Publications by authors named "Alain Wagner"

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Stoichiometric Antibody-Polymer-Drug Conjugate for Effective Low-Dose Treatment of Breast Cancer.
Victor Lehot, Ondřej Lidický, Julien Most, Marc Nothisen, Stéphane Erb, Alain Wagner

Biomacromolecules· November 2025

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Antibody-Vincristine Conjugates as Potent Anticancer Therapeutic Agents.
Agathe Boos, Julien Most, Héloïse Cahuzac, Louis Moreira da Silva, François Daubeuf, Alain Wagner

J Med Chem· January 2025

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Protocol to generate, purify, and analyze antibody-oligonucleotide conjugates from off-the-shelf antibodies.
Tony Rady, Victor Lehot, Julien Most, Stephane Erb, Sarah Cianferani, Alain Wagner

STAR Protoc· December 2024

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Retinoids Molecular Probes by Late-stage Azide Insertion - Functional Tools to Decrypt Retinoid Metabolism.
Jessica Coulleray, Alexia Kindler, Mohamad Rima, Héloïse Cahuzac, Natacha Rochel, Alain Wagner

Chembiochem· October 2024

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Supramolecular Bioconjugation Strategy for Antibody-Targeted Delivery of siRNA.
Manon Ripoll, Héloïse Cahuzac, Igor Dovgan, Sylvain Ursuegui, Patrick Neuberg, Alain Wagner

Bioconjug Chem· September 2024

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Site-Selective Protein Conjugation by a Multicomponent Ugi Reaction.
Ilias Koutsopetras, Valentine Vaur, Rania Benazza, Hélène Diemer, Charlotte Sornay, Alain Wagner

Chemistry· March 2024

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Targeted delivery of immune-stimulating bispecific RNA, inducing apoptosis and anti-tumor immunity in cancer cells.
Tony Rady, Stéphane Erb, Safia Deddouche-Grass, Renaud Morales, Guilhem Chaubet, Alain Wagner

iScience· March 2024

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Drug upgrade: A complete methodology from old drug to new chemical entities using Nematic Protein Organization Technique.
Judith Eschbach, Alain Wagner, Corinne Beahr, Akkiz Bekel, Anne-Sophie Korganow

Drug Dev Res· February 2024

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Reinvestigation of the Automated Synthesis of Stoichiometrically Conjugated Antibodies to Access High Molecular Weight Payloads and Multiplexed Conjugation via an In-Solution Trans-Tagging Process.
Victor Lehot, Ondřej Lidický, Julien Most, Stéphane Erb, Igor Dovgan, Alain Wagner

ACS Omega· October 2023

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Microfluidic Droplet Stabilization via SPAAC Promoted Antibody Conjugation at the Water/Oil Interface.
Robin Dufossez, Marie-Pierre Krafft, Sylvain Ursuegui, Michel Mosser, Safae Mouftakhir, Alain Wagner

ACS Appl Mater Interfaces· September 2023

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Targeted Anticancer Agent with Original Mode of Action Prepared by Supramolecular Assembly of Antibody Oligonucleotide Conjugates and Cationic Nanoparticles.
Victor Lehot, Patrick Neuberg, Manon Ripoll, François Daubeuf, Stéphane Erb, Alain Wagner

Pharmaceutics· June 2023

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Droplet Surface Immunoassay by Relocation (D-SIRe) for High-Throughput Analysis of Cytosolic Proteins at the Single-Cell Level.
Robin Dufossez, Sylvain Ursuegui, Stephanie Baudrey, Ketty Pernod, Safae Mouftakhir, Alain Wagner

Anal Chem· March 2023

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A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity.
Tony Rady, Lorenzo Turelli, Marc Nothisen, Elisabetta Tobaldi, Stéphane Erb, Alain Wagner

Bioconjug Chem· October 2022

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An overview of chemo- and site-selectivity aspects in the chemical conjugation of proteins.
Charlotte Sornay, Valentine Vaur, Alain Wagner, Guilhem Chaubet

R Soc Open Sci· January 2022

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Manniindole, an indole derivative from the roots of and combined antischistosomal and enzymatic activities.
Josette Linda Toussi Matchi, Diderot Tchamo Noungoue, Isabelle Kuhn, Jérôme Boissier, Jean Claude Tchouankeu, Alain Wagner

Nat Prod Res· December 2021

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Bicyclo[6.1.0]nonyne carboxylic acid for the production of stable molecular probes.
Tony Rady, Michel Mosser, Marc Nothisen, Stephane Erb, Igor Dovgan, Alain Wagner

RSC Adv· November 2021

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Plasma induced acceleration and selectivity in strain-promoted azide-alkyne cycloadditions.
David Warther, Enes Dursun, Marion Recher, Sylvain Ursuegui, Michel Mosser, Alain Wagner

Org Biomol Chem· June 2021

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Non-specific interactions of antibody-oligonucleotide conjugates with living cells.
Victor Lehot, Isabelle Kuhn, Marc Nothisen, Stéphane Erb, Sergii Kolodych, Alain Wagner

Sci Rep· March 2021

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Investigating Ugi/Passerini Multicomponent Reactions for the Site-Selective Conjugation of Native Trastuzumab*.
Charlotte Sornay, Steve Hessmann, Stéphane Erb, Igor Dovgan, Anthony Ehkirch, Alain Wagner

Chemistry· November 2020

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Ethynylation of Cysteine Residues: From Peptides to Proteins in Vitro and in Living Cells.
Romain Tessier, Raj Kumar Nandi, Brendan G Dwyer, Daniel Abegg, Charlotte Sornay, Alain Wagner

Angew Chem Int Ed Engl· June 2020

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On the use of DNA as a linker in antibody-drug conjugates: synthesis, stability and in vitro potency.
Igor Dovgan, Anthony Ehkirch, Victor Lehot, Isabelle Kuhn, Oleksandr Koniev, Alain Wagner

Sci Rep· May 2020

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Automated linkage of proteins and payloads producing monodisperse conjugates.
Igor Dovgan, Alexandre Hentz, Oleksandr Koniev, Anthony Ehkirch, Steve Hessmann, Alain Wagner

Chem Sci· January 2020

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Antibody-Oligonucleotide Conjugates as Therapeutic, Imaging, and Detection Agents.
Igor Dovgan, Oleksandr Koniev, Sergii Kolodych, Alain Wagner

Bioconjug Chem· October 2019

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Design and evaluation of ionizable peptide amphiphiles for siRNA delivery.
Patrick Neuberg, Alain Wagner, Jean-Serge Remy, Antoine Kichler

Int J Pharm· July 2019

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Sydnone-based turn-on fluorogenic probes for no-wash protein labeling and in-cell imaging.
Lucie Plougastel, Manas R Pattanayak, Margaux Riomet, Sarah Bregant, Antoine Sallustrau, Alain Wagner

Chem Commun (Camb)· April 2019

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