Publications by authors named "Alan Deng"

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Modularized Genes in an Adrenal Pathway Reveal a Novel Mechanism in Hypertension Pathogenesis.
David W Deng, Annie Ménard, Alan Y Deng

Int J Mol Sci· April 2025

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Shifting Paradigm from Gene Expressions to Pathways Reveals Physiological Mechanisms in Blood Pressure Control in Causation.
Alan Y Deng, Annie Menard, David W Deng

Int J Mol Sci· January 2023

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Genetics of Normotension Preventing Hypertension Leads to a Novel Physiological Paradigm.
Alan Y Deng

Rev Cardiovasc Med· April 2022

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Conserved mammalian modularity of quantitative trait loci revealed human functional orthologs in blood pressure control.
Alan Y Deng, Annie Ménard

PLoS One· September 2020

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Modularity/non-cumulativity of quantitative trait loci on blood pressure.
Alan Y Deng

J Hum Hypertens· June 2020

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Functional Captures of Multiple Human Quantitative Trait Loci Regulating Blood Pressure with the Use of Orthologs in Genetically Defined Rat Models.
Alan Y Deng, Annie Ménard

Can J Cardiol· May 2020

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Biological convergence of three human and animal model quantitative trait loci for blood pressure.
Alan Y Deng, Annie Ménard

J Hypertens· February 2020

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Functional Dosage of Muscarinic Cholinergic Receptor 3 Signalling, Not the Gene Dose, Determines Its Hypertension Pathogenesis.
Alan Y Deng, Julie-Émilie Huot-Marchard, Denis deBlois, Eric Thorin, Cristina Chauvet

Can J Cardiol· May 2019

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Novel Pathogenesis of Hypertension and Diastolic Dysfunction Caused by M3R (Muscarinic Cholinergic 3 Receptor) Signaling.
Alan Y Deng, Denis deBlois, Stéphane A Laporte, Danielle Gelinas, Jean-Claude Tardif

Hypertension· September 2018

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Structural Insight into the Photochemistry of Split Green Fluorescent Proteins: A Unique Role for a His-Tag.
Alan Deng, Steven G Boxer

J Am Chem Soc· January 2018

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Retinoblastoma-associated protein 140 as a candidate for a novel etiological gene to hypertension.
Kimberley Crespo, Annie Ménard, Alan Y Deng

Clin Exp Hypertens· December 2016

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Alterations in Fibronectin Type III Domain Containing 1 Protein Gene Are Associated with Hypertension.
Alan Y Deng, Cristina Chauvet, Annie Ménard

PLoS One· August 2016

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Two candidate genes for two quantitative trait loci epistatically attenuate hypertension in a novel pathway.
Cristina Chauvet, Annie Ménard, Alan Y Deng

J Hypertens· September 2015

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Hypertension Suppression, Not a Cumulative Thrust of Quantitative Trait Loci, Predisposes Blood Pressure Homeostasis to Normotension.
Kimberley Crespo, Annie Ménard, Alan Y Deng

Circ Cardiovasc Genet· August 2015

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Genetic mechanisms of polygenic hypertension: fundamental insights from experimental models.
Alan Y Deng

J Hypertens· April 2015

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Genetics of systolic and diastolic heart failure.
Alan Y Deng

J Hypertens· January 2015

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Genetics of diastolic heart failure.
Alan Y Deng

J Hypertens· December 2013

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Response to the editorial "do epistatic modules exist in the genetic control of blood pressure in Dahl rats? A critical perspective".
Alan Y Deng

Physiol Genomics· December 2013

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Modularization and epistatic hierarchy determine homeostatic actions of multiple blood pressure quantitative trait loci.
Cristina Chauvet, Kimberley Crespo, Annie Ménard, Julie Roy, Alan Y Deng

Hum Mol Genet· November 2013

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Unique quantitative trait loci in synergy permanently improve diastolic dysfunction.
Cristina Chauvet, Kimberley Crespo, Yanfen Shi, Danielle Gelinas, Francine Duval, Alan Y Deng

Can J Cardiol· October 2013

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Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3.
Hari B Kamadurai, Yu Qiu, Alan Deng, Joseph S Harrison, Chris Macdonald

Elife· August 2013

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Combining distinctive and novel loci doubles BP reduction, reverses diastolic dysfunction and mitigates LV hypertrophy.
Kimberley Crespo, Cristina Chauvet, Annie Ménard, Julie Roy, Yanfen Shi, Alan Y Deng

J Hypertens· May 2013

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Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.
Stephen E Kaiser, Kai Mao, Asad M Taherbhoy, Shanshan Yu, Jennifer L Olszewski, Alan Deng

Nat Struct Mol Biol· December 2012

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Novel genes as primary triggers for polygenic hypertension.
Cristina Chauvet, Annie Ménard, Chunjie Xiao, Benjamin Aguila, Marilyne Blain, Alan Y Deng

J Hypertens· January 2012

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Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway.
Asad M Taherbhoy, Stephen W Tait, Stephen E Kaiser, Allison H Williams, Alan Deng

Mol Cell· November 2011

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