Publications by authors named "Alan Sanders"

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Expanding the genetic landscape of endometriosis: Integrative -omics analyses implicate key genes and pathways in a multi-ancestry study of over one million women.
Shefali Verma, Lindsay Guare, Jagyashila Das, Lannawill Caruth, Ananya Rajagopalan, Alan Sanders

Res Sq· December 2025

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Hypervirulent Klebsiella pneumoniae causing aortitis retains its capsule and mucoviscosity and remains genotypically and phenotypically stable over time.
Thomas A Russo, Ulrike Carlino-MacDonald, Zachary J Drayer, Connor J Davies, Alan Hutson, Alan Sanders

Sci Rep· November 2025

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PICALM Alzheimer's risk allele causes aberrant lipid droplets in microglia.
Alena Kozlova, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Stanislau Smirnou, Alan R Sanders

Nature· October 2025

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Case 17-2025: A Man with Respiratory Failure and Shock after Kidney Transplantation. Reply.
Camille N Kotton, Kassem Safa, Alan M Sanders

N Engl J Med· October 2025

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Superior performance of two combined polygenic scores for predicting skin cancer risk and differentiating risk of melanoma from keratinocyte carcinomas in two cohorts.
Luzheng Liu, Huy Tran, Ashley J Mulford, Zhuqing Shi, Jun Wei, Alan R Sanders

JAAD Int· August 2025

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Hypervirulent Klebsiella pneumoniae causing aortitis retains its capsule and mucoviscosity and remains genotypically and phenotypically stable over time.
Thomas A Russo, Ulrike Carlino-MacDonald, Zachary J Drayer, Connor J Davies, Alan Hutson, Alan Sanders

Res Sq· August 2025

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Polygenic Score Complements Family History and Lynch Syndrome Genes for Predicting Colorectal Cancer Risk.
Talia Y Helfand, Jun Wei, Ashley J Mulford, Huy Tran, Zhuqing Shi, Alan R Sanders

JCO Precis Oncol· July 2025

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Psychiatric disorders converge on common pathways but diverge in cellular context, spatial distribution, and directionality of genetic effects.
Worrawat Engchuan, Omar Shanta, Kuldeep Kumar, Jeffrey R MacDonald, Bhooma Thiruvahindrapuram, Alan R Sanders

medRxiv· July 2025

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A cross-disorder analysis of CNVs finds novel loci and dose-dependent relationships of genes to psychiatric traits.
Omar Shanta, Marieke Klein, Molly Sacks, Jeffrey R MacDonald, Adam Maihofer, Alan R Sanders

medRxiv· July 2025

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Estimating Cancer Penetrance in Carriers of BRCA2 Pathogenic Variants Using Cancer-Specific Polygenic Scores.
Brendan Prassas, Zhuqing Shi, Huy Tran, Jun Wei, Chi-Hsiung Wang, Alan R Sanders

Cancer Med· June 2025

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Case 17-2025: A 61-Year-Old Man with Respiratory Failure and Shock after Kidney Transplantation.
Camille N Kotton, Rory L Cochran, Alan M Sanders, Kassem Safa, Maxwell T Roth

N Engl J Med· June 2025

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Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication.
Xiaojie Zhao, Yan Li, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Alan R Sanders

Mol Neurodegener· May 2025

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Global multi-ancestry genetic study elucidates genes and biological pathways associated with thyroid cancer and benign thyroid diseases.
Samantha L White, Maizy S Brasher, Jack Pattee, Wei Zhou, Sinéad Chapman, Alan R Sanders

medRxiv· May 2025

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Development and validation of a genetic probability for venous thromboembolism.
Zhuqing Shi, Ashley J Mulford, Huy Tran, Michal Filipczak, Song Gao, Alan R Sanders

Res Pract Thromb Haemost· May 2025

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Single-cell multiomics of neuronal activation reveals context-dependent genetic control of brain disorders.
Lifan Liang, Siwei Zhang, Zicheng Wang, Hanwen Zhang, Chuxuan Li, Alan R Sanders

bioRxiv· February 2025

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Validation of GenProb-T1D and its clinical utility for differentiating types of diabetes in a biobank from a US healthcare system.
Liana K Billings, Zhuqing Shi, Ashley J Mulford, Jun Wei, Huy Tran, Alan R Sanders

J Diabetes Investig· January 2025

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Lipid trajectories improve risk models for Alzheimer's disease and mild cognitive impairment.
Bruce A Chase, Roberta Frigerio, Chad J Yucus, Smita Patel, Demetrius Maraganore, Alan R Sanders

J Lipid Res· January 2025

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Migraine Genetic Susceptibility Does Not Strongly Influence Migraine Characteristics and Outcomes in a Treated, Real-World, Community Cohort.
Bruce A Chase, Roberta Frigerio, Susan Rubin, Irene Semenov, Steven Meyers, Alan R Sanders

J Clin Med· January 2025

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Expanding the genetic landscape of endometriosis: Integrative -omics analyses uncover key pathways from a multi-ancestry study of over 900,000 women.
Lindsay A Guare, Jagyashila Das, Lannawill Caruth, Ananya Rajagopalan, Alexis T Akerele, Alan R Sanders

medRxiv· November 2024

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Scaled and efficient derivation of loss-of-function alleles in risk genes for neurodevelopmental and psychiatric disorders in human iPSCs.
Hanwen Zhang, Ada McCarroll, Lilia Peyton, Sol Díaz de León-Guerrerro, Siwei Zhang, Alan R Sanders

Stem Cell Reports· October 2024

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An Integrative Migraine Polygenic Risk Score Is Associated with Age at Onset But Not Chronification.
Bruce A Chase, Roberta Frigerio, Susan Rubin, Tiffani Franada, Irene Semenov, Alan R Sanders

J Clin Med· October 2024

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Lipid Trajectories Improve Risk Models for Alzheimer's Disease and Mild Cognitive Impairment.
Bruce A Chase, Roberta Frigerio, Chad J Yucus, Smita Patel, Demetrius Maraganore, Alan R Sanders

medRxiv· September 2024

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Alzheimer's disease protective allele of modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication.
Xiaojie Zhao, Yan Li, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Alan R Sanders

medRxiv· August 2024

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Alzheimer's disease risk allele of causes detrimental lipid droplets in microglia.
Alena Kozlova, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Stanislau Smirnou, Alan R Sanders

Res Sq· May 2024

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Scaled and Efficient Derivation of Loss of Function Alleles in Risk Genes for Neurodevelopmental and Psychiatric Disorders in Human iPSC.
Hanwen Zhang, Lilia Peyton, Ada McCarroll, Sol Díaz de León Guerrerro, Siwei Zhang, Alan R Sanders

bioRxiv· March 2024

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