Publications by authors named "Alain Bruno"

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Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors.
Csaba Weber, Melinda Sipos, Attila Paczal, Balazs Balint, Vilibald Kun, Alain Bruno

J Med Chem· May 2021

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Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor.
Zoltan Szlavik, Marton Csekei, Attila Paczal, Zoltan B Szabo, Szabolcs Sipos, Alain Bruno

J Med Chem· November 2020

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S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.
Patrick Casara, James Davidson, Audrey Claperon, Gaëtane Le Toumelin-Braizat, Meike Vogler, Alain Bruno

Oncotarget· April 2018

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The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
András Kotschy, Zoltán Szlavik, James Murray, James Davidson, Ana Leticia Maragno, Alain Bruno

Nature· October 2016

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S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.
Mike F Burbridge, Céline J Bossard, Carine Saunier, Imre Fejes, Alain Bruno

Mol Cancer Ther· September 2013

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[Contribution to new therapeutics against colorectal cancer: the CReMEC initiative].
Alain Bruno

Med Sci (Paris)· March 2013

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Characterization of a large panel of patient-derived tumor xenografts representing the clinical heterogeneity of human colorectal cancer.
Sylvia Julien, Ana Merino-Trigo, Ludovic Lacroix, Marc Pocard, Diane Goéré, Alain Bruno

Clin Cancer Res· October 2012

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Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells.
Florence Sancier, Aurélie Dumont, Audrey Sirvent, Ludmilla Paquay de Plater, Thomas Edmonds, Alain Bruno

PLoS One· February 2011

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