Publications by authors named "Alan K Howe"

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The focal adhesion protein talin is a mechanically gated A-kinase anchoring protein.
Mingu Kang, Yasumi Otani, Yanyu Guo, Jie Yan, Benjamin T Goult, Alan K Howe

Proc Natl Acad Sci U S A· March 2024

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Protein kinase A is a functional component of focal adhesions.
Mingu Kang, Amanda J Senatore, Hannah Naughton, Madeline McTigue, Rachel J Beltman, Alan K Howe

J Biol Chem· May 2024

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Protein Kinase A is a Functional Component of Focal Adhesions.
Mingu Kang, Amanda J Senatore, Hannah Naughton, Madeline McTigue, Rachel J Beltman, Alan K Howe

bioRxiv· March 2024

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The focal adhesion protein talin is a mechanically-gated A-kinase anchoring protein (AKAP).
Mingu Kang, Yasumi Otani, Yanyu Guo, Jie Yan, Benjamin T Goult, Alan K Howe

bioRxiv· August 2023

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Protein Kinase A in cellular migration-Niche signaling of a ubiquitous kinase.
Kathryn V Svec, Alan K Howe

Front Mol Biosci· July 2022

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Protein kinase A activity is regulated by actomyosin contractility during cell migration and is required for durotaxis.
Andrew J McKenzie, Kathryn V Svec, Tamara F Williams, Alan K Howe

Mol Biol Cell· January 2020

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Single Cell Durotaxis Assay for Assessing Mechanical Control of Cellular Movement and Related Signaling Events.
Kathryn V Svec, Johnathan B Patterson, Nyla Naim, Alan K Howe

J Vis Exp· August 2019

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The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation.
Andrew J McKenzie, Stephanie R Hicks, Kathryn V Svec, Hannah Naughton, Zöe L Edmunds, Alan K Howe

Sci Rep· May 2018

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AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion.
Brian Cunniff, Andrew J McKenzie, Nicholas H Heintz, Alan K Howe

Mol Biol Cell· September 2016

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Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor.
Adam C Mirando, Pengfei Fang, Tamara F Williams, Linda C Baldor, Alan K Howe

Sci Rep· August 2015

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Anchoring of protein kinase A by ERM (ezrin-radixin-moesin) proteins is required for proper netrin signaling through DCC (deleted in colorectal cancer).
Paula B Deming, Shirley L Campbell, Jamie B Stone, Robert L Rivard, Alison L Mercier, Alan K Howe

J Biol Chem· February 2015

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Cellular control of connective tissue matrix tension.
Helene M Langevin, Maiken Nedergaard, Alan K Howe

J Cell Biochem· August 2013

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Stress and matrix-responsive cytoskeletal remodeling in fibroblasts.
Rosalyn D Abbott, Cathryn Koptiuch, James C Iatridis, Alan K Howe, Gary J Badger

J Cell Physiol· January 2013

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Live free or die: stretch-induced apoptosis occurs when adaptive reorientation of annulus fibrosus cells is restricted.
Rosalyn D Abbott, Alan K Howe, Helene M Langevin, James C Iatridis

Biochem Biophys Res Commun· May 2012

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Protein kinase A activity and anchoring are required for ovarian cancer cell migration and invasion.
Andrew J McKenzie, Shirley L Campbell, Alan K Howe

PLoS One· February 2012

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Direct modulation of the protein kinase A catalytic subunit α by growth factor receptor tyrosine kinases.
George B Caldwell, Alan K Howe, Christian K Nickl, Wolfgang R Dostmann, Bryan A Ballif

J Cell Biochem· January 2012

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Negative regulation of HIF-1α by an FBW7-mediated degradation pathway during hypoxia.
Jessica M Cassavaugh, Sarah A Hale, Theresa L Wellman, Alan K Howe, Cheung Wong

J Cell Biochem· December 2011

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Cross-talk between calcium and protein kinase A in the regulation of cell migration.
Alan K Howe

Curr Opin Cell Biol· October 2011

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Fibroblast cytoskeletal remodeling contributes to connective tissue tension.
Helene M Langevin, Nicole A Bouffard, James R Fox, Bradley M Palmer, Junru Wu, Alan K Howe

J Cell Physiol· May 2011

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Tissue stretch induces nuclear remodeling in connective tissue fibroblasts.
Helene M Langevin, Kirsten N Storch, Robert R Snapp, Nicole A Bouffard, Gary J Badger, Alan K Howe

Histochem Cell Biol· April 2010

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AKAP-independent localization of type-II protein kinase A to dynamic actin microspikes.
Robert L Rivard, Monique Birger, Kara J Gaston, Alan K Howe

Cell Motil Cytoskeleton· September 2009

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Protein kinase A regulates 3-phosphatidylinositide dynamics during platelet-derived growth factor-induced membrane ruffling and chemotaxis.
Paula B Deming, Shirley L Campbell, Linda C Baldor, Alan K Howe

J Biol Chem· December 2008

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Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery.
Timothy J Phalen, Kelly Weirather, Paula B Deming, Vikas Anathy, Alan K Howe

J Cell Biol· December 2006

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Subcutaneous tissue fibroblast cytoskeletal remodeling induced by acupuncture: evidence for a mechanotransduction-based mechanism.
Helene M Langevin, Nicole A Bouffard, Gary J Badger, David L Churchill, Alan K Howe

J Cell Physiol· June 2006

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Spatial regulation of the cAMP-dependent protein kinase during chemotactic cell migration.
Alan K Howe, Linda C Baldor, Brian P Hogan

Proc Natl Acad Sci U S A· October 2005

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