Publications by authors named "Alberto Pascual"

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Human iPSC-derived APOE4/4 Alzheimer´s disease astrocytes exhibit a senescent and pro-inflammatory state that compromises neuronal support.
Laura Caceres-Palomo, Elisabeth Sanchez-Mejias, Laura Trujillo-Estrada, Juan Jose Perez-Moreno, Elba Lopez-Oliva, Alberto Pascual

J Neuroinflammation· December 2025

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Epigenetic control of microglial developmental milestones from proliferative progenitors to efficient phagocytes.
Marta Pereira-Iglesias, Duncan Martinson, Carles Falco, Joel Maldonado-Teixido, Marco González-Domínguez, Alberto Pascual

bioRxiv· November 2025

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Neuroinflammation in Alzheimer disease.
Michael T Heneka, Wiesje M van der Flier, Frank Jessen, Jeroen Hoozemanns, Dietmar Rudolf Thal, Alberto Pascual

Nat Rev Immunol· May 2025

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Inactivation of the PHD3-FOXO3 axis blunts the type I interferon response in microglia and ameliorates Alzheimer's disease progression.
Manuel A Sanchez-Garcia, Nieves Lara-Ureña, Rosana March-Diaz, Clara Ortega-de San Luis, Silvia Quiñones-Cañete, Alberto Pascual

Sci Adv· May 2025

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Microglia mitochondrial complex I deficiency during development induces glial dysfunction and early lethality.
Bella Mora-Romero, Nicolas Capelo-Carrasco, Juan J Pérez-Moreno, María I Alvarez-Vergara, Laura Trujillo-Estrada, Alberto Pascual

Nat Metab· August 2024

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Hif1α-dependent mitochondrial acute O sensing and signaling to myocyte Ca channels mediate arterial hypoxic vasodilation.
Alejandro Moreno-Domínguez, Olalla Colinas, Ignacio Arias-Mayenco, José M Cabeza, Juan L López-Ogayar, Alberto Pascual

Nat Commun· August 2024

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Full protection from SARS-CoV-2 brain infection and damage in susceptible transgenic mice conferred by MVA-CoV2-S vaccine candidate.
Javier Villadiego, Juan García-Arriaza, Reposo Ramírez-Lorca, Roberto García-Swinburn, Daniel Cabello-Rivera, Alberto Pascual

Nat Neurosci· February 2023

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Glia fuel neurons with locally synthesized ketone bodies to sustain memory under starvation.
Bryon Silva, Olivier L Mantha, Johann Schor, Alberto Pascual, Pierre-Yves Plaçais

Nat Metab· February 2022

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Non-productive angiogenesis disassembles Aß plaque-associated blood vessels.
Maria I Alvarez-Vergara, Alicia E Rosales-Nieves, Rosana March-Diaz, Guiomar Rodriguez-Perinan, Nieves Lara-Ureña, Alberto Pascual

Nat Commun· May 2021

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Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1.
Rosana March-Diaz, Nieves Lara-Ureña, Carmen Romero-Molina, Antonio Heras-Garvin, Clara Ortega-de San Luis, Alberto Pascual

Nat Aging· April 2021

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Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart.
Diego Barriales, Itziar Martín-Ruiz, Ana Carreras-González, Marta Montesinos-Robledo, Mikel Azkargorta, Miguel A Pascual-Itoiz, Alberto Pascual

PLoS Biol· January 2021

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Differential deletion of GDNF in the auditory system leads to altered sound responsiveness.
Csaba Harasztosi, Steffen Wolter, Katja Gutsche, María Beatriz Durán-Alonso, Iris López-Hernández, Alberto Pascual

J Neurosci Res· September 2020

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[Measurement of the theta / beta ratio with the quantified electroencephalogram in attention-deficit hyperactivity disorders].
Pedro Ortiz, Fernando Mulas, Antonio Sánchez, Rubén Gandía, Mildred T Rojas, Alberto Pascual

Medicina (B Aires)· April 2020

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Glial-derived neurotrophic factor is essential for blood-nerve barrier functional recovery in an experimental murine model of traumatic peripheral neuropathy.
Chaoling Dong, E Scott Helton, Ping Zhou, Xuan Ouyang, Xavier d'Anglemont de Tassigny, Alberto Pascual

Tissue Barriers· December 2018

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Substantia nigra dopaminergic neurons and striatal interneurons are engaged in three parallel but interdependent postnatal neurotrophic circuits.
Clara Ortega-de San Luis, Manuel A Sanchez-Garcia, Jose Luis Nieto-Gonzalez, Pablo García-Junco-Clemente, Adoracion Montero-Sanchez, Alberto Pascual

Aging Cell· October 2018

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Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo.
Alberto Serrano-Pozo, Manuel A Sánchez-García, Antonio Heras-Garvín, Rosana March-Díaz, Victoria Navarro, Alberto Pascual

PLoS One· August 2017

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Simultaneous Detection of Both GDNF and GFRα1 Expression Patterns in the Mouse Central Nervous System.
Clara Ortega-de San Luis, Alberto Pascual

Front Neuroanat· July 2016

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Fundamental physical cellular constraints drive self-organization of tissues.
Daniel Sánchez-Gutiérrez, Melda Tozluoglu, Joseph D Barry, Alberto Pascual, Yanlan Mao

EMBO J· January 2016

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Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling.
M Carmen Fernández-Agüera, Lin Gao, Patricia González-Rodríguez, C Oscar Pintado, Ignacio Arias-Mayenco, Alberto Pascual

Cell Metab· November 2015

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GDNF gene is associated with tourette syndrome in a family study.
Ismael Huertas-Fernández, Pilar Gómez-Garre, Marcos Madruga-Garrido, Inmaculada Bernal-Bernal, Marta Bonilla-Toribio, Alberto Pascual

Mov Disord· July 2015

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Reply to "GDNF is not required for catecholaminergic neuron survival in vivo".
Alberto Pascual, José López-Barneo

Nat Neurosci· March 2015

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GDNF-based therapies, GDNF-producing interneurons, and trophic support of the dopaminergic nigrostriatal pathway. Implications for Parkinson's disease.
Xavier d'Anglemont de Tassigny, Alberto Pascual, José López-Barneo

Front Neuroanat· March 2015

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Topological progression in proliferating epithelia is driven by a unique variation in polygon distribution.
Daniel Sánchez-Gutiérrez, Aurora Sáez, Alberto Pascual, Luis M Escudero

PLoS One· August 2014

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Effect of hypoxia on lung gene expression and proteomic profile: insights into the pulmonary surfactant response.
Bárbara Olmeda, Todd M Umstead, Patricia Silveyra, Alberto Pascual, José López-Barneo

J Proteomics· April 2014

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GDNF is required for neural colonization of the pancreas.
José Luis Muñoz-Bravo, María Hidalgo-Figueroa, Alberto Pascual, José López-Barneo, Alfonso Leal-Cerro

Development· September 2013

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