Publications by authors named "Alan Lazarus"

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Antagonism of the Platelet-Activating Factor Pathway Mitigates Inflammatory Adverse Events Driven by Anti-erythrocyte Antibody Therapy in Mice.
Kevin Doyoon Won, Lazaro Gil Gonzalez, Yoelys Cruz-Leal, Alequis Pavon Oro, Alan H Lazarus

J Immunol· May 2024

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Human Fc gamma receptor IIIA blockade inhibits platelet destruction in a humanized murine model of ITP.
Lazaro Gil Gonzalez, Kevin D Won, Zoya Tawhidi, Emma Cummins, Yoelys Cruz-Leal, Alan H Lazarus

Blood Adv· April 2024

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Trogocytosis drives red blood cell antigen loss in association with antibody-mediated immune suppression.
Yoelys Cruz-Leal, Peter A A Norris, Lazaro Gil Gonzalez, Danielle Marjoram, Hanna Wabnitz, Alan H Lazarus

Blood· February 2024

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B cells and antibodies in refractory immune thrombocytopenia.
Anaïs Roeser, Alan H Lazarus, Matthieu Mahévas

Br J Haematol· October 2023

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Serum from half of patients with immune thrombocytopenia trigger macrophage phagocytosis of platelets.
Peter A A Norris, Zoya Tawhidi, Ulrich J Sachs, Christine M Cserti-Gazdewich, Yulia Lin, Alan H Lazarus

Blood Adv· July 2023

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Image-based estimation of the left ventricular cavity volume using deep learning and Gaussian process with cardio-mechanical applications.
Arash Rabbani, Hao Gao, Alan Lazarus, David Dalton, Yuzhang Ge

Comput Med Imaging Graph· June 2023

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TEMRA: the CD8 subset in chronic ITP?
Alan H Lazarus, John W Semple

Blood· May 2023

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Antigen copy number and antibody dose can determine the outcome of erythrocyte alloimmunization inducing either antibody-mediated immune suppression or enhancement in a murine model.
Hanna Wabnitz, Yoelys Cruz-Leal, Alan H Lazarus

Transfusion· April 2023

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Antigen-specific IgG subclass composition in recipient mice can indicate the degree of red blood cell alloimmunization as well as discern between primary and secondary immunization.
Hanna Wabnitz, Yoelys Cruz-Leal, Alan H Lazarus

Transfusion· March 2023

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THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets.
Lazaro Gil Gonzalez, Yuniel Fernandez-Marrero, Peter Alan Albert Norris, Zoya Tawhidi, Yuexin Shan, Alan H Lazarus

PLoS One· December 2022

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Sensitivity analysis and inverse uncertainty quantification for the left ventricular passive mechanics.
Alan Lazarus, David Dalton, Dirk Husmeier, Hao Gao

Biomech Model Mechanobiol· June 2022

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Bayesian optimisation for efficient parameter inference in a cardiac mechanics model of the left ventricle.
Agnieszka Borowska, Hao Gao, Alan Lazarus, Dirk Husmeier

Int J Numer Method Biomed Eng· May 2022

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Neural network-based left ventricle geometry prediction from CMR images with application in biomechanics.
Lukasz Romaszko, Agnieszka Borowska, Alan Lazarus, David Dalton, Colin Berry

Artif Intell Med· September 2021

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Could antigen loss be a potential mechanism to explain antibody-mediated immune suppression?
Yoelys Cruz-Leal, Alan H Lazarus

Transfusion· April 2021

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Anti-inflammatory activity of CD44 antibodies in murine immune thrombocytopenia is mediated by Fcγ receptor inhibition.
Peter A A Norris, Gurleen Kaur, Ramsha Khan, Guangheng Zhu, Heyu Ni, Alan H Lazarus

Blood· April 2021

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FcγRI and FcγRIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/IIIa autoantibody-opsonized platelets in immune thrombocytopenia.
Peter A A Norris, George B Segel, W Richard Burack, Ulrich J Sachs, Suzanne N Lissenberg-Thunnissen, Alan H Lazarus

Haematologica· January 2021

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New insights into IVIg mechanisms and alternatives in autoimmune and inflammatory diseases.
Peter A A Norris, Gurleen Kaur, Alan H Lazarus

Curr Opin Hematol· November 2020

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Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP.
Ramsha Khan, Melissa Menard, Chao-Ching Jen, Xi Chen, Peter A A Norris, Alan H Lazarus

Blood· June 2020

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Analysis of Cardiac Amyloidosis Progression Using Model-Based Markers.
Wenguang Li, Alan Lazarus, Hao Gao, Ana Martinez-Naharro, Marianna Fontana

Front Physiol· April 2020

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The use of IVIg in fetal and neonatal alloimmune thrombocytopenia- Principles and mechanisms.
Hanna Wabnitz, Ramsha Khan, Alan H Lazarus

Transfus Apher Sci· February 2020

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Fast parameter inference in a biomechanical model of the left ventricle by using statistical emulation.
Vinny Davies, Umberto Noè, Alan Lazarus, Hao Gao, Benn Macdonald

J R Stat Soc Ser C Appl Stat· November 2019

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Treating murine inflammatory diseases with an anti-erythrocyte antibody.
Andrew R Crow, Rick Kapur, Sandra Koernig, Ian K Campbell, Chao-Ching Jen, Alan H Lazarus

Sci Transl Med· August 2019

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Gaussian process emulation to accelerate parameter estimation in a mechanical model of the left ventricle: a critical step towards clinical end-user relevance.
Umberto Noè, Alan Lazarus, Hao Gao, Vinny Davies, Benn Macdonald

J R Soc Interface· July 2019

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Glycoprotein V is a relevant immune target in patients with immune thrombocytopenia.
Richard Vollenberg, Rabie Jouni, Peter A A Norris, Monika Burg-Roderfeld, Nina Cooper, Alan H Lazarus

Haematologica· June 2019

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Complications of a severe autoimmune hemolytic anemia crisis: transfusional iron overload and gangrenous cholecystitis.
Isabella Menchetti, Yulia Lin, Christine Cserti-Gazdewich, Jenette Goldstein, Calvin Law, Alan Lazarus

Transfusion· December 2018

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