Publications by authors named "Akiyoshi Uezumi"

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Overuse-Induced Muscle Disorder: Establishing a Rat Model to Unravel the Role of Fibro-Adipogenic Progenitor Cells in Intramuscular Fibrosis.
Hiroyori Fusagawa, Tatsuya Sato, Azuma Naito, Nao Tokuda, Nao Yamauchi, Akiyoshi Uezumi, Madoka Uezumi

J Orthop Res· December 2025

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Critical role of mitochondrial aconitase in skeletal muscle maturation.
Tomoya Fukawa, Miho Takata, Kota Kishida, Kosuke Sugiura, Minori Suzuki, Madoka Ikemoto-Uezumi, Akiyoshi Uezumi

Sci Rep· December 2025

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Calcitonin receptor downregulation and exercise-conditioned blood enable systemic muscle stem cell proliferation.
Lidan Zhang, Takayuki Kaji, Ayasa Nakamura, Nagomu Maesawa, Kanako Iwamori, Akiyoshi Uezumi

Nat Commun· November 2025

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Epidermal growth factor receptor contributes to indirect regulation of skeletal muscle mass by androgen.
Tomoya Onishi, Hiroshi Sakai, Hideaki Uno, Iori Sakakibara, Akiyoshi Uezumi

Endocr J· March 2025

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PDZRN3 regulates adipogenesis of mesenchymal progenitors in muscle.
Hiroki Iida, Minako Kawai-Takaishi, Yoshihiro Miyagawa, Yasuhiko Takegami, Akiyoshi Uezumi

Regen Ther· March 2025

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Tissue-specific functions of MSCs are linked to homeostatic muscle maintenance and alter with aging.
Tamaki Kurosawa, Madoka Ikemoto-Uezumi, Yuki Yoshimoto, Keitaro Minato, Noriyuki Kaji, Akiyoshi Uezumi

Aging Cell· November 2024

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Ror2 signaling regulated by differential Wnt proteins determines pathological fate of muscle mesenchymal progenitors.
Koki Kamizaki, Mitsuko Katsukawa, Ayano Yamamoto, So-Ichiro Fukada, Akiyoshi Uezumi

Cell Death Dis· October 2024

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The androgen receptor in mesenchymal progenitors regulates skeletal muscle mass via expression in male mice.
Hiroshi Sakai, Hideaki Uno, Harumi Yamakawa, Kaori Tanaka, Aoi Ikedo, Akiyoshi Uezumi

Proc Natl Acad Sci U S A· September 2024

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Lack of vitamin D signalling in mesenchymal progenitors causes fatty infiltration in muscle.
Tohru Hosoyama, Minako Kawai-Takaishi, Hiroki Iida, Yoko Yamamoto, Yuko Nakamichi, Akiyoshi Uezumi

J Cachexia Sarcopenia Muscle· June 2024

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Regulation of muscle hypertrophy through granulin: Relayed communication among mesenchymal progenitors, macrophages, and satellite cells.
Lidan Zhang, Hayato Saito, Tatsuyoshi Higashimoto, Takayuki Kaji, Ayasa Nakamura, Akiyoshi Uezumi

Cell Rep· April 2024

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Transcriptome analysis of mesenchymal stromal cells of the large and small intestinal smooth muscle layers reveals a unique gastrontestinal stromal signature.
Takashi Chaen, Tamaki Kurosawa, Kazuhisa Kishi, Noriyuki Kaji, Madoka Ikemoto-Uezumi, Akiyoshi Uezumi

Biochem Biophys Rep· July 2023

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Roles and Heterogeneity of Mesenchymal Progenitors in Muscle Homeostasis, Hypertrophy, and Disease.
So-Ichiro Fukada, Akiyoshi Uezumi

Stem Cells· June 2023

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Adipose tissue boosts muscle regeneration by supplying mesenchymal stromal cells.
Akiyoshi Uezumi

Nat Rev Endocrinol· June 2023

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Analyses of Mesenchymal Progenitors in Skeletal Muscle by Fluorescence-Activated Cell Sorting and Tissue Clearing.
Madoka Ikemoto-Uezumi, Tamaki Kurosawa, Keitaro Minato, Akiyoshi Uezumi

Methods Mol Biol· April 2023

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Depletion of CD206 M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration.
Allah Nawaz, Muhammad Bilal, Shiho Fujisaka, Tomonobu Kado, Muhammad Rahil Aslam, Akiyoshi Uezumi

Nat Commun· November 2022

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Whole-mount immunofluorescence staining of mesenchymal progenitors in murine plantaris muscle.
Tamaki Kurosawa, Madoka Ikemoto-Uezumi, Akihiro Kaneshige, So-Ichiro Fukada, Akiyoshi Uezumi

STAR Protoc· September 2022

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Detection of muscle stem cell-derived myonuclei in murine overloaded muscles.
Akihiro Kaneshige, Takayuki Kaji, Hayato Saito, Tatsuyoshi Higashimoto, Ayasa Nakamura, Madoka Ikemoto-Uezumi, Akiyoshi Uezumi

STAR Protoc· June 2022

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Tenogenic Induction From Induced Pluripotent Stem Cells Unveils the Trajectory Towards Tenocyte Differentiation.
Yuki Yoshimoto, Akiyoshi Uezumi, Madoka Ikemoto-Uezumi, Kaori Tanaka, Xinyi Yu

Front Cell Dev Biol· March 2022

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Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load.
Akihiro Kaneshige, Takayuki Kaji, Lidan Zhang, Hayato Saito, Ayasa Nakamura, Madoka Ikemoto-Uezumi, Akiyoshi Uezumi

Cell Stem Cell· February 2022

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Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle.
Naoki Takada, Masaki Takasugi, Yoshiki Nonaka, Tomonori Kamiya, Kazuaki Takemura, Akiyoshi Uezumi

Development· February 2022

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Increased MFG-E8 at neuromuscular junctions is an exacerbating factor for sarcopenia-associated denervation.
Madoka Ikemoto-Uezumi, Heying Zhou, Tamaki Kurosawa, Yuki Yoshimoto, Masashi Toyoda, Akiyoshi Uezumi

Aging Cell· January 2022

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Measurement of Lateral Transmission of Force in the Extensor Digitorum Longus Muscle of Young and Old Mice.
Keitaro Minato, Yuki Yoshimoto, Tamaki Kurosawa, Kei Watanabe, Hiroyuki Kawashima, Madoka Ikemoto-Uezumi, Akiyoshi Uezumi

Int J Mol Sci· November 2021

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Transgenic Expression of in Mesenchymal Progenitors Mitigates Age-Related Muscle Mass Loss and Neuromuscular Junction Degeneration.
Tamaki Kurosawa, Keitaro Minato, Madoka Ikemoto-Uezumi, Jun Hino, Kunihiro Tsuchida, Akiyoshi Uezumi

Int J Mol Sci· September 2021

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Collagen-VI supplementation by cell transplantation improves muscle regeneration in Ullrich congenital muscular dystrophy model mice.
Nana Takenaka-Ninagawa, Jinsol Kim, Mingming Zhao, Masae Sato, Tatsuya Jonouchi, Akiyoshi Uezumi

Stem Cell Res Ther· August 2021

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Retinoic Acid Receptor Agonists Suppress Muscle Fatty Infiltration in Mice.
Hideyuki Shirasawa, Noboru Matsumura, Masaki Yoda, Kazumasa Okubo, Masayuki Shimoda, Akiyoshi Uezumi

Am J Sports Med· February 2021

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