Publications by authors named "Alaattin Kaya"

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mTORC1 activation in presumed classical monocytes: observed correlation with human size variation and neuropsychiatric disease.
Karl Berner, Naci Oz, Alaattin Kaya, Animesh Acharjee, Jon Berner

Aging (Albany NY)· July 2024

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Rapamycin treatment during development extends life span and health span of male mice and .
Anastasia V Shindyapina, Yongmin Cho, Alaattin Kaya, Alexander Tyshkovskiy, José P Castro, Amy Deik, Juozas Gordevicius, Jesse R Poganik, Clary B Clish, Steve Horvath

Sci Adv· September 2022

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Open problems in ageing science: a roadmap for biogerontology.
Angelo Talay, Aleksey V Belikov, Paul Ka Po To, Hamid H Alfatemi, Uri Alon, Alaattin Kaya

Geroscience· November 2025

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Engineering ATP Import in Yeast Uncovers a Synthetic Route to Extend Cellular Lifespan.
Naci Oz, Hetian Su, Vedat Sari, Praveen Patnaik, Rohil Hameed, Alaattin Kaya

bioRxiv· November 2025

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Multiomics from Alzheimer's Brains and Mesenchymal Stem Cell-Derived Extracellular Vesicles Identifies Therapeutic Potential of Specific Subpopulations to Target Mitochondrial Proteostasis.
Morteza Abyadeh, Alaattin Kaya

J Cent Nerv Syst Dis· April 2025

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Short-lived Niemann-Pick type C mice with accelerated brain aging as a novel model for Alzheimer's disease research.
Vikas Anil Gujjala, Morteza Abyadeh, Isaiah Klimek, Alexander Tyshkovskiy, Naci Oz, Alaattin Kaya

Neural Regen Res· April 2025

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Molecular mechanisms of genotype-dependent lifespan variation mediated by caloric restriction: insight from wild yeast isolates.
Samantha McLean, Mitchell Lee, Weiqiang Liu, Rohil Hameed, Vikas Anil Gujjala, Alaattin Kaya

Front Aging· July 2024

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Molecular Mechanisms of Genotype-Dependent Lifespan Variation Mediated by Caloric Restriction: Insight from Wild Yeast Isolates.
Samantha McLean, Mitchell Lee, Weiqiang Liu, Rohil Hameed, Vikas Anil Gujjala, Alaattin Kaya

bioRxiv· May 2024

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A disease similarity approach identifies short-lived Niemann-Pick type C disease mice with accelerated brain aging as a novel mouse model for Alzheimer's disease and aging research.
Vikas Anil Gujjala, Isaiah Klimek, Morteza Abyadeh, Alexander Tyshkovskiy, Naci Oz, Alaattin Kaya

bioRxiv· May 2024

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Application of Multiomics Approach to Investigate the Therapeutic Potentials of Stem Cell-derived Extracellular Vesicle Subpopulations for Alzheimer's Disease.
Morteza Abyadeh, Alaattin Kaya

bioRxiv· May 2024

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Common Molecular Signatures Between Coronavirus Infection and Alzheimer's Disease Reveal Targets for Drug Development.
Morteza Abyadeh, Vijay K Yadav, Alaattin Kaya

J Alzheimers Dis· October 2023

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Large-scale across species transcriptomic analysis identifies genetic selection signatures associated with longevity in mammals.
Weiqiang Liu, Pingfen Zhu, Meng Li, Zihao Li, Yang Yu, Alaattin Kaya

EMBO J· September 2023

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Genetic perturbation of mitochondrial function reveals functional role for specific mitonuclear genes, metabolites, and pathways that regulate lifespan.
Cheryl Zi Jin Phua, Xiaqing Zhao, Lesly Turcios-Hernandez, Morrigan McKernan, Morteza Abyadeh, Alaattin Kaya

Geroscience· August 2023

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Common molecular signatures between coronavirus infection and Alzheimer's disease reveal targets for drug development.
Morteza Abyadeh, Vijay K Yadav, Alaattin Kaya

bioRxiv· June 2023

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The selenoprotein methionine sulfoxide reductase B1 (MSRB1).
Lionel Tarrago, Alaattin Kaya, Hwa-Young Kim, Bruno Manta, Byung-Cheon Lee

Free Radic Biol Med· October 2022

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Evidence that conserved essential genes are enriched for pro-longevity factors.
Naci Oz, Elena M Vayndorf, Mitsuhiro Tsuchiya, Samantha McLean, Lesly Turcios-Hernandez, Alaattin Kaya

Geroscience· August 2022

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Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast.
Alaattin Kaya, Cheryl Zi Jin Phua, Mitchell Lee, Lu Wang, Alexander Tyshkovskiy

Elife· November 2021

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Beaver and Naked Mole Rat Genomes Reveal Common Paths to Longevity.
Xuming Zhou, Qianhui Dou, Guangyi Fan, Quanwei Zhang, Maxwell Sanderford, Alaattin Kaya

Cell Rep· July 2020

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Molecular signatures of aneuploidy-driven adaptive evolution.
Alaattin Kaya, Marco Mariotti, Alexander Tyshkovskiy, Xuming Zhou, Michelle L Hulke

Nat Commun· January 2020

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Sulfate assimilation regulates hydrogen sulfide production independent of lifespan and reactive oxygen species under methionine restriction condition in yeast.
Kyung-Mi Choi, Sorah Kim, Seahyun Kim, Hae Min Lee, Alaattin Kaya

Aging (Albany NY)· June 2019

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Population genomics of finless porpoises reveal an incipient cetacean species adapted to freshwater.
Xuming Zhou, Xuanmin Guang, Di Sun, Shixia Xu, Mingzhou Li, Alaattin Kaya

Nat Commun· April 2018

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Cytochrome peroxidase facilitates the beneficial use of HO in prokaryotes.
Alaattin Kaya, Marco Mariotti, Vadim N Gladyshev

Proc Natl Acad Sci U S A· August 2017

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Age-associated molecular changes are deleterious and may modulate life span through diet.
Sang-Goo Lee, Alaattin Kaya, Andrei S Avanesov, Dmitriy I Podolskiy, Eun Ju Song

Sci Adv· February 2017

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Methionine restriction and life-span control.
Byung Cheon Lee, Alaattin Kaya, Vadim N Gladyshev

Ann N Y Acad Sci· January 2016

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