Publications by authors named "Alan J Sinclair"

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Addressing educational needs in older adults with type 1 diabetes.
Giuseppe Maltese, Partha Kar, Geraldine Gallen, Debbie Hicks, Alan J Sinclair

Lancet Diabetes Endocrinol· November 2025

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Hypoglycaemia in Older Adults with Diabetes: Pathophysiology, Prevention, and Personalized Care in an Aging Population.
Virginia Boccardi, Alan J Sinclair

Drugs Aging· October 2025

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Challenges, current innovations, and opportunities for managing type 2 diabetes in frail older adults: a position paper of the European Geriatric Medicine Society (EuGMS)-Special Interest Group in Diabetes.
Virginia Boccardi, Gülistan Bahat, Cafer Balci, Isabelle Bourdel-Marchasson, Antoine Christiaens, Alan J Sinclair

Eur Geriatr Med· August 2025

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Older people with type 1 diabetes mellitus: a call for a new management approach.
Giuseppe Maltese, Alan J Sinclair

Nat Rev Endocrinol· July 2025

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Adherence to Physical Activity and Incident Mobility Disability in Older Adults With Mobility Limitations.
Alejandro Álvarez-Bustos, Helio José Coelho-Junior, Riccardo Calvani, Leocadio Rodriguez-Mañas, Matteo Tosato, Alan J Sinclair

J Cachexia Sarcopenia Muscle· June 2025

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Realigning diabetes regimens in older adults: a 4S Pathway to guide simplification and deprescribing strategies.
Medha Munshi, Anna R Kahkoska, Joshua J Neumiller, Anastasia-Stefania Alexopoulos, Nancy A Allen, Alan J Sinclair

Lancet Diabetes Endocrinol· May 2025

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Association between hypoglycaemic drug de-intensification, mortality and hospital admission in older adults with type 2 diabetes: a cohort study emulating a target trial.
Antoine Christiaens, Alexis Cochard, Florence Tubach, Wade Thompson, Alan J Sinclair

Age Ageing· May 2025

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Long-term frailty and physical performance transitions in older people with type-2 diabetes. The MIDFRAIL randomized clinical study.
Olga Laosa, Eva Topinkova, Isabelle Bourdel-Marchasson, Bruno Vellas, Mikel Izquierdo, Alan J Sinclair

J Nutr Health Aging· April 2025

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The Use of SGLT-2 Inhibitors and GLP-1RA in Frail Older People with Diabetes: A Personalised Approach Is Required.
Alan J Sinclair, Ahmed H Abdelhafiz

Metabolites· January 2025

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Ageing well with diabetes: the role of technology.
Giuseppe Maltese, Sybil A McAuley, Steven Trawley, Alan J Sinclair

Diabetologia· October 2024

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Disability and Quality of Life Measures in older frail and prefrail people with type 2 diabetes. The MIDFRAIL-Study.
Alan J Sinclair, Olga Laosa, Jose Antonio Carnicero, Leocadio Rodriguez-Mañas, Alejandro Álvarez-Bustos

Diabetes Res Clin Pract· August 2024

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Glycaemic outcomes in people living with diabetes under 65 and over 65 years old using an intermittently scanned continuous glucose monitoring system.
Carol Wong, Anne De Bray, Naeem Ul Hassan, Ahmed Almohandes, Kyi Zin Thant, Alan J Sinclair

Ther Adv Endocrinol Metab· August 2024

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Comment on Kutz et al. Comparative Cardiovascular Effectiveness and Safety of SGLT-2 Inhibitors, GLP-1 Receptor Agonists, and DPP-4 Inhibitors According to Frailty in Type 2 Diabetes. Diabetes Care 2023;46:2004-2014.
Giuseppe Maltese, Alan J Sinclair

Diabetes Care· April 2024

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First diabetes survey in Surrey Downs Care Homes, 10 years after the UK National Diabetes Audit: What has changed?
Giuseppe Maltese, Nikolaos Fountoulakis, Sarah Jupp, Susan Cook, Hilary Floyd, Alan J Sinclair

Diabet Med· March 2024

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Response rates and associated factors after a multicomponent intervention in frail older adults with diabetes.
Alejandro Álvarez-Bustos, Olga Laosa, Emanuele Marzetti, Jose Antonio Carnicero, Marta Castro-Rodriguez, Alan J Sinclair

Age Ageing· January 2024

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Impact of deintensifying hypoglycaemic drugs in older adults with type 2 diabetes: protocol for an emulation of a target trial.
Antoine Christiaens, Noémie Simon-Tillaux, Wade Thompson, Alan J Sinclair, Séverine Henrard

BMJ Open· November 2023

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Comment on: Data-driven classification of health status of older adults with diabetes: The diabetes and aging study.
Antoine Christiaens, Alan J Sinclair

J Am Geriatr Soc· September 2023

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Metabolic Characteristics of Frail Older People with Diabetes Mellitus-A Systematic Search for Phenotypes.
Ahmed H Abdelhafiz, Grace L Keegan, Alan J Sinclair

Metabolites· May 2023

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Amino Acid Profiles in Older Adults with Frailty: Secondary Analysis from MetaboFrail and BIOSPHERE Studies.
Riccardo Calvani, Anna Picca, Leocadio Rodriguez-Mañas, Matteo Tosato, Hélio José Coelho-Júnior, Alan J Sinclair

Metabolites· April 2023

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Deprescribing Glucose-Lowering Therapy in Older Adults with Diabetes: A Systematic Review of Recommendations.
Antoine Christiaens, Séverine Henrard, Alan J Sinclair, Florence Tubach, Dominique Bonnet-Zamponi

J Am Med Dir Assoc· March 2023

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Overtreatment of older people with type 2 diabetes-a high impact frequent occurrence in need of a new definition.
Antoine Christiaens, Séverine Henrard, Benoit Boland, Alan J Sinclair

Diabet Med· February 2023

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Metabolic Impact of Frailty Changes Diabetes Trajectory.
Alan J Sinclair, Ahmed H Abdelhafiz

Metabolites· February 2023

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Multimorbidity, Frailty and Diabetes in Older People-Identifying Interrelationships and Outcomes.
Alan J Sinclair, Ahmed H Abdelhafiz

J Pers Med· November 2022

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Hypoglycaemic therapy in frail older people with type 2 diabetes mellitus-a choice determined by metabolic phenotype.
Alan J Sinclair, Daniel Pennells, Ahmed H Abdelhafiz

Aging Clin Exp Res· September 2022

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Unravelling the frailty syndrome in diabetes.
Alan J Sinclair, Ahmed H Abdelhafiz

Lancet Healthy Longev· November 2021

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