Publications by authors named "Aktan Alpsoy"

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Structural basis of DNA-dependent coactivator recruitment by the tuft cell master regulator POU2F3.
Aktan Alpsoy, Jonathan J Ipsaro, Damianos Skopelitis, Sujay Pal, Frank S Chung

Cell Rep· November 2025

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Addressing the specific roles of histone modifications in transcriptional repression.
Lin Hedehus, Aina M Mas, Aktan Alpsoy, Robin L Armstrong, Richard Koche

Nat Commun· November 2025

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MARK2/MARK3 Kinases Are Catalytic Codependencies of YAP/TAZ in Human Cancer.
Olaf Klingbeil, Damianos Skopelitis, Claudia Tonelli, Toyoki Yoshimoto, Aktan Alpsoy

Cancer Discov· December 2024

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Loss of Bicra/Gltscr1 leads to a defect in fetal liver macrophages responsible for erythrocyte maturation in mice.
Surbhi Sood, Aktan Alpsoy, Guanming Jiao, Alisha Dhiman, Charles Samuel King

bioRxiv· October 2024

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Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma.
Diogo Maia-Silva, Patrick J Cunniff, Allison C Schier, Damianos Skopelitis, Marygrace C Trousdell, Aktan Alpsoy

Nat Genet· July 2024

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IκBζ is a dual-use coactivator of NF-κB and POU transcription factors.
Aktan Alpsoy, Xiaoli S Wu, Sujay Pal, Olaf Klingbeil, Pramod Kumar

Mol Cell· March 2024

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Identification of SWI/SNF Subcomplex GBAF Presence, Intra-Complex Interactions, and Transcriptional Dynamics during Early Porcine Development.
Sarah Innis, Aktan Alpsoy, Jennifer Crodian, Yu-Chun Tseng, Emily Dykhuizen

Animals (Basel)· February 2024

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Marker-based CRISPR screening reveals a MED12-p63 interaction that activates basal identity in pancreatic ductal adenocarcinoma.
Diogo Maia-Silva, Allison C Schier, Damianos Skopelitis, Vahag Kechejian, Aktan Alpsoy

bioRxiv· October 2023

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Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma.
Saul Carcamo, Christie B Nguyen, Elena Grossi, Dan Filipescu, Aktan Alpsoy

Cell Rep· April 2022

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Polycomb Paralog Chromodomain Inhibitors Active against Both CBX6 and CBX8*.
Natalia Milosevich, Chelsea R Wilson, Tyler M Brown, Aktan Alpsoy, Sijie Wang

ChemMedChem· October 2021

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A Potent, Selective CBX2 Chromodomain Ligand and Its Cellular Activity During Prostate Cancer Neuroendocrine Differentiation.
Sijie Wang, Aktan Alpsoy, Surbhi Sood, Sandra Carolina Ordonez-Rubiano, Alisha Dhiman

Chembiochem· July 2021

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At the Crossroad of Gene Regulation and Genome Organization: Potential Roles for ATP-Dependent Chromatin Remodelers in the Regulation of CTCF-Mediated 3D Architecture.
Aktan Alpsoy, Surbhi Sood, Emily C Dykhuizen

Biology (Basel)· March 2021

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BRD9 Is a Critical Regulator of Androgen Receptor Signaling and Prostate Cancer Progression.
Aktan Alpsoy, Sagar M Utturkar, Benjamin C Carter, Alisha Dhiman, Sandra E Torregrosa-Allen

Cancer Res· February 2021

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Poly (I:C)- and doxorubicin-loaded magnetic dendrimeric nanoparticles affect the apoptosis-related gene expressions in MCF-7 cells.
Rouhollah Khodadust, Aktan Alpsoy, Gözde Ünsoy, Ufuk GÜndÜz

Turk J Biol· August 2020

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Selection of DNA-Encoded Libraries to Protein Targets within and on Living Cells.
Bo Cai, Dongwook Kim, Saeed Akhand, Yixing Sun, Robert J Cassell, Aktan Alpsoy

J Am Chem Soc· October 2019

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A chemoproteomic portrait of the oncometabolite fumarate.
Rhushikesh A Kulkarni, Daniel W Bak, Darmood Wei, Sarah E Bergholtz, Chloe A Briney, Aktan Alpsoy

Nat Chem Biol· April 2019

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Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association.
Katelyn E Connelly, Tyler M Weaver, Aktan Alpsoy, Brian X Gu, Catherine A Musselman

Nucleic Acids Res· March 2019

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The Dbf4 ortholog Chiffon forms a complex with Gcn5 that is necessary for histone acetylation and viability.
Eliana F Torres-Zelada, Robert E Stephenson, Aktan Alpsoy, Benjamin D Anderson, Selene K Swanson

J Cell Sci· January 2019

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Autocrine Fibronectin Inhibits Breast Cancer Metastasis.
Aparna Shinde, Sarah Libring, Aktan Alpsoy, Ammara Abdullah, James A Schaber

Mol Cancer Res· October 2018

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A Novel CRISPR/Cas9-Based Cellular Model to Explore Adenylyl Cyclase and cAMP Signaling.
Monica Soto-Velasquez, Michael P Hayes, Aktan Alpsoy, Emily C Dykhuizen, Val J Watts

Mol Pharmacol· September 2018

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Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes.
Aktan Alpsoy, Emily C Dykhuizen

J Biol Chem· March 2018

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Protein kinase D2 silencing reduced motility of doxorubicin-resistant MCF7 cells.
Aktan Alpsoy, Ufuk Gündüz

Tumour Biol· June 2015

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Etoposide resistance in MCF-7 breast cancer cell line is marked by multiple mechanisms.
Aktan Alpsoy, Seda Yasa, Ufuk Gündüz

Biomed Pharmacother· April 2014

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