Publications by authors named "Alan Futran"

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Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using an Enabled Drug Discovery Platform.
Hideyuki Igawa, Zef A Konst, Eric Therrien, Mee Shelley, Heidi Koldsø, Alan S Futran

J Med Chem· December 2024

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Ubiquitin-specific protease 7 inhibitors reveal a differentiated mechanism of p53-driven anti-cancer activity.
Alan S Futran, Tao Lu, Katherine Amberg-Johnson, Jiayi Xu, Xiaoxiao Yang

iScience· May 2024

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Discovery of Non-Nucleotide Small-Molecule STING Agonists Chemotype Hybridization.
Emily C Cherney, Liping Zhang, Julian Lo, Tram Huynh, Donna Wei, Alan Futran

J Med Chem· February 2022

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Leveraging Automation toward Development of a High-Throughput Gene Expression Profiling Platform.
Jing Chen, Alan Futran, Austin Crithary, Sha Li, Alex Wolicki

SLAS Discov· March 2021

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Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1.
Andrew P Degnan, Godwin K Kumi, Christopher W Allard, Erika V Araujo, Walter L Johnson, Alan Futran

ACS Med Chem Lett· March 2021

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Divergent effects of intrinsically active MEK variants on developmental Ras signaling.
Yogesh Goyal, Granton A Jindal, José L Pelliccia, Kei Yamaya, Eyan Yeung, Alan S Futran

Nat Genet· March 2017

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In vivo severity ranking of Ras pathway mutations associated with developmental disorders.
Granton A Jindal, Yogesh Goyal, Kei Yamaya, Alan S Futran, Iason Kountouridis

Proc Natl Acad Sci U S A· January 2017

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Mapping the binding interface of ERK and transcriptional repressor Capicua using photocrosslinking.
Alan S Futran, Saw Kyin, Stanislav Y Shvartsman, A James Link

Proc Natl Acad Sci U S A· July 2015

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ERK as a model for systems biology of enzyme kinetics in cells.
Alan S Futran, A James Link, Rony Seger, Stanislav Y Shvartsman

Curr Biol· November 2013

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Investigations of Pd-catalyzed ArX coupling reactions informed by reaction progress kinetic analysis.
Jinu S Mathew, Martin Klussmann, Hiroshi Iwamura, Fernando Valera, Alan Futran

J Org Chem· June 2006

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