Publications by authors named "Alastair D Lamb"

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Cost Effectiveness of Local Anaesthetic Transperineal Versus Transrectal Biopsy: Results from the TRANSLATE Study.
Matthew Little, Jane Wolstenholme, Filipa Landeiro, Ioana R Marian, Roxanne Williams, Alastair D Lamb

Eur Urol Focus· December 2025

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Single-cell analysis uncovers preserved prostate cancer lineages and universally altered pathways in Matrigel-free patient-derived organoids.
Robin Dolgos, Romuald Parmentier, Jing Wang, Raphaëlle Servant, Arnoud J Templeton, Alastair D Lamb

Cell Rep· October 2025

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Screening for prostate cancer.
Pinky Kotecha, Prabhakar Rajan, Sandy Figiel, Alastair D Lamb

BMJ· May 2025

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Protocol for a randomised phase 3 trial evaluating the role of Finasteride in Active Surveillance for men with low and intermediate-risk prostate cancer: the FINESSE Study.
Marcus Cumberbatch, Bernard North, Roseann Kealy, Samuel Smith, Rachel Hubbard, Alastair D Lamb

BMJ Open· February 2025

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Clinical Implications of Basic Research: Exploring the Transformative Potential of Spatial 'Omics in Uro-oncology.
Sandy Figiel, Anthony Bates, David A Braun, Renu Eapen, Markus Eckstein, Alastair D Lamb

Eur Urol· January 2025

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Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of epithelial cancers.
Andrew Erickson, Sandy Figiel, Timothy Rajakumar, Srinivasa Rao, Wencheng Yin, Alastair D Lamb

PLoS One· January 2025

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Evidence for local anaesthetic transperineal biopsy versus transrectal prostate biopsy.
Alastair D Lamb, Filipa Landeiro, Ioana R Marian, Steve Tuck, Richard J Bryant

BMJ· December 2024

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Prostate cancer detection after atypical small acinar proliferation (ASAP): A 10-year single-centre cohort.
Thineskrishna Anbarasan, Mutie Raslan, Kanchan Ghosh, Philip Macklin, Claudia Mercader, Alastair D Lamb

BJUI Compass· September 2024

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Perspectives on technology - prostate cancer: is local anaesthetic transperineal prostate biopsy really better than transrectal biopsy?
Christopher Berridge, Altan Omer, Francisco Lopez, Richard J Bryant, Alastair D Lamb

BJU Int· August 2024

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First-in-man study of the PSMA Minibody IR800-IAB2M for molecularly targeted intraoperative fluorescence guidance during radical prostatectomy.
Freddie C Hamdy, Alastair D Lamb, Iain D C Tullis, Clare Verrill, Ines Rombach, Adam Lambert

Eur J Nucl Med Mol Imaging· August 2024

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Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics.
Trishna A Desai, Åsa K Hedman, Marios Dimitriou, Mine Koprulu, Sandy Figiel, Alastair D Lamb

EBioMedicine· July 2024

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Statistical analysis plan for the TRANSLATE (TRANSrectal biopsy versus Local Anaesthetic Transperineal biopsy Evaluation of potentially clinically significant prostate cancer) multicentre randomised controlled trial.
Ioana R Marian, Alexander Ooms, Jane Holmes, Matthew J Parkes, Alastair D Lamb

Trials· June 2024

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Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features.
Srinivasa Rao, Clare Verrill, Lucia Cerundolo, Nasullah Khalid Alham, Zeynep Kaya, Adam Lambert, Alastair D Lamb

Genome Med· February 2024

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Aligning germline and somatic mutations in prostate cancer. Are genetics changing practice?
Olivier Cussenot, Geraldine Cancel-Tassin, Srinivasa R Rao, Dan J Woodcock, Alastair D Lamb

BJU Int· November 2023

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Spatial transcriptomic analysis of virtual prostate biopsy reveals confounding effect of tissue heterogeneity on genomic signatures.
Sandy Figiel, Wencheng Yin, Dimitrios Doultsinos, Andrew Erickson, Ninu Poulose, Alastair D Lamb

Mol Cancer· October 2023

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Identifying proteomic risk factors for overall, aggressive and early onset prostate cancer using Mendelian randomization and tumor spatial transcriptomics.
Trishna A Desai, Åsa K Hedman, Marios Dimitriou, Mine Koprulu, Sandy Figiel, Alastair D Lamb

medRxiv· September 2023

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Re: Fifteen-year Outcomes After Monitoring, Surgery, or Radiotherapy for Prostate Cancer.
Abhishek D Sharma, Jose F Lopez, Aaron Leiblich, Tom A Leslie, Alastair D Lamb

Eur Urol· August 2023

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Genomic Evolution and Transcriptional Changes in the Evolution of Prostate Cancer into Neuroendocrine and Ductal Carcinoma Types.
Srinivasa R Rao, Andrew Protheroe, Lucia Cerundolo, David Maldonado-Perez, Lisa Browning, Alastair D Lamb

Int J Mol Sci· August 2023

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Protocol for the TRANSLATE prospective, multicentre, randomised clinical trial of prostate biopsy technique.
Richard J Bryant, Hide Yamamoto, Ben Eddy, Sashi Kommu, Krishna Narahari, Alastair D Lamb

BJU Int· June 2023

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Comparison of traditional outcome measures and self-assessed goal achievement in patients treated surgically for benign prostatic hyperplasia.
Manolis Pratsinis, Gautier Müllhaupt, Sabine Güsewell, Patrick Betschart, Valentin Zumstein, Alastair D Lamb

World J Urol· April 2023

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Spatio-temporal analysis of prostate tumors in situ suggests pre-existence of treatment-resistant clones.
Maja Marklund, Niklas Schultz, Stefanie Friedrich, Emelie Berglund, Firas Tarish, Alastair D Lamb

Nat Commun· September 2022

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Spatially resolved clonal copy number alterations in benign and malignant tissue.
Andrew Erickson, Mengxiao He, Emelie Berglund, Maja Marklund, Reza Mirzazadeh, Alastair D Lamb

Nature· August 2022

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Re: Prostate Cancer Screening Using a Combination of Risk-prediction, MRI, and Targeted Prostate Biopsies (STHLM3-MRI): A Prospective, Population-based, Randomised, Open-label, Non-inferiority Trial.
Mutie Raslan, Claudia Mercader, Alastair D Lamb

Eur Urol· May 2022

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The Use of Digital Pathology and Artificial Intelligence in Histopathological Diagnostic Assessment of Prostate Cancer: A Survey of Prostate Cancer UK Supporters.
Kai Rakovic, Richard Colling, Lisa Browning, Monica Dolton, Margaret R Horton, Alastair D Lamb

Diagnostics (Basel)· May 2022

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