Publications by authors named "Alejandro Adam"

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Endothelial cells retain inflammatory memory through chromatin remodeling in a two-hit model of infection-induced inflammation.
Daniel Gonsales Spindola, Amber Bahr, Samantha Clark, Gabriel Pin de Jesus, Nina Martino, Alejandro P Adam

Am J Physiol Cell Physiol· December 2025

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Endothelial STING and STAT1 mediate IFN-independent effects of IL-6 in an endotoxemia-induced model of shock.
Nina Martino, Erin K Sanders, Ramon Bossardi Ramos, Iria Di John Portela, Fatma Awadalla, Alejandro P Adam

J Clin Invest· November 2025

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Distinguishing Periorbital Necrotizing Fasciitis from Orbital Cellulitis Using Admission Laboratory Values.
Mitchell J Rheeman, Michael I Rothschild, Michael J Pokabla, Alejandro P Adam, Edward J Wladis

Ophthalmic Plast Reconstr Surg· November 2025

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Endothelial Cell Stimulator of Interferon Genes Regulates IL-6 Production and Is Required for Pathologic Cardiac Hypertrophy and Contractile Dysfunction in Experimental Heart Failure.
Erin Sanders, Kuljeet Kaur, Noah Wagner, Ramona Emig, Mark Aronovitz, Alejandro P Adam

Am J Pathol· October 2025

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Derived Neutrophil-to-Lymphocyte and Neutrophil-to-Platelet Ratios Distinguish Sinusitis-Related Orbital Cellulitis From Periorbital Necrotizing Fasciitis.
Edward J Wladis, Colin LeSage, Maria Paez, Jordon G Grube, Michael J Pokabla, Alejandro P Adam

Ophthalmic Plast Reconstr Surg· July 2025

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New therapies for unresectable or metastatic cutaneous eyelid and orbital melanoma.
Edward J Wladis, Michael I Rothschild, Carisa E Bohnak, Alejandro P Adam

Orbit· February 2025

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LRRC8A-containing anion channels promote glioblastoma proliferation via a WNK1/mTORC2-dependent mechanism.
Antonio M Fidaleo, Martin D Bach, Shaina Orbeta, Iskandar F Abdullaev, Nina Martino, Alejandro P Adam

bioRxiv· February 2025

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A transient brain endothelial translatome response to endotoxin is associated with mild cognitive changes post-shock in young mice.
Shuhan Lu, Iria Di John Portela, Nina Martino, Ramon Bossardi Ramos, Abigail E Salinero, Alejandro P Adam

Neuroscience· September 2024

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Reply Re: "Neutrophil-to-Lymphocyte Ratios Distinguish Idiopathic Orbital Inflammation From Orbital Infectious Disease".
Edward J Wladis, Carisa E Bohnak, James J Law, Alejandro P Adam, Michael I Rothschild

Ophthalmic Plast Reconstr Surg· July 2024

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A transient brain endothelial translatome response to endotoxin is associated with mild cognitive changes post-shock in young mice.
Shuhan Lu, Iria Di John Portela, Nina Martino, Ramon Bossardi Ramos, Abigail E Salinero, Alejandro P Adam

bioRxiv· May 2024

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Safety and tolerability of topical trametinib in rosacea: Results from a phase I clinical trial.
Edward J Wladis, Jacqueline Busingye, Leahruth K Saavedra, Amy Murdico, Alejandro P Adam

Skin Health Dis· April 2024

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Neutrophil-to-Lymphocyte Ratios Distinguish Idiopathic Orbital Inflammation From Orbital Infectious Disease.
Edward J Wladis, Carisa E Bohnak, James J Law, Alejandro P Adam, Michael I Rothschild

Ophthalmic Plast Reconstr Surg· March 2024

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DMT1-dependent endosome-mitochondria interactions regulate mitochondrial iron translocation and metastatic outgrowth.
Jonathan Barra, Isaiah Crosbourne, Cassandra L Roberge, Ramon Bossardi-Ramos, Janine S A Warren, Alejandro P Adam

Oncogene· February 2024

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Helical vasculogenesis driven by cell chirality.
Haokang Zhang, Tasnif Rahman, Shuhan Lu, Alejandro Pablo Adam, Leo Q Wan

Sci Adv· February 2024

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Resolvin D2-G-Protein Coupled Receptor 18 Enhances Bone Marrow Function and Limits Steatosis and Hepatic Collagen Accumulation in Aging.
Hannah Fitzgerald, Jesse L Bonin, Sayeed Khan, Maya Eid, Sudeshna Sadhu, Alejandro P Adam

Am J Pathol· December 2023

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Shock drives a STAT3 and JunB-mediated coordinated transcriptional and DNA methylation response in the endothelium.
Ramon Bossardi Ramos, Nina Martino, Dareen Chuy, Shuhan Lu, Mei Xing G Zuo, Alejandro P Adam

J Cell Sci· September 2023

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Emerging therapeutic options for periorbital and orbital cutaneous basal and squamous cell carcinomas.
Edward J Wladis, Stephen H Wrzesinski, Michael I Rothschild, Alejandro P Adam

Orbit· April 2023

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SH2 domain-containing protein tyrosine phosphatase-2 is enriched in eyelid specimens of rosacea.
Apoorv Chebolu, Ramon Bossardi Ramos, Thilaka Arunachalam, Alejandro Pablo Adam, Edward J Wladis

Skin Health Dis· February 2023

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The Resolvin D2-GPR18 Axis Enhances Bone Marrow Function and Limits Hepatic Fibrosis in Aging.
Hannah Fitzgerald, Jesse L Bonin, Sudeshna Sadhu, Masharh Lipscomb, Nirupam Biswas, Alejandro Adam

bioRxiv· January 2023

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SOCS3 limits TNF and endotoxin-induced endothelial dysfunction by blocking a required autocrine interleukin-6 signal in human endothelial cells.
Nina Martino, Ramon Bossardi Ramos, Dareen Chuy, Lindsay Tomaszek, Alejandro P Adam

Am J Physiol Cell Physiol· August 2022

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Myeloid differentiation factor 88 expression in eyelid specimens of rosacea.
Edward J Wladis, Thilaka Arunachalam, Juliann E LaJoie, Kevin W Lau, Alejandro P Adam

Orbit· June 2022

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Immune signaling in rosacea.
Edward J Wladis, Alejandro P Adam

Ocul Surf· October 2021

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Endothelial SOCS3 maintains homeostasis and promotes survival in endotoxemic mice.
Nina Martino, Ramon Bossardi Ramos, Shuhan Lu, Kara Leyden, Lindsay Tomaszek, Alejandro P Adam

JCI Insight· July 2021

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Molecular Mechanisms of Vascular Damage During Lung Injury.
Ramon Bossardi Ramos, Alejandro Pablo Adam

Adv Exp Med Biol· May 2021

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CaMKIIδ is upregulated by pro-inflammatory cytokine IL-6 in a JAK/STAT3-dependent manner to promote angiogenesis.
Brendan J O'Brien, Harold A Singer, Alejandro P Adam, Roman G Ginnan

FASEB J· April 2021

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