Publications by authors named "Akio Fujimura"

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Night-Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial.
Kentaro Ushijima, Yukihiro Sanada, Shinya Otomo, Keiko Ogaki, Taiichi Wakiya, Akio Fujimura

Clin Pharmacol Ther· August 2025

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Aging Reduces ATP-Binding Cassette Transporter Expression in Brain Microvessels of Mice.
Yukiyo Wada, Masaki Inoko, Kanako Ishihara, Karin Fukumoto, Yuya Tsurudome, Akio Fujimura

Pharmaceuticals (Basel)· January 2025

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Understanding the role of chronopharmacology for drug optimization: what do we know?
Akio Fujimura, Kentaro Ushijima

Expert Rev Clin Pharmacol· November 2023

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Potential mechanism of hepatic lipid accumulation during a long-term rest phase restricted feeding in mice.
Yuya Tsurudome, Takahiro Akamine, Michiko Horiguchi, Yukiyo Wada, Akio Fujimura

Chronobiol Int· August 2022

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Chronic Treatment with Metformin Has No Disrupting Effect on the Hepatic Circadian Clock in Mice.
Nazmul Hasan, Koki Sugimoto, Koki Yamada, Jun-Ichi Morishige, Kentaro Ushijima, Akio Fujimura

Medicina (Kaunas)· February 2022

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Brown adipocyte-specific knockout of Bmal1 causes mild but significant thermogenesis impairment in mice.
Nazmul Hasan, Naoto Nagata, Jun-Ichi Morishige, Md Tarikul Islam, Zheng Jing, Akio Fujimura

Mol Metab· July 2021

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Edoxaban Dosing Time Affects Blood Coagulation Inhibition in Rats.
Naoto Nagata, Muneo Kawasumi, Akio Fujimura, Hitoshi Ando

TH Open· April 2021

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Presence of the aldehyde dehydrogenase 2 variant ALDH2*2 considerably increases EC of nitroglycerin.
Kentaro Ushijima, Chika Ogami, Yasuhiro Tsuji, Tatsuya Nagano, Akio Fujimura

Eur J Clin Pharmacol· March 2021

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Guidelines for the design and conduct of human clinical trials on ingestion-time differences - chronopharmacology and chronotherapy - of hypertension medications.
Ramón C Hermida, Michael H Smolensky, Horia Balan, Richard J Castriotta, Juan J Crespo, Akio Fujimura

Chronobiol Int· January 2021

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Expression of clock gene in omental and mesenteric adipose tissue in patients with type 2 diabetes.
Kentaro Ushijima, Chisato Suzuki, Hiroko Kitamura, Ken Shimada, Hirotoshi Kawata, Akio Fujimura

BMJ Open Diabetes Res Care· August 2020

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COVID-19 infection at nighttime.
Akio Fujimura, Kentaro Ushijima, Michael H Smolensky

Chronobiol Int· May 2020

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Influence of renal ischaemia-reperfusion injury on renal neutrophil gelatinase-associated lipocalin receptor (24p3R) in rats.
Yusuke Arakawa, Kentaro Ushijima, Hiroyoshi Tsuchiya, Jun-Ichi Morishige, Akiko Mii, Akio Fujimura

Clin Exp Pharmacol Physiol· December 2019

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Influence of the aldehyde dehydrogenase 2 polymorphism on the vasodilatory effect of nitroglycerin in infants with congenital heart disease and pulmonary arterial hypertension.
Tatsuya Nagano, Kentaro Ushijima, Naoyuki Taga, Mamoru Takeuchi, Masa-Aki Kawada, Akio Fujimura

Eur J Clin Pharmacol· October 2019

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Induction of by a histone deacetylase inhibitor is involved in amelioration of insulin sensitivity via adipocyte differentiation in ob/ob mice.
Chisato Suzuki, Kentaro Ushijima, Hitoshi Ando, Hiroko Kitamura, Michiko Horiguchi, Akio Fujimura

Chronobiol Int· July 2019

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Associations among regorafenib concentrations, severe adverse reactions, and ABCG2 and OATP1B1 polymorphisms.
Akimitsu Maeda, Kei Irie, Hitoshi Ando, Ayako Hasegawa, Hiroya Taniguchi, Akio Fujimura

Cancer Chemother Pharmacol· January 2019

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Increased tacrolimus blood concentration by Beni-Madonna - a new hybrid citrus cultivar categorized as 'Tangor', in a liver transplant patient: likely furanocoumarin-mediated inhibition of CYP3A4 or P-glycoprotein.
Kentaro Ushijima, Koichi Mizuta, Shinya Otomo, Keiko Ogaki, Yukihiro Sanada, Akio Fujimura

Br J Clin Pharmacol· December 2018

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Chronotherapy of maxacalcitol on skin inflammation induced by topical 12-O-tetradecanoylphorbol-13-acetate in mice.
Daisuke Yoshioka, Hitoshi Ando, Kentaro Ushijima, Masafumi Kumazaki, Akio Fujimura

Chronobiol Int· September 2018

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Pulmonary administration of curcumin inhibits B16F10 melanoma lung metastasis and invasion in mice.
Ken Shimada, Kentaro Ushijima, Chisato Suzuki, Michiko Horiguchi, Hitoshi Ando, Akio Fujimura

Cancer Chemother Pharmacol· August 2018

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Complex formation between the vasopressin 1b receptor, β-arrestin-2, and the μ-opioid receptor underlies morphine tolerance.
Taka-Aki Koshimizu, Kenji Honda, Sachi Nagaoka-Uozumi, Atsuhiko Ichimura, Ikuo Kimura, Akio Fujimura

Nat Neurosci· June 2018

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Influence of a dosing-time on toxicities induced by docetaxel, cisplatin and 5-fluorouracil in patients with oral squamous cell carcinoma; a cross-over pilot study.
Yoshiyuki Tsuchiya, Kentaro Ushijima, Tadahide Noguchi, Naruo Okada, Jun-Ichi Hayasaka, Akio Fujimura

Chronobiol Int· February 2018

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Differences in Urinary Renal Failure Biomarkers in Cancer Patients Initially Treated with Cisplatin.
Akimitsu Maeda, Hitoshi Ando, Takashi Ura, Kei Muro, Masahiro Aoki, Akio Fujimura

Anticancer Res· September 2017

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Prevention against renal damage in rats with subtotal nephrectomy by sacubitril/valsartan (LCZ696), a dual-acting angiotensin receptor-neprilysin inhibitor.
Kentaro Ushijima, Hitoshi Ando, Yusuke Arakawa, Kenichi Aizawa, Chisato Suzuki, Akio Fujimura

Pharmacol Res Perspect· August 2017

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Dosing-time-dependent effect of rivaroxaban on coagulation activity in rats.
Yuki Fujiwara, Hitoshi Ando, Kentaro Ushijima, Michiko Horiguchi, Chikamasa Yamashita, Akio Fujimura

J Pharmacol Sci· August 2017

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Association between ABCG2 and SLCO1B1 polymorphisms and adverse drug reactions to regorafenib: a preliminary study
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Akimitsu Maeda, Hitoshi Ando, Takashi Ura, Azusa Komori, Ayako Hasegawa, Akio Fujimura

Int J Clin Pharmacol Ther· May 2017

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Effect of a dosing-time on quetiapine-induced acute hyperglycemia in mice.
Snehal Kapse, Hitoshi Ando, Yuki Fujiwara, Chisato Suzuki, Kentaro Ushijima, Akio Fujimura

J Pharmacol Sci· March 2017

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