Publications by authors named "Alberto Del Rio"

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Tailoring a novel colorectal cancer stem cell-targeted therapy by inhibiting the SMYD3/c-MYC axis.
Martina Lepore Signorile, Elisabetta Di Nicola, Giovanna Forte, Paola Sanese, Candida Fasano, Valerio Lantone, Alberto Del Rio

Signal Transduct Target Ther· June 2025

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A new database contains 520 studies investigating the carcinogenicity data of 238 pharmaceuticals across 14 ATC classifications.
Panagiotis G Karamertzanis, Martina Evangelisti, Marco Daniele Parenti, Jochen Vom Brocke, Alberto Del Rio

Front Toxicol· September 2024

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Assessment of cognitive games to improve the quality of life of Parkinson's and Alzheimer's patients.
Álvaro Llorente, Alberto Del Rio, Yusuf Can Semerci, Jorge Alfonso Kurano, David Jimenez

Digit Health· May 2024

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The novel SMYD3 inhibitor EM127 impairs DNA repair response to chemotherapy-induced DNA damage and reverses cancer chemoresistance.
Paola Sanese, Katia De Marco, Martina Lepore Signorile, Francesca La Rocca, Giovanna Forte, Valerio Lantone, Alberto Del Rio

J Exp Clin Cancer Res· May 2024

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SMYD3 Modulates AMPK-mTOR Signaling Balance in Cancer Cell Response to DNA Damage.
Martina Lepore Signorile, Paola Sanese, Elisabetta Di Nicola, Candida Fasano, Giovanna Forte, Alberto Del Rio

Cells· November 2023

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SIRT6 pharmacological inhibition delays skin cancer progression in the squamous cell carcinoma.
Elena Abbotto, Caterina Miro, Francesco Piacente, Annalisa Salis, Melania Murolo, Alberto Del Rio

Biomed Pharmacother· October 2023

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SMYD3 Modulates the HGF/MET Signaling Pathway in Gastric Cancer.
Katia De Marco, Martina Lepore Signorile, Elisabetta Di Nicola, Paola Sanese, Candida Fasano, Alberto Del Rio

Cells· October 2023

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A non-clinical and clinical IUCLID database for 530 pharmaceuticals (part I): Methodological aspects of its development.
Martina Evangelisti, Marco Daniele Parenti, Greta Varchi, Jorge Franco, Jochen Vom Brocke, Alberto Del Rio

Regul Toxicol Pharmacol· August 2023

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Personalizing Digital Health: Adapting Health Technology Systems to Meet the Needs of Different Older Populations.
Jennifer Jimenez, Alberto Del Rio, Arianna N Berman, Miriam Grande

Healthcare (Basel)· July 2023

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Discovery of the 4-aminopiperidine-based compound EM127 for the site-specific covalent inhibition of SMYD3.
Marco Daniele Parenti, Marina Naldi, Elisabetta Manoni, Edoardo Fabini, Daniela Cederfelt, Alberto Del Rio

Eur J Med Chem· December 2022

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A Multi-Port Hardware Energy Meter System for Data Centers and Server Farms Monitoring.
Giuseppe Conti, David Jimenez, Alberto Del Rio, Sandra Castano-Solis, Javier Serrano

Sensors (Basel)· December 2022

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Mutational analysis of ribosomal proteins in a cohort of pediatric patients with T-cell acute lymphoblastic leukemia reveals Q123R, a novel mutation in RPL10.
Lorenza Bacci, Valentina Indio, Guglielmo Rambaldelli, Cristina Bugarin, Franco Magliocchetti, Alberto Del Rio

Front Genet· November 2022

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Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery.
Moustafa S Ghanem, Irene Caffa, Alberto Del Rio, Jorge Franco, Marco Daniele Parenti

Pharmaceuticals (Basel)· July 2022

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Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors.
Jorge Franco, Francesco Piacente, Melanie Walter, Simone Fratta, Moustafa Ghanem, Alberto Del Rio

Pharmaceuticals (Basel)· July 2022

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Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase.
Vladimir O Talibov, Edoardo Fabini, Edward A FitzGerald, Daniele Tedesco, Daniela Cederfeldt, Alberto Del Rio

Chembiochem· May 2021

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Targeting SMYD3 to Sensitize Homologous Recombination-Proficient Tumors to PARP-Mediated Synthetic Lethality.
Paola Sanese, Candida Fasano, Giacomo Buscemi, Cinzia Bottino, Silvia Corbetta, Alberto Del Rio

iScience· October 2020

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Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules.
Giovanna Sociali, Nara Liessi, Alessia Grozio, Irene Caffa, Marco Daniele Parenti, Alberto Del Rio

Mol Divers· August 2020

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Indexes of cardiac autonomic profile detected with short term Holter ECG in health care shift workers: a cross sectional study.
Luigi Isaia Lecca, Davide Setzu, Alberto Del Rio, Marcello Campagna, Pierluigi Cocco

Med Lav· December 2019

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Light-Induced Therapies for Prostate Cancer Treatment.
Claudia Ferroni, Alberto Del Rio, Cecilia Martini, Elisabetta Manoni, Greta Varchi

Front Chem· October 2019

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Unveiling the Biochemistry of the Epigenetic Regulator SMYD3.
Edoardo Fabini, Vladimir O Talibov, Filip Mihalic, Marina Naldi, Manuela Bartolini, Alberto Del Rio

Biochemistry· September 2019

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Small-molecule inhibitors of lysine methyltransferases SMYD2 and SMYD3: current trends.
Edoardo Fabini, Elisabetta Manoni, Claudia Ferroni, Alberto Del Rio, Manuela Bartolini

Future Med Chem· April 2019

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Small Molecules Targeting the miRNA-Binding Domain of Argonaute 2: From Computer-Aided Molecular Design to RNA Immunoprecipitation.
Teresa Bellissimo, Silvia Masciarelli, Elena Poser, Ilaria Genovese, Alberto Del Rio

Methods Mol Biol· January 2018

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SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.
Patrizia Damonte, Giovanna Sociali, Marco Daniele Parenti, Debora Soncini, Inga Bauer, Alberto Del Rio

Bioorg Med Chem· October 2017

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Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model.
Giovanna Sociali, Mirko Magnone, Silvia Ravera, Patrizia Damonte, Tiziana Vigliarolo, Valerio G Vellone, Alberto Del Rio

FASEB J· July 2017

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Erratum: A meta-analysis on age-associated changes in blood DNA methylation: results from an original analysis pipeline for Infinium 450k data.
Maria Giulia Bacalini, Alessio Boattini, Davide Gentilini, Enrico Giampieri, Chiara Pirazzini, Alberto Del Rio

Aging (Albany NY)· April 2016

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