Publications by authors named "Akiko Koeda"

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Multisite studies for optimization of a highly efficient culture assay used for detection of residual undifferentiated human pluripotent stem cells intermingled in cell therapy products.
Takeshi Watanabe, Satoshi Yasuda, Shinji Kusakawa, Takuya Kuroda, Hatsue Furukawa, Akiko Koeda

Regen Ther· June 2024

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Collaborative Study of Thresholds for Mutagens: Adaptive Responses in the Micronucleus Test and Gene Induction by Mutagenic Treatments.
Shizuyo Sutou, Akiko Koeda, Kana Komatsu, Toshiyuki Shiragiku, Hiroshi Seki

Dose Response· May 2024

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Collaborative Study of Thresholds for Mutagens: Hormetic Responses in Cell Proliferation Tests Using Human and Murine Lymphoid Cells.
Shizuyo Sutou, Akiko Koeda, Kana Komatsu, Toshiyuki Shiragiku, Hiroshi Seki

Dose Response· June 2021

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Comparison of the inducibility of CYP mRNA exposed to typical inducers in fresh and cryopreserved cynomolgus monkey hepatocytes.
Akiko Koeda, Takahiro Iwao, Anna Nakanishi, Shota Mizuno, Misaki Yamashita

Drug Metab Pharmacokinet· June 2020

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Comparison of mRNA expression profiles of drug-metabolizing enzymes and transporters in fresh and cryopreserved cynomolgus monkey hepatocytes.
Akiko Koeda, Takahiro Iwao, Anna Nakanishi, Shota Mizuno, Misaki Yamashita

Drug Metab Pharmacokinet· August 2019

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Collaborative study of thresholds for mutagens: proposal of a typical protocol for detection of hormetic responses in cytotoxicity tests.
Shizuyo Sutou, Akiko Koeda, Kana Komatsu, Toshiyuki Shiragiku, Hiroshi Seki

Genes Environ· October 2018

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Efficient Generation of Cynomolgus Monkey Induced Pluripotent Stem Cell-Derived Intestinal Organoids with Pharmacokinetic Functions.
Daichi Onozato, Misaki Yamashita, Ryosuke Fukuyama, Takumi Akagawa, Yuriko Kida, Akiko Koeda

Stem Cells Dev· August 2018

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Evaluation of human hepatocytes cultured by three-dimensional spheroid systems for drug metabolism.
Takako Ohkura, Kunihiro Ohta, Takuya Nagao, Kumiko Kusumoto, Akiko Koeda

Drug Metab Pharmacokinet· October 2015

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Evaluation of a repeated-dose liver micronucleus assay with 2,6-dinitrotoluene using young adult rats.
Tadashi Imamura, Akiko Koeda, Kiyoshi Morimoto, Hirofumi Hatakeyama, Hiroshi Suzuki

Mutat Res Genet Toxicol Environ Mutagen· March 2015

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Characterization of marmoset CYP2B6: cDNA cloning, protein expression and enzymatic functions.
Kei Mayumi, Nobumitsu Hanioka, Kazufumi Masuda, Akiko Koeda, Shinsaku Naito

Biochem Pharmacol· April 2013

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Discrimination of genotoxic and non-genotoxic hepatocarcinogens by statistical analysis based on gene expression profiling in the mouse liver as determined by quantitative real-time PCR.
Takashi Watanabe, Takayoshi Suzuki, Masakatsu Natsume, Madoka Nakajima, Kazunori Narumi, Akiko Koeda

Mutat Res· September 2012

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Genotoxicity studies of 2,6-dinitrotoluene (2,6-DNT).
Hiroshi Suzuki, Tadashi Imamura, Akiko Koeda, Kiyoshi Morimoto, Yoshio Wakasa

J Toxicol Sci· August 2011

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Regio- and stereoselective oxidation of propranolol enantiomers by human CYP2D6, cynomolgus monkey CYP2D17 and marmoset CYP2D19.
Shizuo Narimatsu, Toshiyuki Nakata, Takeshi Shimizudani, Kenjiro Nagaoka, Hironori Nakura, Akiko Koeda

Chem Biol Interact· February 2011

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Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes.
Nobumitsu Hanioka, Natsuko Tanabe, Hideto Jinno, Toshiko Tanaka-Kagawa, Kenjiro Nagaoka, Akiko Koeda

Life Sci· August 2010

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Tissue-specific mRNA expression profiles of drug-metabolizing enzymes and transporters in the cynomolgus monkey.
Masuhiro Nishimura, Akiko Koeda, Hiroshi Morikawa, Tetsuo Satoh, Shizuo Narimatsu

Drug Metab Pharmacokinet· November 2009

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Stereoselective glucuronidation of propranolol in human and cynomolgus monkey liver microsomes: role of human hepatic UDP-glucuronosyltransferase isoforms, UGT1A9, UGT2B4 and UGT2B7.
Nobumitsu Hanioka, Keiko Hayashi, Takeshi Shimizudani, Kenjiro Nagaoka, Akiko Koeda

Pharmacology· February 2009

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Comparison of inducibility of multidrug resistance (MDR)1, multidrug resistance-associated protein (MRP)1, and MRP2 mRNAs by prototypical microsomal enzyme inducers in primary cultures of human and cynomolgus monkey hepatocytes.
Masuhiro Nishimura, Akiko Koeda, Hiroshi Morikawa, Tetsuo Satoh, Shizuo Narimatsu

Biol Pharm Bull· November 2008

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Comparison of inducibility of sulfotransferase and UDP-glucuronosyltransferase mRNAs by prototypical microsomal enzyme inducers in primary cultures of human and cynomolgus monkey hepatocytes.
Masuhiro Nishimura, Akiko Koeda, Takefumi Shimizu, Mitsuo Nakayama, Tetsuo Satoh

Drug Metab Pharmacokinet· April 2008

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Comparison of inducibility of CYP1A and CYP3A mRNAs by prototypical inducers in primary cultures of human, cynomolgus monkey, and rat hepatocytes.
Masuhiro Nishimura, Akiko Koeda, Yasuyuki Suganuma, Emako Suzuki, Takefumi Shimizu

Drug Metab Pharmacokinet· June 2007

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Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A6 enzymes.
Nobumitsu Hanioka, Yuri Takeda, Hideto Jinno, Toshiko Tanaka-Kagawa, Shinsaku Naito, Akiko Koeda

Chem Biol Interact· December 2006

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Effects of prototypical drug-metabolizing enzyme inducers on mRNA expression of housekeeping genes in primary cultures of human and rat hepatocytes.
Masuhiro Nishimura, Akiko Koeda, Emako Suzuki, Takefumi Shimizu, Yuichi Kawano

Biochem Biophys Res Commun· August 2006

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Regulation of mRNA expression of MDR1, MRP1, MRP2 and MRP3 by prototypical microsomal enzyme inducers in primary cultures of human and rat hepatocytes.
Masuhiro Nishimura, Akiko Koeda, Emako Suzuki, Yuichi Kawano, Mitsuo Nakayama

Drug Metab Pharmacokinet· August 2006

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