Publications by authors named "Alan P Fields"

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Protein kinase Cι dictates tumor trajectory, cell plasticity, and immune surveillance in lung adenocarcinoma.
Duy T Nguyen, Luis I Prieto, Cheng Zhang, Hu Li, Andras Khoor, Alan P Fields

Cell Rep· November 2025

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A Phase 2 Trial of Protein Kinase C Iota Inhibition With the Combination of Auranofin and Sirolimus in Patients With Recurrent Ovarian Cancer.
Aminah Jatoi, Nathan R Foster, Andrea Wahner Hendrickson, Matthew S Block, S John Weroha, Alan P Fields

Am J Clin Oncol· October 2025

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Endoxifen downregulates AKT phosphorylation through protein kinase C beta 1 inhibition in ERα+ breast cancer.
Swaathi Jayaraman, Xinyan Wu, Krishna R Kalari, Xiaojia Tang, Mary J Kuffel, Alan P Fields

NPJ Breast Cancer· December 2023

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Protein kinase Cι mediates immunosuppression in lung adenocarcinoma.
Ning Yin, Yi Liu, Capella Weems, Barath Shreeder, Yanyan Lou, Alan P Fields

Sci Transl Med· November 2022

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Regulates Autophagy and Pancreatic Tumorigenesis in Mice.
Kristin S Inman, Yi Liu, Michele L Scotti Buzhardt, Michael Leitges, Murli Krishna, Alan P Fields

Cancers (Basel)· February 2022

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Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth.
Danielle R Cook, Melissa Kang, Timothy D Martin, Joseph A Galanko, Gabriela H Loeza, Alan P Fields

Cancer Res· January 2022

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Protein kinase C and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities.
Rajappa S Kenchappa, Yi Liu, Michael G Argenziano, Matei A Banu, Ann C Mladek, Alan P Fields

Cell Rep· November 2021

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Editorial.
Alan P Fields

Adv Biol Regul· May 2021

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Recurrent copy number gains drive PKCι expression and PKCι-dependent oncogenic signaling in human cancers.
Yi Liu, Verline Justilien, Alan P Fields, Nicole R Murray

Adv Biol Regul· December 2020

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FoxM1 insufficiency hyperactivates Ect2-RhoA-mDia1 signaling to drive cancer.
Jazeel F Limzerwala, Karthik B Jeganathan, Jake A Kloeber, Brian A Davies, Cheng Zhang, Alan P Fields

Nat Cancer· October 2020

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Protein kinase Cι promotes UBF1-ECT2 binding on ribosomal DNA to drive rRNA synthesis and transformed growth of non-small-cell lung cancer cells.
Verline Justilien, Kayla C Lewis, Kayleah M Meneses, Lee Jamieson, Nicole R Murray, Alan P Fields

J Biol Chem· June 2020

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Oncogenic protein kinase Cι signaling mechanisms in lung cancer: Implications for improved therapeutic strategies.
Ning Yin, Yi Liu, Nicole R Murray, Alan P Fields

Adv Biol Regul· January 2020

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Chromosome 3q26 Gain Is an Early Event Driving Coordinated Overexpression of the PRKCI, SOX2, and ECT2 Oncogenes in Lung Squamous Cell Carcinoma.
Yi Liu, Ning Yin, Xue Wang, Andras Khoor, Vaishnavi Sambandam, Zoe A Fields, Alan P Fields

Cell Rep· January 2020

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Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma.
Ning Yin, Yi Liu, Andras Khoor, Xue Wang, E Aubrey Thompson, Alan P Fields

Cancer Cell· December 2019

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Oncogenic Ect2 signaling regulates rRNA synthesis in NSCLC.
Verline Justilien, Kayla C Lewis, Nicole R Murray, Alan P Fields

Small GTPases· September 2019

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Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma.
Ning Yin, Yi Liu, Andras Khoor, Xue Wang, E Aubrey Thompson, Alan P Fields

Cancer Cell· August 2019

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Protein kinase C: A versatile oncogene in the lung.
Alan P Fields, Syed A Ali, Verline Justilien, Nicole R Murray

Mol Cell Oncol· May 2018

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A proof-of-concept trial of protein kinase C iota inhibition with auranofin for the paclitaxel-induced acute pain syndrome.
Aminah Jatoi, Megan E Grudem, Travis J Dockter, Matthew S Block, Jose C Villasboas, Alan P Fields

Support Care Cancer· March 2017

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Ect2-Dependent rRNA Synthesis Is Required for KRAS-TRP53-Driven Lung Adenocarcinoma.
Verline Justilien, Syed A Ali, Lee Jamieson, Ning Yin, Adrienne D Cox, Alan P Fields

Cancer Cell· February 2017

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Targeting oncogenic protein kinase Cι for treatment of mutant KRAS LADC.
Alan P Fields, Syed A Ali, Verline Justilien, Nicole R Murray

Small GTPases· January 2017

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SOX2 Determines Lineage Restriction: Modeling Lung Squamous Cell Carcinoma in the Mouse.
Nicole R Murray, Verline Justilien, Alan P Fields

Cancer Cell· October 2016

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Oncogenic PKCι decides tumor-initiating cell fate.
Alan P Fields, Syed A Ali, Nicole R Murray

Cell Cycle· September 2016

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Stabilin-1 is expressed in human breast cancer and supports tumor growth in mammary adenocarcinoma mouse model.
Vladimir Riabov, Shuiping Yin, Bin Song, Aida Avdic, Kai Schledzewski, Alan P Fields

Oncotarget· May 2016

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Protein Kinase Cι Drives a NOTCH3-dependent Stem-like Phenotype in Mutant KRAS Lung Adenocarcinoma.
Syed A Ali, Verline Justilien, Lee Jamieson, Nicole R Murray, Alan P Fields

Cancer Cell· March 2016

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The chromosome 3q26 OncCassette: A multigenic driver of human cancer.
Alan P Fields, Verline Justilien, Nicole R Murray

Adv Biol Regul· January 2016

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