Publications by authors named "Alaa Refaat"

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Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target.
Shiekh Tanveer Ahmad, Yiran Li, Jesus Garcia-Lopez, Brian L Gudenas, Jennifer Hadley, Alaa Refaat

Cancer Cell· June 2025

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Preclinical evaluation of the efficacy of an antibody to human SIRPα for cancer immunotherapy in humanized mouse models.
Yasuyuki Saito, Rie Iida-Norita, Tania Afroj, Alaa Refaat, Daisuke Hazama

Front Immunol· January 2024

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Immune Checkpoint Regulators: A New Era Toward Promising Cancer Therapy.
Mohammed Shaaban, Heba Othman, Takwa Ibrahim, Mariam Ali, Mohamed Abdelmoaty, Alaa Refaat

Curr Cancer Drug Targets· July 2021

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An Animal Model That Mimics Human Herpesvirus 6B Pathogenesis.
Bochao Wang, Yasuyuki Saito, Mitsuhiro Nishimura, Zhenxiao Ren, Lidya Handayani Tjan, Alaa Refaat

J Virol· February 2020

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Role of mitochondria in rescuing glycolytically inhibited subpopulation of triple negative but not hormone-responsive breast cancer cells.
Asmaa Reda, Alaa Refaat, Ahmed A Abd-Rabou, Ali Mokhtar Mahmoud, Mohamed Adel

Sci Rep· September 2019

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Prospects for repurposing CNS drugs for cancer treatment.
Mohamed Abdelaleem, Hossam Ezzat, Muhammed Osama, Adel Megahed, Waleed Alaa, Alaa Refaat

Oncol Rev· January 2019

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The Unfolded Protein Response: A Novel Therapeutic Target for Poor Prognostic Mutant Colorectal Cancer.
Nicholas Forsythe, Alaa Refaat, Arman Javadi, Hajrah Khawaja, Jessica-Anne Weir

Mol Cancer Ther· June 2018

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Retrospective screening of microarray data to identify candidate IFN-inducible genes in a HTLV-1 transformed model.
Alaa Refaat, Mohamed Owis, Sherif Abdelhamed, Ikuo Saiki, Hiroaki Sakurai

Oncol Lett· April 2018

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Mechanisms for DNA-damaging agent-induced inactivation of ErbB2 and ErbB3 via the ERK and p38 signaling pathways.
Chul Min Park, Yuki Kawasaki, Alaa Refaat, Hiroaki Sakurai

Oncol Lett· February 2018

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Hyperthermia and radiation reduce the toxic side-effects of bufadienolides for cancer therapy.
Heba Emam, Alaa Refaat, Paras Jawaid, Mati Ur Rehman, Peng Li

Oncol Lett· July 2017

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Bardoxolone-methyl inhibits migration and metabolism in MCF7 cells.
Alaa Refaat, Chathyan Pararasa, Muhammed Arif, James E P Brown, Amtul Carmichael

Free Radic Res· February 2017

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Rapid versus gradual bladder decompression in acute urinary retention.
Mohamed H Etafy, Fatma H Saleh, Cervando Ortiz-Vanderdys, Alaa Hamada, Alaa M Refaat

Urol Ann· January 2017

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Anti-inflammatory effect of cinnamaldehyde in Helicobacter pylori induced gastric inflammation.
Jibran Sualeh Muhammad, Syed Faisal Zaidi, Saeeda Shaharyar, Alaa Refaat, Khan Usmanghani

Biol Pharm Bull· December 2015

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Helicobacter pylori Induces Serine Phosphorylation of EGFR via Novel TAK1-p38 Activation Pathway in an HB-EGF-Independent Manner.
Syed Faisal Zaidi, Alaa Refaat, Yue Zhou, Jibran Sualeh Muhammad, Myoung-Sook Shin

Helicobacter· October 2015

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Inhibition of p38 mitogen-activated protein kinase potentiates the apoptotic effect of berberine/tumor necrosis factor-related apoptosis-inducing ligand combination therapy.
Alaa Refaat, Sherif Abdelhamed, Ikuo Saiki, Hiroaki Sakurai

Oncol Lett· September 2015

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Role of tyrosine kinase-independent phosphorylation of EGFR with activating mutation in cisplatin-treated lung cancer cells.
Alaa Refaat, Aminullah, Yue Zhou, Miho Kawanishi, Rika Tomaru

Biochem Biophys Res Commun· March 2015

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TRAIL combinations: The new 'trail' for cancer therapy (Review).
Alaa Refaat, Ahmed Abd-Rabou, Asmaa Reda

Oncol Lett· May 2014

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Piperine enhances the efficacy of TRAIL-based therapy for triple-negative breast cancer cells.
Sherif Abdelhamed, Satoru Yokoyama, Alaa Refaat, Keisuke Ogura, Hideo Yagita

Anticancer Res· April 2014

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Berberine enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast cancer.
Alaa Refaat, Sherif Abdelhamed, Hideo Yagita, Hiroki Inoue, Satoru Yokoyama

Oncol Lett· September 2013

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Apoptotic cell death by the novel natural compound, cinobufotalin.
Heba Emam, Qing-Li Zhao, Yukihiro Furusawa, Alaa Refaat, Kanwal Ahmed

Chem Biol Interact· September 2012

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Distinct roles of transforming growth factor-beta-activated kinase 1 (TAK1)-c-Rel and interferon regulatory factor 4 (IRF4) pathways in human T cell lymphotropic virus 1-transformed T helper 17 cells producing interleukin-9.
Alaa Refaat, Yue Zhou, Shunsuke Suzuki, Ichiro Takasaki, Keiichi Koizumi

J Biol Chem· June 2011

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Human T cell lymphotropic virus 1 manipulates interferon regulatory signals by controlling the TAK1-IRF3 and IRF4 pathways.
Shunsuke Suzuki, Yue Zhou, Alaa Refaat, Ichiro Takasaki, Keiichi Koizumi

J Biol Chem· February 2010

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Modulation of activation-induced cytidine deaminase by curcumin in Helicobacter pylori-infected gastric epithelial cells.
Syed Faisal Haider Zaidi, Takeshi Yamamoto, Alaa Refaat, Kanwal Ahmed, Hiroaki Sakurai

Helicobacter· December 2009

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