Publications by authors named "Akram Alian"

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Identification of founder and novel mutations that cause congenital insensitivity to pain (CIP) in palestinian patients.
Boushra Khaled, Mahmoud Alzahayqa, Ahmad Jaffal, Husam Sallam, Rua'a Thawabta, Akram Alian

BMC Med Genomics· May 2023

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Interactions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release.
Lara Rheinemann, Tuscan Thompson, Gaelle Mercenne, Elliott L Paine, Francis C Peterson, Akram Alian

J Biol Chem· August 2021

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The structure of FIV reverse transcriptase and its implications for non-nucleoside inhibitor resistance.
Meytal Galilee, Akram Alian

PLoS Pathog· January 2018

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The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical.
Meytal Galilee, Elena Britan-Rosich, Sarah L Griner, Serdar Uysal, Viola Baumgärtel, Akram Alian

Structure· November 2016

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Structure of FIV capsid C-terminal domain demonstrates lentiviral evasion of genetic fragility by coevolved substitutions.
Aya Khwaja, Meytal Galilee, Ailie Marx, Akram Alian

Sci Rep· April 2016

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Zinc enhancement of cytidine deaminase activity highlights a potential allosteric role of loop-3 in regulating APOBEC3 enzymes.
Ailie Marx, Meytal Galilee, Akram Alian

Sci Rep· December 2015

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Rerouting Resistance: Escaping Restriction Using Alternative Cellular Pathways.
Ailie Marx, Akram Alian

Trends Microbiol· October 2015

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T538 phosphorylation, Pin-ing p63-Itch stability.
Akram Alian, Rami I Aqeilan

Cell Cycle· September 2015

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The Road Less Traveled: HIV's Use of Alternative Routes through Cellular Pathways.
Ailie Marx, Akram Alian

J Virol· May 2015

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A novel open-barrel structure of octameric translin reveals a potential RNA entryway.
Elad Eliahoo, Ailie Marx, Haim Manor, Akram Alian

J Mol Biol· February 2015

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The first crystal structure of a dTTP-bound deoxycytidylate deaminase validates and details the allosteric-inhibitor binding site.
Ailie Marx, Akram Alian

J Biol Chem· January 2015

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Identification of Phe187 as a crucial dimerization determinant facilitates crystallization of a monomeric retroviral integrase core domain.
Meytal Galilee, Akram Alian

Structure· October 2014

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The mechanism of pseudouridine synthases from a covalent complex with RNA, and alternate specificity for U2605 versus U2604 between close homologs.
Nadine Czudnochowski, Gary W Ashley, Daniel V Santi, Akram Alian, Janet Finer-Moore

Nucleic Acids Res· February 2014

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Fabs enable single particle cryoEM studies of small proteins.
Shenping Wu, Agustin Avila-Sakar, JungMin Kim, David S Booth, Charles H Greenberg, Akram Alian

Structure· April 2012

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WW domain-containing proteins: retrospectives and the future.
Zaidoun Salah, Akram Alian, Rami I Aqeilan

Front Biosci (Landmark Ed)· January 2012

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Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome.
Akram Alian, Andrew DeGiovanni, Sarah L Griner, Janet S Finer-Moore, Robert M Stroud

J Mol Biol· May 2009

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Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugs.
Akram Alian, Sarah L Griner, Vicki Chiang, Manuel Tsiang, Gregg Jones

Proc Natl Acad Sci U S A· May 2009

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Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases.
Akram Alian, Tom T Lee, Sarah L Griner, Robert M Stroud, Janet Finer-Moore

Proc Natl Acad Sci U S A· May 2008

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Inhibition of the Mycobacterium tuberculosis enoyl acyl carrier protein reductase InhA by arylamides.
Xin He, Akram Alian, Paul R Ortiz de Montellano

Bioorg Med Chem· November 2007

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Cytochrome P450 active site plasticity: attenuation of imidazole binding in cytochrome P450(cam) by an L244A mutation.
Andreas Verras, Akram Alian, Paul R Ortiz de Montellano

Protein Eng Des Sel· November 2006

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Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis.
Xin He, Akram Alian, Robert Stroud, Paul R Ortiz de Montellano

J Med Chem· October 2006

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Human peripheral blood eosinophils induce angiogenesis.
Ilaria Puxeddu, Akram Alian, Adrian Martin Piliponsky, Domenico Ribatti, Amos Panet

Int J Biochem Cell Biol· March 2005

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Replication of HIV-1 deleted Nef mutants in chronically immune activated human T cells.
Orit Shapira-Nahor, Shlomo Maayan, Keith W C Peden, Ruth Rabinowitz, Michael Schlesinger, Akram Alian

Virology· November 2002

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Viral mediated gene transfer to sprouting blood vessels during angiogenesis.
Akram Alian, Amiram Eldor, Haya Falk, Amos Panet

J Virol Methods· August 2002

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