Publications by authors named "Aleen D Saxton"

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Tri-snRNP activity modulates tauopathy phenotypes.
Katherine R LeBlanc, Randall J Eck, Aleen D Saxton, Pamela J McMillan, Jeanna M Wheeler

NAR Mol Med· July 2025

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Activation of the heat shock response as a therapeutic strategy for tau toxicity.
Taylor R Stanley, Elizabeth M Otero, Amy L Knight, Aleen D Saxton, Xinxing Ding

Dis Model Mech· September 2024

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Endoplasmic reticulum unfolded protein response transcriptional targets of XBP-1s mediate rescue from tauopathy.
Sarah M Waldherr, Marina Han, Aleen D Saxton, Taylor A Vadset, Pamela J McMillan

Commun Biol· July 2024

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Loss of aly/ALYREF suppresses toxicity in both tau and TDP-43 models of neurodegeneration.
Rebecca L Kow, Aristide H Black, Aleen D Saxton, Nicole F Liachko, Brian C Kraemer

Geroscience· April 2022

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Human Ubiquilin 2 and TDP-43 copathology drives neurodegeneration in transgenic Caenorhabditis elegans.
Aleen D Saxton, Brian C Kraemer

G3 (Bethesda)· August 2021

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AlphaScreen Identifies MSUT2 Inhibitors for Tauopathy-Targeting Therapeutic Discovery.
Jeremy D Baker, Rikki L Uhrich, Timothy J Strovas, Aleen D Saxton, Brian C Kraemer

SLAS Discov· March 2021

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Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes.
Rebecca L Kow, Timothy J Strovas, Pamela J McMillan, Ashley M Jacobi, Mark A Behlke, Aleen D Saxton

Neurobiol Dis· January 2021

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Targeting Pathological Tau by Small Molecule Inhibition of the Poly(A):MSUT2 RNA-Protein Interaction.
Jeremy D Baker, Rikki L Uhrich, Timothy J Strovas, Aleen D Saxton, Brian C Kraemer

ACS Chem Neurosci· August 2020

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Redefining transcriptional regulation of the APOE gene and its association with Alzheimer's disease.
Eun-Gyung Lee, Jessica Tulloch, Sunny Chen, Lesley Leong, Aleen D Saxton

PLoS One· April 2020

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Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy.
Nicole F Liachko, Aleen D Saxton, Pamela J McMillan, Timothy J Strovas, C Dirk Keene

PLoS Genet· December 2019

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Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing.
Janis C Weeks, William M Roberts, Caitlyn Leasure, Brian M Suzuki, Kristin J Robinson, Aleen D Saxton

Sci Rep· January 2018

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The phosphatase calcineurin regulates pathological TDP-43 phosphorylation.
Nicole F Liachko, Aleen D Saxton, Pamela J McMillan, Timothy J Strovas, Heather N Currey

Acta Neuropathol· October 2016

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