Publications by authors named "Alan Cockayne"

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Colonisation Factor CD0873, an Attractive Oral Vaccine Candidate against .
Cansu Karyal, Jaime Hughes, Michelle L Kelly, Jeni C Luckett, Philip V Kaye, Alan Cockayne

Microorganisms· February 2021

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Generation of a fully erythromycin-sensitive strain of Clostridioides difficile using a novel CRISPR-Cas9 genome editing system.
Patrick Ingle, Daphne Groothuis, Peter Rowe, He Huang, Alan Cockayne

Sci Rep· May 2019

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What's a SNP between friends: The influence of single nucleotide polymorphisms on virulence and phenotypes of Clostridium difficile strain 630 and derivatives.
Mark M Collery, Sarah A Kuehne, Shonna M McBride, Michelle L Kelly, Marc Monot, Alan Cockayne

Virulence· August 2017

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Antibiotic Spider Silk: Site-Specific Functionalization of Recombinant Spider Silk Using "Click" Chemistry.
David Harvey, Philip Bardelang, Sara L Goodacre, Alan Cockayne, Neil R Thomas

Adv Mater· March 2017

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Improving the reproducibility of the NAP1/B1/027 epidemic strain R20291 in the hamster model of infection.
Michelle L Kelly, Yen Kuan Ng, Stephen T Cartman, Mark M Collery, Alan Cockayne

Anaerobe· June 2016

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Pathogenesis of Clostridium difficile Infection and Its Potential Role in Inflammatory Bowel Disease.
Tanya M Monaghan, Alan Cockayne, Yashwant R Mahida

Inflamm Bowel Dis· August 2015

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Development of a heptaplex PCR assay for identification of Staphylococcus aureus and CoNS with simultaneous detection of virulence and antibiotic resistance genes.
Charles Emeka Okolie, Karl G Wooldridge, David P J Turner, Alan Cockayne, Richard James

BMC Microbiol· August 2015

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Development of a new pentaplex real-time PCR assay for the identification of poly-microbial specimens containing Staphylococcus aureus and other staphylococci, with simultaneous detection of staphylococcal virulence and methicillin resistance markers.
Charles E Okolie, Karl G Wooldridge, David P Turner, Alan Cockayne, Richard James

Mol Cell Probes· June 2015

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Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors.
Ewan J Murray, Rebecca C Crowley, Alex Truman, Simon R Clarke, James A Cottam, Alan Cockayne

J Med Chem· March 2014

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Importance of toxin A, toxin B, and CDT in virulence of an epidemic Clostridium difficile strain.
Sarah A Kuehne, Mark M Collery, Michelle L Kelly, Stephen T Cartman, Alan Cockayne

J Infect Dis· January 2014

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Engineering of the LukS-PV and LukF-PV subunits of Staphylococcus aureus Panton-Valentine leukocidin for diagnostic and therapeutic applications.
Charles Emeka Okolie, Alan Cockayne, Christopher Penfold, Richard James

BMC Biotechnol· November 2013

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Combinatorial discovery of polymers resistant to bacterial attachment.
Andrew L Hook, Chien-Yi Chang, Jing Yang, Jeni Luckett, Alan Cockayne

Nat Biotechnol· September 2012

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Fur is required for the activation of virulence gene expression through the induction of the sae regulatory system in Staphylococcus aureus.
Miranda Johnson, Mrittika Sengupta, Joanne Purves, Emma Tarrant, Peter H Williams, Alan Cockayne

Int J Med Microbiol· January 2011

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Comparison of the regulation, metabolic functions, and roles in virulence of the glyceraldehyde-3-phosphate dehydrogenase homologues gapA and gapB in Staphylococcus aureus.
Joanne Purves, Alan Cockayne, Peter C E Moody, Julie A Morrissey

Infect Immun· December 2010

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The role of toxin A and toxin B in Clostridium difficile infection.
Sarah A Kuehne, Stephen T Cartman, John T Heap, Michelle L Kelly, Alan Cockayne

Nature· October 2010

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The emergence of 'hypervirulence' in Clostridium difficile.
Stephen T Cartman, John T Heap, Sarah A Kuehne, Alan Cockayne, Nigel P Minton

Int J Med Microbiol· August 2010

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Iron-regulated biofilm formation in Staphylococcus aureus Newman requires ica and the secreted protein Emp.
Miranda Johnson, Alan Cockayne, Julie A Morrissey

Infect Immun· April 2008

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Control of bacterial aggregation by thermoresponsive glycopolymers.
George Pasparakis, Alan Cockayne, Cameron Alexander

J Am Chem Soc· September 2007

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Crystal structure of the heme-IsdC complex, the central conduit of the Isd iron/heme uptake system in Staphylococcus aureus.
Katherine H Sharp, Sabine Schneider, Alan Cockayne, Max Paoli

J Biol Chem· April 2007

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N-acylhomoserine lactones antagonize virulence gene expression and quorum sensing in Staphylococcus aureus.
Saara Qazi, Barry Middleton, Siti Hanna Muharram, Alan Cockayne, Philip Hill

Infect Immun· February 2006

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Iron-responsive regulation of biofilm formation in staphylococcus aureus involves fur-dependent and fur-independent mechanisms.
Miranda Johnson, Alan Cockayne, Peter H Williams, Julie A Morrissey

J Bacteriol· December 2005

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The staphylococcal ferritins are differentially regulated in response to iron and manganese and via PerR and Fur.
Julie A Morrissey, Alan Cockayne, Kirsty Brummell, Paul Williams

Infect Immun· February 2004

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Synthesis and deformylation of Staphylococcus aureus delta-toxin are linked to tricarboxylic acid cycle activity.
Greg A Somerville, Alan Cockayne, Manuela Dürr, Andreas Peschel, Michael Otto

J Bacteriol· November 2003

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Side-chain-to-tail thiolactone peptide inhibitors of the staphylococcal quorum-sensing system.
R John Scott, Lu-Yun Lian, S Hanna Muharram, Alan Cockayne, Stewart J Wood

Bioorg Med Chem Lett· August 2003

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NapA protects Helicobacter pylori from oxidative stress damage, and its production is influenced by the ferric uptake regulator.
Clare Cooksley, Peter J Jenks, Andrew Green, Alan Cockayne, Robert P H Logan

J Med Microbiol· June 2003

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