Publications by authors named "Alan E Murphy"

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Enzyme Activity-Based Genome-wide Screening for Modifiers of Lysosomal Glucocerebrosidase Uncovers Candidate Risk Factors for Parkinson's Disease.
Vinod Udayar, Pierre-André Gilormini, Julien Bryois, Alexandra Gehrlein, Xi Chen, Alan E Murphy

ACS Cent Sci· October 2025

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Genome-wide insights into generalised anxiety using a dimensional symptom severity approach.
Megan Skelton, Brittany L Mitchell, Elham Assary, Danyang Li, Genevieve Morneau-Vaillancourt, Alan E Murphy

medRxiv· July 2025

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Predicting gene expression from histone marks using chromatin deep learning models depends on histone mark function, regulatory distance and cellular states.
Alan E Murphy, Aydan Askarova, Boris Lenhard, Nathan G Skene, Sarah J Marzi

Nucleic Acids Res· February 2025

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Predicting cell type-specific epigenomic profiles accounting for distal genetic effects.
Alan E Murphy, William Beardall, Marek Rei, Mike Phuycharoen, Nathan G Skene

Nat Commun· November 2024

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rworkflows: automating reproducible practices for the R community.
Brian M Schilder, Alan E Murphy, Nathan G Skene

Nat Commun· January 2024

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Avoiding false discoveries in single-cell RNA-seq by revisiting the first Alzheimer's disease dataset.
Alan E Murphy, Nurun Fancy, Nathan Skene

Elife· December 2023

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EpiCompare: R package for the comparison and quality control of epigenomic peak files.
Sera Choi, Brian M Schilder, Leyla Abbasova, Alan E Murphy, Nathan G Skene

Bioinform Adv· April 2023

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Transcriptomic analyses reveal neuronal specificity of Leigh syndrome associated genes.
Azizia Wahedi, Chandika Soondram, Alan E Murphy, Nathan Skene, Shamima Rahman

J Inherit Metab Dis· March 2023

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A balanced measure shows superior performance of pseudobulk methods in single-cell RNA-sequencing analysis.
Alan E Murphy, Nathan G Skene

Nat Commun· December 2022

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Multidimensional Dynamics of the Proteome in the Neurodegenerative and Aging Mammalian Brain.
Byron Andrews, Alan E Murphy, Michele Stofella, Sarah Maslen, Leonardo Almeida-Souza

Mol Cell Proteomics· February 2022

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MungeSumstats: a Bioconductor package for the standardization and quality control of many GWAS summary statistics.
Alan E Murphy, Brian M Schilder, Nathan G Skene

Bioinformatics· December 2021

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