Publications by authors named "Alan Handyside"

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Combined SNP parental haplotyping and intensity analysis identifies meiotic and mitotic aneuploidies and frequent segmental aneuploidies in preimplantation human embryos.
Alan H Handyside, Louise Newnham, Matthew Newnham, Dominika Henning, Jan Velebny

Sci Rep· October 2025

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Developmental, cytogenetic and epigenetic consequences of removing complex proteins and adding melatonin during in vitro maturation of bovine oocytes.
Desmond A R Tutt, Gizem Guven-Ates, Wing Yee Kwong, Rob Simmons, Fei Sang, Alan H Handyside

Front Endocrinol (Lausanne)· December 2023

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Meiotic and mitotic aneuploidies drive arrest of in vitro fertilized human preimplantation embryos.
Rajiv C McCoy, Michael C Summers, Abeo McCollin, Christian S Ottolini, Kamal Ahuja, Alan H Handyside

Genome Med· October 2023

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Preimplantation Genetic Testing for Aneuploidy (PGT-A) Reveals High Levels of Chromosomal Errors in In Vivo-Derived Pig Embryos, with an Increased Incidence When Produced In Vitro.
Reina Jochems, Carla Canedo-Ribeiro, Giuseppe Silvestri, Martijn F L Derks, Hanne Hamland, Alan H Handyside

Cells· March 2023

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Preimplantation Genetic Testing for Aneuploidy Improves Live Birth Rates with In Vitro Produced Bovine Embryos: A Blind Retrospective Study.
Giuseppe Silvestri, Carla Canedo-Ribeiro, María Serrano-Albal, Remi Labrecque, Patrick Blondin, Alan H Handyside

Cells· September 2021

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Copy number analysis of meiotic and postzygotic mitotic aneuploidies in trophectoderm cells biopsied at the blastocyst stage and arrested embryos.
Alan H Handyside, Abeo McCollin, Michael C Summers, Christian S Ottolini

Prenat Diagn· April 2021

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High implantation and clinical pregnancy rates with single vitrified-warmed blastocyst transfer and optional aneuploidy testing for all patients.
Julija Gorodeckaja, Samantha Neumann, Abeo McCollin, Christian S Ottolini, Jinjun Wang, Alan Handyside

Hum Fertil (Camb)· December 2020

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The dawn of the future: 30 years from the first biopsy of a human embryo. The detailed history of an ongoing revolution.
Danilo Cimadomo, Laura Rienzi, Antonio Capalbo, Carmen Rubio, Federica Innocenti, Alan Handyside

Hum Reprod Update· June 2020

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Abnormal cleavage and developmental arrest of human preimplantation embryos in vitro.
Abeo McCollin, Rebecca L Swann, Michael C Summers, Alan H Handyside, Christian S Ottolini

Eur J Med Genet· February 2020

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Preimplantation genetic testing for aneuploidy versus morphology as selection criteria for single frozen-thawed embryo transfer in good-prognosis patients: a multicenter randomized clinical trial.
Santiago Munné, Brian Kaplan, John L Frattarelli, Tim Child, Gary Nakhuda, Alan H Handyside

Fertil Steril· December 2019

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Karyomapping for simultaneous genomic evaluation and aneuploidy screening of preimplantation bovine embryos: The first live-born calves.
Kara J Turner, Giuseppe Silvestri, David H Black, Gemma Dobson, Charlotte Smith, Alan H Handyside

Theriogenology· February 2019

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Is preimplantation genetic testing for aneuploidy an essential tool for embryo selection or a costly 'add-on' of no clinical benefit?
Zev Rosenwaks, Alan H Handyside

Fertil Steril· August 2018

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The pros and cons of preimplantation genetic testing for aneuploidy: clinical and laboratory perspectives.
Zev Rosenwaks, Alan H Handyside, Francesco Fiorentino, Norbert Gleicher, Richard J Paulson

Fertil Steril· August 2018

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Tripolar chromosome segregation drives the association between maternal genotype at variants spanning PLK4 and aneuploidy in human preimplantation embryos.
Rajiv C McCoy, Louise J Newnham, Christian S Ottolini, Eva R Hoffmann, Katerina Chatzimeletiou, Alan H Handyside

Hum Mol Genet· July 2018

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'Designer babies' almost thirty years on.
Alan H Handyside

Reproduction· July 2018

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Forty years of IVF.
Craig Niederberger, Antonio Pellicer, Jacques Cohen, David K Gardner, Gianpiero D Palermo, Alan H Handyside

Fertil Steril· July 2018

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Tripolar mitosis and partitioning of the genome arrests human preimplantation development in vitro.
Christian S Ottolini, John Kitchen, Leoni Xanthopoulou, Tony Gordon, Michael C Summers, Alan H Handyside

Sci Rep· August 2017

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Noninvasive preimplantation genetic testing: dream or reality?
Alan H Handyside

Fertil Steril· November 2016

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The why, the how and the when of PGS 2.0: current practices and expert opinions of fertility specialists, molecular biologists, and embryologists.
Karen Sermon, Antonio Capalbo, Jacques Cohen, Edith Coonen, Martine De Rycke, Alan Handyside

Mol Hum Reprod· August 2016

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Generation of meiomaps of genome-wide recombination and chromosome segregation in human oocytes.
Christian S Ottolini, Antonio Capalbo, Louise Newnham, Danilo Cimadomo, Senthilkumar A Natesan, Alan H Handyside

Nat Protoc· July 2016

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Artificial oocyte activation with calcium ionophore does not cause a widespread increase in chromosome segregation errors in the second meiotic division of the oocyte.
Antonio Capalbo, Christian S Ottolini, Darren K Griffin, Filippo Maria Ubaldi, Alan H Handyside

Fertil Steril· March 2016

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Karyomapping identifies second polar body DNA persisting to the blastocyst stage: implications for embryo biopsy.
Christian S Ottolini, Shaun Rogers, Karen Sage, Michael C Summers, Antonio Capalbo, Alan H Handyside

Reprod Biomed Online· December 2015

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Live births following karyomapping - a "key" milestone in the development of preimplantation genetic diagnosis.
Alan H Handyside

Reprod Biomed Online· September 2015

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Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates.
Christian S Ottolini, Louise Newnham, Antonio Capalbo, Senthilkumar A Natesan, Hrishikesh A Joshi, Alan H Handyside

Nat Genet· July 2015

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Karyomapping-a comprehensive means of simultaneous monogenic and cytogenetic PGD: comparison with standard approaches in real time for Marfan syndrome.
Alan R Thornhill, Alan H Handyside, Christian Ottolini, Senthil A Natesan, Jon Taylor

J Assist Reprod Genet· March 2015

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