Publications by authors named "Alejandra Pera"

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Expression of the inhibitory checkpoints LAG-3, TIM-3, and PD-1 in NK cells and T cells in acute myeloid leukemia: preserved expression of LAG-3 is associated with patient survival.
Isabel Valhondo, Alejandra Pera, Fakhri Hassouneh, Nelson López-Sejas, Pablo Álvarez-Heredia

Cancer Immunol Immunother· October 2025

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Phenotypic, proteomic, and functional analyses of cytokine-induced memory-like NK cells show two distinct subsets based on CD16 expression.
Sofía Carreira-Santos, Marina González-Sánchez, Nelson López-Sejas, Fakhri Hassouneh, Lauro González-Fernández, Alejandra Pera

Sci Rep· October 2025

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Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata.
Jesus Gay-Mimbrera, Pedro Jesús Gómez-Arias, Pablo Álvarez-Heredia, Alexander Batista-Duharte, Irene Rivera-Ruiz, Alejandra Pera

Front Immunol· July 2025

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Epitope Variation in Hemagglutinin and Antibody Responses to Successive A/Victoria A(H1N1) Strains in Young and Older Adults Following Seasonal Influenza Vaccination: A Pilot Study.
Mónica Espinar-García, Isabel María Vallejo-Bermúdez, María Ángeles Onieva-García, Irene Reina-Alfonso, Luis Llapa-Chino, Alejandra Pera

Vaccines (Basel)· July 2025

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Divergent Immune Pathways in Coronary Artery Disease and Aortic Stenosis: The Role of Chronic Inflammation and Senescence.
José Joaquín Domínguez-Del-Castillo, Pablo Álvarez-Heredia, Irene Reina-Alfonso, Maria-Isabel Vallejo-Bermúdez, Rosalía López-Romero, Alejandra Pera

Int J Mol Sci· May 2025

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Spanish HCMV Seroprevalence in the 21st Century.
Pablo Álvarez-Heredia, Irene Reina-Alfonso, José Joaquín Domínguez-Del-Castillo, Fakhri Hassouneh, Carmen Gutiérrez-González, Alejandra Pera

Viruses· December 2023

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Clinical significance of glycogen synthase kinase 3 (GSK-3) expression and tumor budding grade in colorectal cancer: Implications for targeted therapy.
Silvia Guil-Luna, Aurora Rivas-Crespo, Carmen Navarrete-Sirvent, Ana Mantrana, Alejandra Pera

Biomed Pharmacother· November 2023

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Enhanced expression of natural cytotoxicity receptors on cytokine-induced memory-like natural killer cells correlates with effector function.
Sofía Carreira-Santos, Nelson López-Sejas, Marina González-Sánchez, Eva Sánchez-Hernández, Alejandra Pera

Front Immunol· November 2023

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Marked skewing of entire T-cell memory compartment occurs only in a minority of CMV-infected individuals and is unrelated to the degree of memory subset skewing among CMV-specific T-cells.
Stephan Fuhrmann, Bernhard Reus, Oliver Frey, Alejandra Pera, Louis J Picker

Front Immunol· November 2023

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Accelerated T-Cell Immunosenescence in Cytomegalovirus-Seropositive Individuals After Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
Pablo Álvarez-Heredia, Irene Reina-Alfonso, Jose Joaquín Domínguez-Del-Castillo, Carmen Gutiérrez-González, Fakhri Hassouneh, Alejandra Pera

J Infect Dis· August 2023

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A Straightforward Cytometry-Based Protocol for the Comprehensive Analysis of the Inflammatory Valve Infiltrate in Aortic Stenosis.
Pablo Álvarez-Heredia, José Joaquín Domínguez-Del-Castillo, Irene Reina-Alfonso, Carmen Gutiérrez-González, Fakhri Hassouneh, Alejandra Pera

