Publications by authors named "Akula Balaiah"

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Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.
M V Ramana Reddy, Muralidhar R Mallireddigari, Venkat R Pallela, Stephen C Cosenza, Vinay K Billa, Balaiah Akula

J Med Chem· July 2013

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Hydrothiolation of benzyl mercaptan to arylacetylene: application to the synthesis of (E) and (Z)-isomers of ON 01910·Na (Rigosertib®), a phase III clinical stage anti-cancer agent.
Venkat R Pallela, Muralidhar R Mallireddigari, Stephen C Cosenza, Balaiah Akula, D R C Venkata Subbaiah

Org Biomol Chem· March 2013

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(Z)-1-aryl-3-arylamino-2-propen-1-ones, highly active stimulators of tubulin polymerization: synthesis, structure-activity relationship (SAR), tubulin polymerization, and cell growth inhibition studies.
M V Ramana Reddy, Balaiah Akula, Stephen C Cosenza, Clement M Lee, Muralidhar R Mallireddigari

J Med Chem· June 2012

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Discovery of a clinical stage multi-kinase inhibitor sodium (E)-2-{2-methoxy-5-[(2',4',6'-trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na): synthesis, structure-activity relationship, and biological activity.
M V Ramana Reddy, Padmavathi Venkatapuram, Muralidhar R Mallireddigari, Venkat R Pallela, Stephen C Cosenza, Balaiah Akula

J Med Chem· September 2011

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Design, synthesis and evaluation of (E)-alpha-benzylthio chalcones as novel inhibitors of BCR-ABL kinase.
M V Ramana Reddy, Venkat R Pallela, Stephen C Cosenza, Muralidhar R Mallireddigari, Revathi Patti, Balaiah Akula

Bioorg Med Chem· March 2010

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Glycogen synthase kinase-3 (GSK-3) inhibitory activity and structure-activity relationship (SAR) studies of the manzamine alkaloids. Potential for Alzheimer's disease.
Mark Hamann, Diana Alonso, Ester Martín-Aparicio, Ana Fuertes, M José Pérez-Puerto, Akula Balaiah

J Nat Prod· September 2007

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Syntheses and structures of novel heteroarene-fused coplanar pi-conjugated chromophores.
Ken-Tsung Wong, Teng-Chih Chao, Liang-Chen Chi, Ying-Ying Chu, Akula Balaiah

Org Lett· October 2006

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Modulation of physical properties of Ter(9,9-ditolylfluorene) by backbone-embedded heteroarenes.
Ken-Tsung Wong, Tsyr-Yuan Hwu, Akula Balaiah, Teng-Chih Chao, Fu-Chuan Fang

Org Lett· March 2006

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