Publications by authors named "Alain Gey"

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Soluble TIM-3, likely produced by myeloid cells, predicts resistance to immune checkpoint inhibitors in metastatic clear cell renal cell carcinoma.
Ivan Pourmir, Nadine Benhamouda, Thi Tran, Hugo Roux, Joséphine Pineau, Alain Gey

J Exp Clin Cancer Res· February 2025

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Differential predictive value of resident memory CD8T cell subpopulations in patients with non-small-cell lung cancer treated by immunotherapy.
Léa Paolini, Thi Tran, Stéphanie Corgnac, Jean-Philippe Villemin, Marie Wislez, Alain Gey

J Immunother Cancer· December 2024

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Increased levels of GM-CSF and CXCL10 and low CD8 memory stem T Cell count are markers of immunosenescence and severe COVID-19 in older people.
Johanne Poisson, Carine El-Sissy, Arnaud Serret-Larmande, Nikaïa Smith, Morgane Lebraud, Alain Gey

Immun Ageing· May 2024

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Enteral citrulline supplementation versus placebo on SOFA score on day 7 in mechanically ventilated critically ill patients: the IMMUNOCITRE randomized clinical trial.
Jean-Marc Tadié, Clara Locher, Adel Maamar, Jean Reignier, Pierre Asfar, Alain Gey

Crit Care· October 2023

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Plasma CD27, a Surrogate of the Intratumoral CD27-CD70 Interaction, Correlates with Immunotherapy Resistance in Renal Cell Carcinoma.
Nadine Benhamouda, Ikuan Sam, Nicolas Epaillard, Alain Gey, Letuan Phan

Clin Cancer Res· November 2022

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CXCR6 expressing T cells: Functions and role in the control of tumors.
Nesrine Mabrouk, Thi Tran, Ikuan Sam, Ivan Pourmir, Nadège Gruel, Alain Gey

Front Immunol· November 2022

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Decrease of Pro-Angiogenic Monocytes Predicts Clinical Response to Anti-Angiogenic Treatment in Patients with Metastatic Renal Cell Carcinoma.
Stephane Oudard, Nadine Benhamouda, Bernard Escudier, Patrice Ravel, Thi Tran, Alain Gey

Cells· December 2021

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TIM-3 Dictates Functional Orientation of the Immune Infiltrate in Ovarian Cancer.
Jitka Fucikova, Jana Rakova, Michal Hensler, Lenka Kasikova, Lucie Belicova, Alain Gey

Clin Cancer Res· August 2019

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Absolute numbers of regulatory T cells and neutrophils in corticosteroid-free patients are predictive for response to bevacizumab in recurrent glioblastoma patients.
Véronique Quillien, Antoine F Carpentier, Alain Gey, Tony Avril, Eric Tartour

Cancer Immunol Immunother· June 2019

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High Therapeutic Efficacy of a New Survivin LSP-Cancer Vaccine Containing CD4 and CD8 T-Cell Epitopes.
Fanny Onodi, Chahrazed Maherzi-Mechalikh, Alice Mougel, Nadine Ben Hamouda, Charlotte Taboas, Alain Gey

Front Oncol· November 2018

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[Tim-3: a novel biomarker and therapeutic target in oncology].
Clémence Granier, Alain Gey, Charles Dariane, Arnaud Mejean, Marc-Olivier Timsit

Med Sci (Paris)· March 2018

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Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells.
Clémence Granier, Emeline Vinatier, Elia Colin, Marion Mandavit, Charles Dariane, Alain Gey

J Vis Exp· February 2018

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Mechanisms of action and rationale for the use of checkpoint inhibitors in cancer.
Clemence Granier, Eleonore De Guillebon, Charlotte Blanc, Helene Roussel, Cecile Badoual, Alain Gey

ESMO Open· July 2017

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Tim-3 Expression on Tumor-Infiltrating PD-1CD8 T Cells Correlates with Poor Clinical Outcome in Renal Cell Carcinoma.
Clémence Granier, Charles Dariane, Pierre Combe, Virginie Verkarre, Saïk Urien, Alain Gey

Cancer Res· March 2017

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Composite biomarkers defined by multiparametric immunofluorescence analysis identify ALK-positive adenocarcinoma as a potential target for immunotherapy.
Hélène Roussel, Eléonore De Guillebon, Lucie Biard, Marion Mandavit, Laure Gibault, Alain Gey

Oncoimmunology· February 2017

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A Therapeutic Her2/neu Vaccine Targeting Dendritic Cells Preferentially Inhibits the Growth of Low Her2/neu-Expressing Tumor in HLA-A2 Transgenic Mice.
Thi Tran, Mariana O Diniz, Estelle Dransart, Alain Gey, Nathalie Merillon

Clin Cancer Res· August 2016

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IL-15 Trans-Signaling with the Superagonist RLI Promotes Effector/Memory CD8+ T Cell Responses and Enhances Antitumor Activity of PD-1 Antagonists.
Mélanie Desbois, Pauline Le Vu, Clélia Coutzac, Elie Marcheteau, Coralie Béal, Alain Gey

J Immunol· July 2016

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Clinical validation of IFNγ/IL-10 and IFNγ/IL-2 FluoroSpot assays for the detection of Tr1 T cells and influenza vaccine monitoring in humans.
Anne Chauvat, Nadine Benhamouda, Alain Gey, Francois M Lemoine, Staffan Paulie

Hum Vaccin Immunother· January 2015

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Arginine administration to critically ill patients with a low nitric oxide fraction in the airways: a pilot study.
Jean-Marc Tadié, Luc Cynober, Vincent Peigne, Aurore Caumont-Prim, Nathalie Neveux, Alain Gey

Intensive Care Med· September 2013

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[PD-1 and PDL-1 expression in cancer: significance and prognostic value].
Cécile Badoual, Pierre Combe, Alain Gey, Clémence Granier, Hélène Roussel

Med Sci (Paris)· September 2013

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Mucosal imprinting of vaccine-induced CD8⁺ T cells is crucial to inhibit the growth of mucosal tumors.
Federico Sandoval, Magali Terme, Mevyn Nizard, Cécile Badoual, Michel-Francis Bureau, Alain Gey

Sci Transl Med· February 2013

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PD-1-expressing tumor-infiltrating T cells are a favorable prognostic biomarker in HPV-associated head and neck cancer.
Cécile Badoual, Stéphane Hans, Nathalie Merillon, Cordélia Van Ryswick, Patrice Ravel, Alain Gey

Cancer Res· January 2013

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A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens.
Helene Pere, Yves Montier, Jagadeesh Bayry, Francoise Quintin-Colonna, Nathalie Merillon, Alain Gey

Blood· November 2011

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Better understanding tumor-host interaction in head and neck cancer to improve the design and development of immunotherapeutic strategies.
Cécile Badoual, Federico Sandoval, Helene Pere, Stephane Hans, Alain Gey

Head Neck· July 2010

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The soluble alpha chain of interleukin-15 receptor: a proinflammatory molecule associated with tumor progression in head and neck cancer.
Cécile Badoual, Grégory Bouchaud, Nour El Houda Agueznay, Erwan Mortier, Stéphane Hans, Alain Gey

Cancer Res· May 2008

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