Publications by authors named "Alejandro Couce"

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Idiosyncratic evolvability among single-point ribosomal mutants towards multi-aminoglycoside resistance.
Laura Sánchez-Maroto, Guillem A Devin, Pablo Gella, Alejandro Couce

PLoS Genet· August 2025

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Cryptic phenotypic variation emerges rapidly during the adaptive evolution of a carbapenemase.
Laura Dabos, Inssaf Nedjari, Alejandro Couce

Nat Ecol Evol· July 2025

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Mutualism breakdown underpins evolutionary rescue in an obligate cross-feeding bacterial consortium.
Ignacio J Melero-Jiménez, Yael Sorokin, Ami Merlin, Jiawei Li, Alejandro Couce

Nat Commun· April 2025

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The evolution of robustness and fragility during long-term bacterial adaptation.
Doha Chihoub, Coralie Pintard, Richard E Lenski, Olivier Tenaillon, Alejandro Couce

Proc Natl Acad Sci U S A· April 2025

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Regulatory networks may evolve to favor adaptive foresight.
Alejandro Couce

PLoS Biol· December 2024

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Novel Fosfomycin Resistance Mechanism in Due to Atypical Pho Regulon Control of GlpT.
Laura Sánchez-Maroto, Pablo Gella, Alejandro Couce

Antibiotics (Basel)· October 2024

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Changing fitness effects of mutations through long-term bacterial evolution.
Alejandro Couce, Anurag Limdi, Melanie Magnan, Siân V Owen, Cristina M Herren

Science· January 2024

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Editorial: Integrating multi-scale approaches for predicting microbiome ecology and evolution.
Andrea Quagliariello, Ricardo S Ramiro, Alejandro Couce, Maria Elena Martino

Front Microbiol· October 2022

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Flux, toxicity, and expression costs generate complex genetic interactions in a metabolic pathway.
Harry Kemble, Catherine Eisenhauer, Alejandro Couce, Audrey Chapron, Mélanie Magnan

Sci Adv· June 2020

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Mutation bias and GC content shape antimutator invasions.
Alejandro Couce, Olivier Tenaillon

Nat Commun· July 2019

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Parallel Evolution of High-Level Aminoglycoside Resistance in Under Low and High Mutation Supply Rates.
Claudia Ibacache-Quiroga, Juan C Oliveros, Alejandro Couce, Jesus Blázquez

Front Microbiol· March 2018

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Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria.
Alejandro Couce, Larissa Viraphong Caudwell, Christoph Feinauer, Thomas Hindré, Jean-Paul Feugeas

Proc Natl Acad Sci U S A· October 2017

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Correction to 'Bypass of genetic constraints during mutator evolution to antibiotic resistance'.
Alejandro Couce, Alexandro Rodríguez-Rojas, Jesús Blázquez

Proc Biol Sci· August 2016

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Determinants of Genetic Diversity of Spontaneous Drug Resistance in Bacteria.
Alejandro Couce, Alexandro Rodríguez-Rojas, Jesús Blázquez

Genetics· July 2016

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Bypass of genetic constraints during mutator evolution to antibiotic resistance.
Alejandro Couce, Alexandro Rodríguez-Rojas, Jesús Blázquez

Proc Biol Sci· April 2015

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The rule of declining adaptability in microbial evolution experiments.
Alejandro Couce, Olivier A Tenaillon

Front Genet· March 2015

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Antibiotics and antibiotic resistance: a bitter fight against evolution.
Alexandro Rodríguez-Rojas, Jerónimo Rodríguez-Beltrán, Alejandro Couce, Jesús Blázquez

Int J Med Microbiol· August 2013

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Mutational spectrum drives the rise of mutator bacteria.
Alejandro Couce, Javier R Guelfo, Jesús Blázquez

PLoS Genet· May 2013

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Antimicrobials as promoters of genetic variation.
Jesús Blázquez, Alejandro Couce, Jerónimo Rodríguez-Beltrán, Alexandro Rodríguez-Rojas

Curr Opin Microbiol· October 2012

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The Escherichia coli SOS gene dinF protects against oxidative stress and bile salts.
Jerónimo Rodríguez-Beltrán, Alexandro Rodríguez-Rojas, Javier R Guelfo, Alejandro Couce, Jesús Blázquez

PLoS One· August 2012

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Genomewide overexpression screen for fosfomycin resistance in Escherichia coli: MurA confers clinical resistance at low fitness cost.
Alejandro Couce, Alejandra Briales, Alexandro Rodríguez-Rojas, Coloma Costas, Alvaro Pascual

Antimicrob Agents Chemother· May 2012

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Estimating mutation rates in low-replication experiments.
Alejandro Couce, Jesús Blázquez

Mutat Res· September 2011

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Effect of recA inactivation on mutagenesis of Escherichia coli exposed to sublethal concentrations of antimicrobials.
Thuy Do Thi, Elena López, Alexandro Rodríguez-Rojas, Jerónimo Rodríguez-Beltrán, Alejandro Couce

J Antimicrob Chemother· March 2011

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Frequency of spontaneous resistance to fosfomycin combined with different antibiotics in Pseudomonas aeruginosa.
Alexandro Rodríguez-Rojas, Alejandro Couce, Jesús Blázquez

Antimicrob Agents Chemother· November 2010

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Assessing the emergence of resistance: the absence of biological cost in vivo may compromise fosfomycin treatments for P. aeruginosa infections.
Alexandro Rodríguez-Rojas, María D Maciá, Alejandro Couce, Cristina Gómez, Alfredo Castañeda-García

PLoS One· April 2010

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