Publications by authors named "Alan D Irvine"

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Triggers, Drivers, and Lids: Uncovering the Mechanistic Differentiators between IL-4- and IL-13-Targeted mAbs.
Karina M Forde, Alan D Irvine

J Invest Dermatol· December 2025

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The VASCERN-VASCA diagnostic and management pathways for kaposiform hemangioendothelioma.
Paolo Gasparella, Emir Q Haxhija, Rune Andersen, Maria Barea, Eulalia Baselga, Alan D Irvine

Eur J Pediatr· December 2025

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P19 A rare case of PHOAR2-enteropathy syndrome (PHOAR2E; previously known as pachydermoperiostosis) with a causal variant in the SLCO2A1 gene.
Cristina Grechin, Alan D Irvine, Natasha Jordan, Bairbre Wynne

Br J Dermatol· December 2025

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Towards Personalised Therapy in Chronic Spontaneous Urticaria: Advancing From Endotype to Clinical Response.
Katie Ridge, Rizwan Ahmad, Barry Moran, Cliona O'Farrelly, Jean Dunne, Alan D Irvine

Clin Exp Allergy· November 2025

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Efficacy and Safety of Upadacitinib in Patients With Moderate-to-Severe Atopic Dermatitis: Phase 3 Randomized Clinical Trial Results Through 140 Weeks.
Alan D Irvine, Vimal H Prajapati, Emma Guttman-Yassky, Eric L Simpson, Kim A Papp

Am J Clin Dermatol· November 2025

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The Texture of Resilience: A Darier Disease Perspective.
Fiona Sexton, Seán O'Malley, Alan D Irvine

Br J Dermatol· November 2025

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Safety of upadacitinib in atopic dermatitis in randomized clinical trials across 6 years.
Christopher G Bunick, Alan D Irvine, Jonathan I Silverberg, Emma Guttman-Yassky, Mona Shahriari

J Eur Acad Dermatol Venereol· November 2025

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Methotrexate and ciclosporin both reduce levels of circulating interleukin (IL)-4 and IL-13 expressing CD4+ memory T cells in childhood atopic dermatitis.
Anton Olsson, Kathryn Steel, Rachael Cooper, Ashley P Jones, Kaitlyn R Chan, Alan D Irvine

Clin Exp Dermatol· October 2025

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Safety Profile of Upadacitinib: Descriptive Analysis in Over 27,000 Patient-Years Across Rheumatoid Arthritis, Psoriatic Arthritis, Axial Spondyloarthritis, Atopic Dermatitis, and Inflammatory Bowel Disease.
Gerd R Burmester, Atul Deodhar, Alan D Irvine, Remo Panaccione, Kevin L Winthrop

Adv Ther· October 2025

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Disproportionality analysis highlights paradoxical psoriasis as a clinically significant class effect of tumor necrosis-α inhibitors in pediatric populations.
Fiona Lynch, Alan D Irvine

Pediatr Res· October 2025

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International multicenter case series of gestational dupilumab exposure in the treatment of atopic dermatitis: Maternal complications and fetal outcomes.
Ajay S Dulai, Emi M Murase, Gianluca Avallone, Silvia Mariel Ferrucci, Angelo Valerio Marzano, Alan D Irvine

J Am Acad Dermatol· October 2025

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Toward the Next Generation of In Silico Modeling of Dynamic Host-Microbiota Interactions in the Skin.
Jamie Lee, Hiu Lam Athena Wu, Ahmad A Mannan, Yuumi Nakamura, Masayuki Amagai, Alan D Irvine

JID Innov· September 2025

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Effect of Topical Corticosteroid Treatment on microRNA Expression in Infants with Atopic Dermatitis.
Janna Nousbeck, Maeve A McAleer, Elaine M Kenny, Alan D Irvine

JID Innov· September 2025

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Myeloid and Mast Cell Progenitors Are Elevated in Atopic Dermatitis.
Katie Ridge, Barry Moran, Mark A Little, Cliona O'Farrelly, Jean Dunne, Alan D Irvine

JID Innov· September 2025

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Ultrastrong adhesion to human skin: Calcium as a key regulator of noncovalent interactions.
Constance Chantraine, Priscila S F C Gomes, Marion Mathelié-Guinlet, Diego E B Gomes, Zhiyong Zheng, Alan D Irvine

Sci Adv· September 2025

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Implementing Federated Analysis Using DataSHIELD in the DREAM TO TREAT Atopic Dermatitis Registries Collaboration.
Niels Steen Krogh, David Prieto-Merino, Bolaji Coker, Thomas Birkner, Ahmet Akkoc, Alan D Irvine

J Invest Dermatol· September 2025

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Gene-environment interaction analysis in atopic eczema: evidence from large population datasets and modelling .
Marie Standl, Ashley Budu-Aggrey, Luke J Johnston, Martina S Elias, S Hasan Arshad, Alan D Irvine

medRxiv· September 2025

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Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions.
Marjolein S de Bruin-Weller, Celeste M Boesjes, Roselie A Achten, Lisa A Beck, Alan D Irvine

Allergy· September 2025

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Caution regarding interpretation of trends for the global burden of atopic dermatitis and asthma.
Sheng-Pei Wang, Elisha Myers, Bernd W M Arents, Carsten Flohr, Alan D Irvine

Br J Dermatol· September 2025

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Gene-Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies.
Marie Standl, Ashley Budu-Aggrey, Luke J Johnston, Martina S Elias, S Hasan Arshad, Alan D Irvine

Allergy· August 2025

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Two-Year Efficacy and Safety of Lebrikizumab in Patients with Moderate-to-Severe Atopic Dermatitis: A Long-Term Extension (ADjoin).
Emma Guttman-Yassky, Stephan Weidinger, Eric L Simpson, Melinda Gooderham, Alan D Irvine

Dermatol Ther (Heidelb)· August 2025

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Statement from the frontal fibrosing alopecia international expert alliance: SOFFIA 2024.
Nekma Meah, Jane Li, Dmitri Wall, Katherine York, Bevin Bhoyrul, Alan D Irvine

J Eur Acad Dermatol Venereol· July 2025

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Telangiectasia in the Distribution of the Superior Vena Cava: A Novel Dermatological Manifestation of 22q11.2 Deletion Syndrome.
Aoife Hollywood, Olga Tummon, Maeve A McAleer, Suzanne Kelleher, Alan D Irvine

Pediatr Dermatol· June 2025

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A pan-European register-based observational study of abrocitinib and conventional systemic therapies in moderate and severe atopic dermatitis: the DREAM TO TREAT AD study protocol.
Elizaveta Gribaleva, Niels Steen Krogh, David Prieto-Merino, Bolaji Coker, Abaigeal Jackson, Alan D Irvine

Skin Health Dis· June 2025

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