin Pharmacol Drug Dev· August 2021

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Structure-based discovery of LpxC inhibitors.
Jing Zhang, Audrey Chan, Blaise Lippa, Jason B Cross, Christopher Liu, Ajit Chavan

Bioorg Med Chem Lett· April 2017

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A first-in-Asian phase 1 study to evaluate safety, pharmacokinetics and clinical activity of VS-6063, a focal adhesion kinase (FAK) inhibitor in Japanese patients with advanced solid tumors.
Toshio Shimizu, Kazuya Fukuoka, Masayuki Takeda, Tutomu Iwasa, Takeshi Yoshida, Ajit Chavan

Cancer Chemother Pharmacol· May 2016

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Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
Jing Zhang, Qingyi Yang, Jason B Cross, Jan Antoinette C Romero, Katherine M Poutsiaka, Ajit Chavan

J Med Chem· November 2015

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Clinical drug-drug interaction assessment of ivacaftor as a potential inhibitor of cytochrome P450 and P-glycoprotein.
Sarah M Robertson, Xia Luo, Neeraj Dubey, Chonghua Li, Ajit B Chavan

J Clin Pharmacol· January 2015

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