Int J Mol Sci· January 2023

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Immune Checkpoint Inhibitors for Vaccine Improvements: Current Status and New Approaches.
Alexander Batista-Duharte, Fakhri Hassouneh, Pablo Alvarez-Heredia, Alejandra Pera, Rafael Solana

Pharmaceutics· August 2022

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In-Depth Profiling of T-Cell Responsiveness to Commonly Recognized CMV Antigens in Older People Reveals Important Sex Differences.
Bernhard Reus, Stefano Caserta, Martin Larsen, George Morrow, Aalia Bano, Alejandra Pera

Front Immunol· December 2021

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Impact of Cytomegalovirus and Age on T-Cell Subsets Defined by CD161, CD300a, and/or CD57 Expression in Healthy Andalusians.
Martina Formentini, Ana Navas, Fakhri Hassouneh, Nelson Lopez-Sejas, Corona Alonso, Alejandra Pera

J Gerontol A Biol Sci Med Sci· October 2021

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Functional Changes of T-Cell Subsets with Age and CMV Infection.
Fakhri Hassouneh, David Goldeck, Alejandra Pera, Diana van Heemst, P Eline Slagboom

Int J Mol Sci· September 2021

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Cytomegalovirus infection is associated with an increase in aortic stiffness in older men which may be mediated in part by CD4 memory T-cells.
Frances Kirkham, Alejandra Pera, Amanda M Simanek, Aalia Bano, George Morrow

Theranostics· July 2021

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Regulatory T cells and vaccine effectiveness in older adults. Challenges and prospects.
Alexander Batista-Duharte, Alejandra Pera, Salvador F Aliño, Rafael Solana

Int Immunopharmacol· July 2021

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Editorial: Immune Responses to Persistent or Recurrent Antigens: Implications for Immunological Memory and Immunotherapy.
Stefano Caserta, Alejandra Pera

Front Immunol· April 2021

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Characterization of the DNAM-1, TIGIT and TACTILE Axis on Circulating NK, NKT-Like and T Cell Subsets in Patients with Acute Myeloid Leukemia.
Isabel Valhondo, Fakhri Hassouneh, Nelson Lopez-Sejas, Alejandra Pera, Beatriz Sanchez-Correa

Cancers (Basel)· August 2020

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CD28 CD4 T-cell expansions in autoimmune disease suggest a link with cytomegalovirus infection.
Aalia Bano, Alejandra Pera, Ahmad Almoukayed, Thomas H S Clarke, Sukaina Kirmani

F1000Res· May 2020

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Current progress in NK cell biology and NK cell-based cancer immunotherapy.
Raquel Tarazona, Nelson Lopez-Sejas, Beatriz Guerrero, Fakhri Hassouneh, Isabel Valhondo, Alejandra Pera

Cancer Immunol Immunother· May 2020

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CD28 pro-atherogenic CD4 T-cells explain the link between CMV infection and an increased risk of cardiovascular death.
Alejandra Pera, Stefano Caserta, Fabio Albanese, Pinar Blowers, George Morrow

Theranostics· September 2019

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DNAM-1 and the TIGIT/PVRIG/TACTILE Axis: Novel Immune Checkpoints for Natural Killer Cell-Based Cancer Immunotherapy.
Beatriz Sanchez-Correa, Isabel Valhondo, Fakhri Hassouneh, Nelson Lopez-Sejas, Alejandra Pera

Cancers (Basel)· June 2019

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Culture with Interleukin-15 Leads to Expression of Activating Receptors and Recovery of Natural Killer Cell Function in Acute Myeloid Leukemia Patients.
Beatriz Sanchez-Correa, Juan M Bergua, Alejandra Pera, Carmen Campos, Maria Jose Arcos

Front Immunol· August 2017

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Effect of Cytomegalovirus (CMV) and Ageing on T-Bet and Eomes Expression on T-Cell Subsets.
Fakhri Hassouneh, Nelson Lopez-Sejas, Carmen Campos, Beatriz Sanchez-Correa, Raquel Tarazona, Alejandra Pera

Int J Mol Sci· June 2017

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