Publications by authors named "Aladdin Riad"

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characterization of [I]HY-3-24, a selective ligand for the dopamine D3 receptor.
Ji Youn Lee, Ho Young Kim, Paul Martorano, Aladdin Riad, Michelle Taylor

Front Neurosci· April 2024

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Synthesis of bitopic ligands based on fallypride and evaluation of their affinity and selectivity towards dopamine D and D receptors.
Gui-Long Tian, Chia-Ju Hsieh, Michelle Taylor, Ji Youn Lee, Aladdin A Riad

Eur J Med Chem· December 2023

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Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search.
Bieneke Janssen, Guilong Tian, Zsofia Lengyel-Zhand, Chia-Ju Hsieh, Marshall G Lougee, Aladdin Riad

Mol Imaging Biol· August 2023

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Characterization of Sigma-2 Receptor-Specific Binding Sites Using [H]DTG and [I]RHM-4.
Chi-Chang Weng, Aladdin Riad, Brian P Lieberman, Kuiying Xu, Xin Peng

Pharmaceuticals (Basel)· December 2022

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Pre-clinical investigation of astatine-211-parthanatine for high-risk neuroblastoma.
Mehran Makvandi, Minu Samanta, Paul Martorano, Hwan Lee, Sarah B Gitto, Aladdin Riad

Commun Biol· November 2022

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Exploration of Diazaspiro Cores as Piperazine Bioisosteres in the Development of σ2 Receptor Ligands.
Kuiying Xu, Chia-Ju Hsieh, Ji Youn Lee, Aladdin Riad, Nicholas J Izzo

Int J Mol Sci· July 2022

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Screening of σ Receptor Ligands and Evaluation of C-Labeled 6,7-Dimethoxy-2-[4-(4-methoxyphenyl)butan-2-yl]-1,2,3,4-tetrahydroisoquinoline for Potential Use as a σ Receptor Brain PET Tracer.
Ho Young Kim, Ji Youn Lee, Chia-Ju Hsieh, Aladdin Riad, Nicholas J Izzo

J Med Chem· April 2022

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Proceedings from the Fourth International Symposium on σ-2 Receptors: Role in Health and Disease.
Nicholas J Izzo, Martí Colom-Cadena, Aladdin A Riad, Jinbin Xu, Meharvan Singh

eNeuro· June 2021

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Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods.
Chia-Ju Hsieh, Aladdin Riad, Ji Youn Lee, Kristoffer Sahlholm, Kuiying Xu

Biomolecules· April 2021

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Synthesis, binding, and functional properties of tetrahydroisoquinolino-2-alkyl phenones as selective σR/TMEM97 ligands.
Xiao-Yang Xie, Yu-Yun Li, Wen-Hui Ma, Ai-Fang Chen, Yu-Tong Sun, Aladdin Riad

Eur J Med Chem· January 2021

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PARP Theranostic Auger Emitters Are Cytotoxic in BRCA Mutant Ovarian Cancer and Viable Tumors from Ovarian Cancer Patients Enable Ex-Vivo Screening of Tumor Response.
Aladdin Riad, Sarah B Gitto, Hwan Lee, Harrison D Winters, Paul M Martorano

Molecules· December 2020

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The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor Complex Are Responsible for the Cellular Uptake of Aβ42 and Its Protein Aggregates.
Aladdin Riad, Zsofia Lengyel-Zhand, Chenbo Zeng, Chi-Chang Weng, Virginia M-Y Lee

Mol Neurobiol· September 2020

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The Biological Function of Sigma-2 Receptor/TMEM97 and Its Utility in PET Imaging Studies in Cancer.
Chenbo Zeng, Aladdin Riad, Robert H Mach

Cancers (Basel)· July 2020

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PARP-1-Targeted Auger Emitters Display High-LET Cytotoxic Properties In Vitro but Show Limited Therapeutic Utility in Solid Tumor Models of Human Neuroblastoma.
Hwan Lee, Aladdin Riad, Paul Martorano, Adam Mansfield, Minu Samanta

J Nucl Med· June 2020

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Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D Receptor (DR) Ligand Promiscuity across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs).
Sean W Reilly, Aladdin A Riad, Chia-Ju Hsieh, Kristoffer Sahlholm, Daniel A Jacome

J Med Chem· May 2019

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Synthesis and evaluation of an AZD2461 [F]PET probe in non-human primates reveals the PARP-1 inhibitor to be non-blood-brain barrier penetrant.
Sean W Reilly, Laura N Puentes, Alexander Schmitz, Chia-Ju Hsieh, Chi-Chang Weng, Aladdin A Riad

Bioorg Chem· March 2019

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TMEM97 and PGRMC1 do not mediate sigma-2 ligand-induced cell death.
Chenbo Zeng, Chi-Chang Weng, Mark E Schneider, Laura Puentes, Aladdin Riad

Cell Death Discov· January 2019

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Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex.
Aladdin Riad, Chenbo Zeng, Chi-Chang Weng, Harrison Winters, Kuiying Xu

Sci Rep· November 2018

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Protein disulfide isomerase does not act as an unfoldase in the disassembly of cholera toxin.
Patrick Cherubin, Jessica Guyette, Michael Taylor, Morgan O'Donnell, Laura Herndon, Aladdin Riad

Biosci Rep· October 2018

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A Novel Mechanism for Atherosclerotic Calcification: Potential Resolution of the Oxidation Paradox.
Aladdin Riad, Chandrakala Aluganti Narasimhulu, Pragney Deme, Sampath Parthasarathy

Antioxid Redox Signal· August 2018

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Primary prevention of atherosclerosis by pretreatment of low-density lipoprotein receptor knockout mice with sesame oil and its aqueous components.
Chandrakala Aluganti Narasimhulu, Kathryn Young Burge, Mitsushita Doomra, Aladdin Riad, Sampath Parthasarathy

Sci Rep· August 2018

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Sesame Oil and an Aqueous Extract Derived from Sesame Oil Enhance Regression of Preexisting Atherosclerotic Lesions in Low-Density Lipoprotein Receptor Knockout Mice.
Chandrakala Aluganti Narasimhulu, Aladdin Riad, Sampath Parthasarathy

J Med Food· July 2018

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Inflammatory Diseases of the Gut.
Michael Rohr, Chandrakala Aluganti Narasimhulu, Dhara Sharma, Mitsushita Doomra, Aladdin Riad

J Med Food· February 2018

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Alzheimer's Disease-Current Status and Future Directions.
Deepshikha Bhardwaj, Connie Mitra, Chandrakala Aluganti Narasimhulu, Aladdin Riad, Mitsushita Doomra

J Med Food· December 2017

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Atherosclerosis--do we know enough already to prevent it?
Chandrakala Aluganti Narasimhulu, Irene Fernandez-Ruiz, Krithika Selvarajan, Xeuting Jiang, Bhaswati Sengupta, Aladdin Riad

Curr Opin Pharmacol· April 2016

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