Publications by authors named "Alejandro Dorenbaum"

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Characterization of Fatigue in Primary Mitochondrial Myopathies: Findings From a Qualitative Interview Study.
Amel Karaa, Nathan Johnson, Ian Clarkson, Wendy Newman, Alejandro Dorenbaum

Neurol Clin Pract· February 2024

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Safety, tolerability, and efficacy of maralixibat in adults with primary sclerosing cholangitis: Open-label pilot study.
Christopher L Bowlus, Bertus Eksteen, Angela C Cheung, Douglas Thorburn, Cynthia A Moylan, Alejandro Dorenbaum

Hepatol Commun· June 2023

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Maralixibat for the treatment of PFIC: Long-term, IBAT inhibition in an open-label, Phase 2 study.
Kathleen M Loomes, Robert H Squires, Deirdre Kelly, Sanjay Rajwal, Nisreen Soufi, Alejandro Dorenbaum

Hepatol Commun· September 2022

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Treatment of VLCAD-Deficient Patient Fibroblasts with Peroxisome Proliferator-Activated Receptor δ Agonist Improves Cellular Bioenergetics.
Olivia M D'Annibale, Yu Leng Phua, Clinton Van't Land, Anuradha Karunanidhi, Alejandro Dorenbaum

Cells· August 2022

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Efficacy and safety of maralixibat treatment in patients with Alagille syndrome and cholestatic pruritus (ICONIC): a randomised phase 2 study.
Emmanuel Gonzales, Winita Hardikar, Michael Stormon, Alastair Baker, Loreto Hierro, Alejandro Dorenbaum

Lancet· October 2021

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A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis.
Marlyn J Mayo, Paul J Pockros, David Jones, Christopher L Bowlus, Cynthia Levy, Alejandro Dorenbaum

Hepatol Commun· March 2019

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Development of a Novel Tool to Assess the Impact of Itching in Pediatric Cholestasis.
Binita M Kamath, Linda Abetz-Webb, Ciara Kennedy, Bonnie Hepburn, Martha Gauthier, Alejandro Dorenbaum

Patient· February 2018

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Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial.
Renger G Tiessen, Ciara A Kennedy, Bradley T Keller, Nancy Levin, Lisette Acevedo, Alejandro Dorenbaum

BMC Gastroenterol· January 2018

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Impact of asthma exacerbations and asthma triggers on asthma-related quality of life in patients with severe or difficult-to-treat asthma.
Allan T Luskin, Bradley E Chipps, Lawrence Rasouliyan, Dave P Miller, Tmirah Haselkorn, Alejandro Dorenbaum

J Allergy Clin Immunol Pract· May 2015

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Single-dose, subcutaneous recombinant phenylalanine ammonia lyase conjugated with polyethylene glycol in adult patients with phenylketonuria: an open-label, multicentre, phase 1 dose-escalation trial.
Nicola Longo, Cary O Harding, Barbara K Burton, Dorothy K Grange, Jerry Vockley, Alejandro Dorenbaum

Lancet· July 2014

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Phenotypes determined by cluster analysis in severe or difficult-to-treat asthma.
Michael Schatz, Jin-Wen Y Hsu, Robert S Zeiger, Wansu Chen, Alejandro Dorenbaum

J Allergy Clin Immunol· June 2014

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Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4-6 asthma therapy in the TENOR cohort.
William J Calhoun, Tmirah Haselkorn, David R Mink, Dave P Miller, Alejandro Dorenbaum

J Allergy Clin Immunol Pract· May 2014

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Chaperone-like therapy with tetrahydrobiopterin in clinical trials for phenylketonuria: is genotype a predictor of response?
Christineh N Sarkissian, Alejandra Gamez, Patrick Scott, Jerome Dauvillier, Alejandro Dorenbaum

JIMD Rep· February 2013

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Assessment of asthma control and asthma exacerbations in the epidemiology and natural history of asthma: outcomes and treatment regimens (TENOR) observational cohort.
Bradley E Chipps, Robert S Zeiger, Alejandro Dorenbaum, Larry Borish, Sally E Wenzel

Curr Respir Care Rep· December 2012

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Efficacy and safety of heparinase I versus protamine in patients undergoing coronary artery bypass grafting with and without cardiopulmonary bypass.
Mark Stafford-Smith, Edward A Lefrak, Anjum G Qazi, Ian J Welsby, Linda Barber, Alejandro Dorenbaum

Anesthesiology· August 2005

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Maternal toxicity and pregnancy complications in human immunodeficiency virus-infected women receiving antiretroviral therapy: PACTG 316.
D Heather Watts, Rajalakshmi Balasubramanian, Robert T Maupin, Isaac Delke, Alejandro Dorenbaum

Am J Obstet Gynecol· February 2004

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Predose infant nevirapine concentration with the two-dose intrapartum neonatal nevirapine regimen: association with timing of maternal intrapartum nevirapine dose.
Mark Mirochnick, Alejandro Dorenbaum, Suzette Blanchard, Coleen K Cunningham, Richard D Gelber

J Acquir Immune Defic Syndr· June 2003

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When the time comes to talk about HIV: factors associated with diagnostic disclosure and emotional distress in HIV-infected children.
Patricia Lester, Margaret Chesney, Molly Cooke, Robert Weiss, Patrick Whalley, Alejandro Dorenbaum

J Acquir Immune Defic Syndr· November 2002

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Envelope-based HIV vaccines.
John J Donnelly, Susan W Barnett, Alejandro Dorenbaum, Leonidas Stamatatos

Science· August 2002

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Two-dose intrapartum/newborn nevirapine and standard antiretroviral therapy to reduce perinatal HIV transmission: a randomized trial.
Alejandro Dorenbaum, Coleen K Cunningham, Richard D Gelber, Mary Culnane, Lynne Mofenson

JAMA· July 2002

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Development of resistance mutations in women receiving standard antiretroviral therapy who received intrapartum nevirapine to prevent perinatal human immunodeficiency virus type 1 transmission: a substudy of pediatric AIDS clinical trials group protocol 316.
Coleen K Cunningham, Marie-Laure Chaix, Claire Rekacewicz, Paula Britto, Christine Rouzioux, Alejandro Dorenbaum

J Infect Dis· July 2002

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