Publications by authors named "Akihiro Taguchi"

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Structure-Activity Relationship Study of Affinity Peptides for the Fc Site of Human Immunoglobulin G.
Kyohei Muguruma, Akane Fukuda, Hayate Shida, Rento Osawa, Soichiro Harigaya, Akihiro Taguchi

Chem Pharm Bull (Tokyo)· December 2025

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Exploring the Substrate Flexibility of GrsB Thioesterase Leads to the Structural Reassignment of a Gramicidin S Variant.
Sho Konno, Tomoe Mizuguchi, Atsuko Suzuki, Miyu Tanaka, Fumihiro Ishikawa, Akihiro Taguchi

Chembiochem· November 2025

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Backbone resonance assignments of the C-terminal thioesterase domain of tyrocidine synthetase C.
Mitsuhiro Takeda, Rino Saito, Sho Konno, Takayuki Nagae, Hiroshi Aoyama, Akihiro Taguchi

Biomol NMR Assign· June 2025

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Development of Water-Soluble 3-Nitro-2-Pyridinesulfenate for Disulfide Bond Formation of Peptide Under Aqueous Conditions.
Akihiro Taguchi, Megumi Sakata, Ryusei Yamamoto, Hayate Shida, Saeka Kuraishi

Chemistry· June 2025

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Structure Derivatization of IgG-Binding Peptides and Analysis of Their Secondary Structure by Circular Dichroism Spectroscopy.
Kyohei Muguruma, Akane Fukuda, Hayate Shida, Akihiro Taguchi, Kentaro Takayama

Chem Pharm Bull (Tokyo)· September 2024

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Discovery of a Pentapeptide Antagonist to Human Neuromedin U Receptor 1.
Kentaro Takayama, Kenji Mori, Yu Sasaki, Akihiro Taguchi, Atsuhiko Taniguchi

ACS Med Chem Lett· June 2024

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Detection of Active SARS-CoV-2 3CL Protease in Infected Cells Using Activity-Based Probes with a 2,6-Dichlorobenzoyloxymethyl Ketone Reactive Warhead.
Yuki Yamauchi, Sho Konno, Noriko Omura, Narumi Yoshioka, Alexandra Hingst, Akihiro Taguchi

ACS Chem Biol· May 2024

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Peptide mixed phosphonates for covalent complex formation with thioesterases in nonribosomal peptide synthetases.
Sho Konno, Miyu Tanaka, Tomoe Mizuguchi, Haruka Toyokai, Akihiro Taguchi

J Pept Sci· January 2024

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[Development of Synthetic Methodology for Mid-size Peptide Based on Disulfide Bond Formation].
Akihiro Taguchi

Yakugaku Zasshi· December 2023

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Development of Conformationally Restricted Negamycin Derivatives for Potent Readthrough Activity.
Noriko Omura, Akihiro Taguchi, Tomoki Kuwahara, Keisuke Hamada, Mizuki Watanabe

ACS Med Chem Lett· December 2023

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Development of a novel fluorogenic assay method for screening inhibitors of bovine leukemia virus protease and identification of mitorubrinic acid as an anti-BLV compound.
Hironobu Murakami, Yuuta Fujikawa, Masaya Mori, Nozomi Mosu, Akihiro Taguchi

Biosci Biotechnol Biochem· August 2023

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X-Ray Conformation and Structure-Activity Relationships of MA026, a Reversible Tight Junction Opener.
Minagi Mukaiyama, Chihiro Uchiyama, Akane Fukuda, Yoshiki Nakazawa, Yuka Kuramochi, Akihiro Taguchi

J Med Chem· July 2023

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Establishment of One-Pot Disulfide-Driven Cyclic Peptide Synthesis with a 3-Nitro-2-pyridinesulfenate.
Hayate Shida, Akihiro Taguchi, Sho Konno, Kentaro Takayama, Atsuhiko Taniguchi

Chem Pharm Bull (Tokyo)· June 2023

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Inactivation of myostatin by photooxygenation using functionalized d-peptides.
Hideyuki Okamoto, Shuko Amber Murano, Kaoru Ikekawa, Masahiro Katsuyama, Sho Konno, Akihiro Taguchi

RSC Med Chem· February 2023

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Influence of novel readthrough agents on myelin protein zero translation in the peripheral nervous system.
Yoshinori Otani, Akihiro Taguchi, Keisuke Hamada, Yoshio Hayashi, Yoshihide Yamaguchi

Neuropharmacology· June 2022

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Development of Myostatin Inhibitory d-Peptides to Enhance the Potency, Increasing Skeletal Muscle Mass in Mice.
Kentaro Takayama, Keisuke Hitachi, Hideyuki Okamoto, Mariko Saitoh, Miki Odagiri, Akihiro Taguchi

ACS Med Chem Lett· March 2022

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3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents.
Sho Konno, Kiyotaka Kobayashi, Miki Senda, Yuta Funai, Yuta Seki, Akihiro Taguchi

J Med Chem· February 2022

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Strategic structure-activity relationship study on a follistatin-derived myostatin inhibitory peptide.
Mariko Saitoh, Kentaro Takayama, Yoshimi Roppongi, Takahiro Shimada, Akihiro Taguchi

Bioorg Med Chem Lett· August 2021

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Development of a High-Affinity Antibody-Binding Peptide for Site-Specific Modification.
Kyohei Muguruma, Rento Osawa, Akane Fukuda, Naoto Ishikawa, Konomi Fujita, Akihiro Taguchi

ChemMedChem· June 2021

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Proposal for the binding mode of the 23-mer inhibitory peptide to myostatin.
Tomo Asari, Hiroaki Ikeyama, Akihiro Taguchi, Atsuhiko Taniguchi, Yoshio Hayashi

Bioorg Med Chem· June 2021

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Structural Revision of Natural Cyclic Depsipeptide MA026 Established by Total Synthesis and Biosynthetic Gene Cluster Analysis.
Chihiro Uchiyama, Akane Fukuda, Minagi Mukaiyama, Yoshiki Nakazawa, Yuka Kuramochi, Akihiro Taguchi

Angew Chem Int Ed Engl· April 2021

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Enzymatic Stability of Myostatin Inhibitory 16-mer Peptides.
Kentaro Takayama, Miki Odagiri, Akihiro Taguchi, Atsuhiko Taniguchi, Yoshio Hayashi

Chem Pharm Bull (Tokyo)· January 2021

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Development of functionalized peptides for efficient inhibition of myostatin by selective photooxygenation.
Hideyuki Okamoto, Atsuhiko Taniguchi, Shoya Usami, Masahiro Katsuyama, Sho Konno, Akihiro Taguchi

Org Biomol Chem· January 2021

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Design and synthesis of peptidic partial agonists of human neuromedin U receptor 1 with enhanced serum stability.
Kentaro Takayama, Kenji Mori, Tomo Asari, Yuko Sohma, Erina Nomura, Akihiro Taguchi

Bioorg Med Chem Lett· September 2020

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Use of solid-supported 4-fluorophenyl 3-nitro-2-pyridinesulfenate in the construction of disulfide-linked hybrid molecules.
Yan Cui, Akihiro Taguchi, Kiyotaka Kobayashi, Hayate Shida, Kentaro Takayama

Org Biomol Chem· September 2020

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