Publications by authors named "Alain van Gool"

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Effect of Pegcetacoplan on Aqueous Humor Proteome in Geographic Atrophy: A Prospective Exploration.
Omer Trivizki, Charles C Wykoff, Magda A Smoor, David Rabinovitch, Avery Zhou, Alain J van Gool

Invest Ophthalmol Vis Sci· December 2025

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Advances in multiple myeloma blood-based monitoring and its clinical applications.
Anastasia Tzasta, Charissa Wijnands, Kim Baalman, Alain J van Gool, Sonja Zweegman

Crit Rev Clin Lab Sci· November 2025

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Extreme MetaboHealth scores in three cohort studies associate with plasma protein markers for inflammation and cholesterol transport.
Daniele Bizzarri, Erik B van den Akker, Marcel J T Reinders, René Pool, Marian Beekman, Alain J van Gool

Immun Ageing· September 2025

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Monitoring M-Protein, Therapeutic Antibodies, and Polyclonal Antibodies in a Multiparametric Mass Spectrometry Assay Provides Insight into Therapy Response Kinetics in Patients with Multiple Myeloma.
Charissa Wijnands, Peter G A Karel, Jolein Gloerich, Gad Armony, Anastasia Tzasta, Alain J van Gool

Pharmaceutics· January 2025

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A rare homozygous variant causes adult-onset diabetes.
Roel Tans, Tine Glendorf, Antonius E van Herwaarden, Hanka Venselaar, Danique M H van Rijswijck, Alain van Gool

BMJ Open Diabetes Res Care· December 2024

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FAIR Data Cube, a FAIR data infrastructure for integrated multi-omics data analysis.
Xiaofeng Liao, Thomas H A Ederveen, Anna Niehues, Casper de Visser, Junda Huang, Alain J van Gool

J Biomed Semantics· December 2024

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An automated workflow based on data independent acquisition for practical and high-throughput personalized assay development and minimal residual disease monitoring in multiple myeloma patients.
Charissa Wijnands, Gad Armony, Somayya Noori, Jolein Gloerich, Vincent Bonifay, Alain J van Gool

Clin Chem Lab Med· November 2024

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Plasma glycoproteomics delivers high-specificity disease biomarkers by detecting site-specific glycosylation abnormalities.
Hans J C T Wessels, Purva Kulkarni, Maurice van Dael, Anouk Suppers, Esther Willems, Alain J van Gool

J Adv Res· July 2024

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N-linked glycosylation of the M-protein variable region: glycoproteogenomics reveals a new layer of personalized complexity in multiple myeloma.
Pieter Langerhorst, Melissa Baerenfaenger, Purva Kulkarni, Simon Nadal, Charissa Wijnands, Alain J van Gool

Clin Chem Lab Med· July 2024

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Maximizing Glycoproteomics Results through an Integrated Parallel Accumulation Serial Fragmentation Workflow.
Melissa Baerenfaenger, Merel A Post, Fokje Zijlstra, Alain J van Gool, Dirk J Lefeber

Anal Chem· June 2024

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M-protein diagnostics in multiple myeloma patients using ultra-sensitive targeted mass spectrometry and an off-the-shelf calibrator.
Charissa Wijnands, Pieter Langerhorst, Somayya Noori, Jenneke Keizer-Garritsen, Hans J C T Wessels, Alain J van Gool

Clin Chem Lab Med· February 2024

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A multi-omics data analysis workflow packaged as a FAIR Digital Object.
Anna Niehues, Casper de Visser, Fiona A Hagenbeek, Purva Kulkarni, René Pool, Alain J van Gool

Gigascience· January 2024

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Ten quick tips for building FAIR workflows.
Casper de Visser, Lennart F Johansson, Purva Kulkarni, Hailiang Mei, Pieter Neerincx, Alain J van Gool

PLoS Comput Biol· September 2023

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Impact of infection on proteome-wide glycosylation revealed by distinct signatures for bacterial and viral pathogens.
Esther Willems, Jolein Gloerich, Anouk Suppers, Michiel van der Flier, Lambert P van den Heuvel, Alain J van Gool

iScience· August 2023

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Circulating FGF21 Concentration, Fasting Plasma Glucose, and the Risk of Type 2 Diabetes: Results From the PREVEND Study.
Adrian Post, Wendy A Dam, Sara Sokooti, Dion Groothof, Jolein Gloerich, Alain J van Gool

J Clin Endocrinol Metab· May 2023

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The GlycoPaSER Prototype as a Real-Time N-Glycopeptide Identification Tool Based on the PaSER Parallel Computing Platform.
Gad Armony, Sven Brehmer, Tharan Srikumar, Lennard Pfennig, Fokje Zijlstra, Alain J van Gool

Int J Mol Sci· April 2023

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Primary Focal Segmental Glomerulosclerosis Plasmas Increase Lipid Droplet Formation and Perilipin-2 Expression in Human Podocytes.
Dirk J W den Braanker, Rutger J H Maas, Guido van Mierlo, Naomi M J Parr, Marinka Bakker-van Bebber, Alain J van Gool

Int J Mol Sci· December 2022

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Tackling the translational challenges of multi-omics research in the realm of European personalised medicine: A workshop report.
Emanuela Oldoni, Gary Saunders, Florence Bietrix, Maria Laura Garcia Bermejo, Anna Niehues, Alain J van Gool

Front Mol Biosci· October 2022

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Fasting Proinsulin Independently Predicts Incident Type 2 Diabetes in the General Population.
Sara Sokooti, Wendy A Dam, Tamas Szili-Torok, Jolein Gloerich, Alain J van Gool

J Pers Med· July 2022

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Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies.
Anna Niehues, Daniele Bizzarri, Marcel J T Reinders, P Eline Slagboom, Alain J van Gool

BMC Genomics· July 2022

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Site-Specific, Platform-Based Conjugation Strategy for the Synthesis of Dual-Labeled Immunoconjugates for Bimodal PET/NIRF Imaging of HER2-Positive Tumors.
Pierre Adumeau, René Raavé, Milou Boswinkel, Sandra Heskamp, Hans J C T Wessels, Alain J van Gool

Bioconjug Chem· March 2022

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Multiple Myeloma Minimal Residual Disease Detection: Targeted Mass Spectrometry in Blood vs Next-Generation Sequencing in Bone Marrow.
Pieter Langerhorst, Somayya Noori, Marina Zajec, Yolanda B De Rijke, Jolein Gloerich, Alain J van Gool

Clin Chem· November 2021

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Semi-Quantitative Multiplex Profiling of the Complement System Identifies Associations of Complement Proteins with Genetic Variants and Metabolites in Age-Related Macular Degeneration.
I Erkin Acar, Esther Willems, Eveline Kersten, Jenneke Keizer-Garritsen, Else Kragt, Alain J van Gool

J Pers Med· November 2021

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Understanding the increased risk of infections in diabetes: innate and adaptive immune responses in type 1 diabetes.
Anna W M Janssen, Rinke Stienstra, Martin Jaeger, Alain J van Gool, Leo A B Joosten

Metabolism· August 2021

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Metabolomics-Based Screening of Inborn Errors of Metabolism: Enhancing Clinical Application with a Robust Computational Pipeline.
Brechtje Hoegen, Alan Zammit, Albert Gerritsen, Udo F H Engelke, Steven Castelein, Alain J van Gool

Metabolites· August 2021

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