Publications by authors named "Albert S Edge"

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Pharmacological regeneration of sensory hair cells restores afferent innervation and vestibular function.
Hanae Lahlou, Hong Zhu, Wu Zhou, Albert Sb Edge

J Clin Invest· September 2024

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Large-scale annotated dataset for cochlear hair cell detection and classification.
Christopher J Buswinka, David B Rosenberg, Rubina G Simikyan, Richard T Osgood, Katharine Fernandez, Albert Sb Edge

bioRxiv· September 2023

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A Novel Small Molecule Neurotrophin-3 Analogue Promotes Inner Ear Neurite Outgrowth and Synaptogenesis .
Judith S Kempfle, Marlon V Duro, Andrea Zhang, Carolina D Amador, Richard Kuang, Albert S Edge

Front Cell Neurosci· July 2021

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Trk agonist drugs rescue noise-induced hidden hearing loss.
Katharine A Fernandez, Takahisa Watabe, Mingjie Tong, Xiankai Meng, Kohsuke Tani, Albert Sb Edge

JCI Insight· February 2021

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Bisphosphonate-Linked TrkB Agonist: Cochlea-Targeted Delivery of a Neurotrophic Agent as a Strategy for the Treatment of Hearing Loss.
Judith S Kempfle, Kim Nguyen, Christine Hamadani, Nicholas Koen, Albert S Edge

Bioconjug Chem· April 2018

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Distinct capacity for differentiation to inner ear cell types by progenitor cells of the cochlea and vestibular organs.
Will J McLean, Dalton T McLean, Ruth Anne Eatock, Albert S B Edge

Development· December 2016

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Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.
Yen-Fu Cheng, Mingjie Tong, Albert S B Edge

J Biol Chem· September 2016

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Diphtheria Toxin-Induced Cell Death Triggers Wnt-Dependent Hair Cell Regeneration in Neonatal Mice.
Lingxiang Hu, Jingrong Lu, Hao Chiang, Hao Wu, Albert S B Edge

J Neurosci· September 2016

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Comprehensive Expression of Wnt Signaling Pathway Genes during Development and Maturation of the Mouse Cochlea.
Ruishuang Geng, Teppei Noda, Joanna F Mulvaney, Vincent Y W Lin, Albert S B Edge

PLoS One· July 2016

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Sox2 in the differentiation of cochlear progenitor cells.
Judith S Kempfle, Jack L Turban, Albert S B Edge

Sci Rep· March 2016

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Central Gain Restores Auditory Processing following Near-Complete Cochlear Denervation.
Anna R Chambers, Jennifer Resnik, Yasheng Yuan, Jonathon P Whitton, Albert S Edge

Neuron· February 2016

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Manipulating cell fate in the cochlea: a feasible therapy for hearing loss.
Masato Fujioka, Hideyuki Okano, Albert S B Edge

Trends Neurosci· March 2015

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Spiral ganglion stem cells can be propagated and differentiated into neurons and glia.
Marc Diensthuber, Veronika Zecha, Jens Wagenblast, Stefan Arnhold, Albert S B Edge

Biores Open Access· June 2014

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β-Catenin is required for hair-cell differentiation in the cochlea.
Fuxin Shi, Lingxiang Hu, Bonnie E Jacques, Joanna F Mulvaney, Alain Dabdoub, Albert S B Edge

J Neurosci· May 2014

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Inhibition of repulsive guidance molecule, RGMa, increases afferent synapse formation with auditory hair cells.
Aurore Brugeaud, Mingjie Tong, Li Luo, Albert S B Edge

Dev Neurobiol· April 2014

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A promoter-level mammalian expression atlas.

Nature· March 2014

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Lgr5-positive supporting cells generate new hair cells in the postnatal cochlea.
Naomi F Bramhall, Fuxin Shi, Katrin Arnold, Konrad Hochedlinger, Albert S B Edge

Stem Cell Reports· March 2014

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An independent construct for conditional expression of atonal homolog-1.
Mark A Parker, Yen-fu Cheng, Hikaru Kinouchi, Rebecca Bieber, Albert S B Edge

Hum Gene Ther Methods· February 2014

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Ouabain-induced cochlear nerve degeneration: synaptic loss and plasticity in a mouse model of auditory neuropathy.
Yasheng Yuan, Fuxin Shi, Yanbo Yin, Mingjie Tong, Hainan Lang, Albert S B Edge

J Assoc Res Otolaryngol· February 2014

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Loss of osteoprotegerin expression in the inner ear causes degeneration of the cochlear nerve and sensorineural hearing loss.
Shyan-Yuan Kao, Judith S Kempfle, Jane B Jensen, Deborah Perez-Fernandez, Andrew C Lysaght, Albert S Edge

Neurobiol Dis· August 2013

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Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors.
Fuxin Shi, Lingxiang Hu, Albert S B Edge

Proc Natl Acad Sci U S A· August 2013

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Regenerated synapses between postnatal hair cells and auditory neurons.
Mingjie Tong, Aurore Brugeaud, Albert S B Edge

J Assoc Res Otolaryngol· June 2013

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An in vitro model of developmental synaptogenesis using cocultures of human neural progenitors and cochlear explants.
Bryony A Nayagam, Albert S Edge, Karina Needham, Tomoko Hyakumura, Jessie Leung

Stem Cells Dev· March 2013

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Prospects for replacement of auditory neurons by stem cells.
Fuxin Shi, Albert S B Edge

Hear Res· March 2013

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