Publications by authors named "Alejandro Schijman"

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Ultra-Rapid DNA Extraction Coupled with Loop-Mediated Isothermal Amplification for Point-of-Care Detection of Trypanosoma cruzi Infection in Heparinized Blood and Dried Blood Spots.
Silvia A Longhi, Lady J García-Casares, Arturo A Muñoz-Calderón, Julio Alonso-Padilla, Alejandro G Schijman

Methods Mol Biol· November 2025

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Quantifying anti-trypanosomal treatment effects in chronic indeterminate Chagas disease: a secondary analysis of individual patient data from two proof-of-concept trials.
James A Watson, Cintia Cruz, Fabiana Barreira, Colin Forsyth, Alejandro G Schijman

Lancet Microbe· October 2025

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Diagnosis of Trypanosoma cruzi infection in Mexican populations: current conventional serology lacks adequate sensitivity and specificity.
Janine M Ramsey, Keynes de la Cruz-Felix, Ezequiel Tun-Ku, Alejandro G Schijman, Sleidher Gutiérrez

Mem Inst Oswaldo Cruz· October 2025

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New regimens of benznidazole for the treatment of chronic Chagas disease in adult participants in indeterminate form or with mild cardiac progression (NuestroBen study): protocol for a phase III randomised, multicentre non-inferiority clinical trial.
Tayná Marques, Colin Forsyth, Fabiana Barreira, Carola Lombas, Bethania Blum de Oliveira, Alejandro Schijman

BMJ Open· September 2025

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Interlaboratory Harmonization Study and Prospective Evaluation of the PURE-Trypanosoma cruzi-Loop-Mediated Isothermal Amplification Assay for Detecting Parasite DNA in Newborn's Dried Blood Spots.
Silvia A Longhi, Lady J García-Casares, Arturo Muñoz-Calderón, Lucía Irazu, Marcelo A Rodríguez, Alejandro G Schijman

J Mol Diagn· December 2024

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Evaluation and validation of a PrintrLab-based LAMP assay to identify Trypanosoma cruzi in newborns in Bolivia: a proof-of-concept study.
Lizeth Rojas Panozo, Silvia Rivera Nina, Diana P Wehrendt, Aina Casellas, Lilian Pinto, Alejandro G Schijman

Lancet Microbe· September 2024

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Retrospect, advances and challenges in Chagas disease diagnosis: a comprehensive review.
Alejandro Gabriel Schijman, Julio Alonso-Padilla, Constança Britto, Claudia Patricia Herrera Bernal

Lancet Reg Health Am· August 2024

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A standardized clinical database for research in Chagas disease: The NHEPACHA network.
Adriana González Martínez, Irene Losada-Galván, Juan Carlos Gabaldón-Figueira, Nieves Martínez-Peinado, Roberto Magalhães Saraiva, Alejandro Gabriel Schijman

PLoS Negl Trop Dis· August 2024

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A guide for the generation of repositories of clinical samples for research on Chagas disease.
Nieves Martínez-Peinado, Juan Carlos Gabaldón-Figueira, Roberto Rodrigues Ferreira, María Carmen Thomas, Manuel Carlos López, Alejandro Gabriel Schijman

PLoS Negl Trop Dis· August 2024

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Novel 3D human trophoblast culture to explore infection in the placenta.
Sofia Apodaca, Marco Di Salvatore, Arturo Muñoz-Calderón, María de Los Ángeles Curto, Silvia A Longhi, Alejandro G Schijman

Front Cell Infect Microbiol· August 2024

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Zoonotic Cycle of American Trypanosomiasis in an Endemic Region of the Argentine Chaco, Factors That Influenced a Paradigm Shift.
Andrea Gómez-Bravo, Sebastián Cirignoli, Diana Wehrendt, Alejandro Schijman, Cielo M León

Insects· June 2024

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Quantitative PCR-Based Diagnosis and Follow-up of Chagas Disease Primary Infection After Solid Organ Transplant: A Multicentre Study.
Laura A Barcan, Astrid Smud, Susana A Besuschio, Patricia L Giorgio, Elena Temporiti, Alejandro G Schijman

J Infect Dis· November 2023

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Practical diagnostic algorithms for Chagas disease: a focus on low resource settings.
Juan Carlos Gabaldón-Figueira, Malia Skjefte, Silvia Longhi, Elisa Escabia, Lady Juliette García, Alejandro Gabriel Schijman

Expert Rev Anti Infect Ther· November 2023

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Unveiling challenges in real-time PCR strategies for detecting treatment failure: observations from clinical trials on chronic Chagas disease.
Alejandro G Schijman

Front Parasitol· September 2023

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Molecular Characterization of Reactivation and Follow-up in a Case Series of People With HIV.
Marisa Liliana Fernandez, Constanza Lopez Albizu, Diego Nicita, Susana Besuschio, Cinthia Giomi, Alejandro Schijman

Open Forum Infect Dis· August 2023

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Combination of ultra-rapid DNA purification (PURE) and loop-mediated isothermal amplification (LAMP) for rapid detection of Trypanosoma cruzi DNA in dried blood spots.
Silvia A Longhi, Lady J García Casares, Arturo A Muñoz-Calderón, Julio Alonso-Padilla, Alejandro G Schijman

PLoS Negl Trop Dis· April 2023

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Genetic Characterization of I Populations from an Oral Chagas Disease Outbreak in Venezuela: Natural Resistance to Nitroheterocyclic Drugs.
Arturo Muñoz-Calderón, José Luis Ramírez, Zoraida Díaz-Bello, Belkisyolé Alarcón de Noya, Oscar Noya, Alejandro G Schijman

ACS Infect Dis· March 2023

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A Phase 2, Randomized, Multicenter, Placebo-Controlled, Proof-of-Concept Trial of Oral Fexinidazole in Adults With Chronic Indeterminate Chagas Disease.
Faustino Torrico, Joaquim Gascón, Lourdes Ortiz, Jimy Pinto, Gimena Rojas, Alejandro Gabriel Schijman

Clin Infect Dis· February 2023

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Molecular detection and parasite load of Trypanosoma cruzi in digestive tract tissue of Chagas disease patients affected by megacolon.
Lilian Pinto, Alejandro G Schijman, Julio Alonso-Padilla, Daniel Lozano, Mary Cruz Torrico

Acta Trop· November 2022

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Parasitological, serological and molecular diagnosis of acute and chronic Chagas disease: from field to laboratory.
Alejandro Gabriel Schijman, Julio Alonso-Padilla, Silvia Andrea Longhi, Albert Picado

Mem Inst Oswaldo Cruz· May 2022

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Loop-Mediated Isothermal Amplification of DNA for Point-of-Care Follow-Up of Anti-Parasitic Treatment of Chagas Disease.
Arturo A Muñoz-Calderón, Susana A Besuschio, Season Wong, Marisa Fernández, Lady J García Cáceres, Alejandro G Schijman

Microorganisms· April 2022

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Genetic polymorphism of Trypanosoma cruzi bloodstream populations in adult chronic indeterminate Chagas disease patients from the E1224 clinical trial.
Juan Carlos Ramírez, Gonzalo Raúl Acevedo, Carolina Torres, Rudy Parrado, Anabelle De La Barra, Alejandro Gabriel Schijman

J Antimicrob Chemother· February 2022

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New chemotherapy regimens and biomarkers for Chagas disease: the rationale and design of the TESEO study, an open-label, randomised, prospective, phase-2 clinical trial in the Plurinational State of Bolivia.
Cristina Alonso-Vega, Julio A Urbina, Sergi Sanz, María-Jesús Pinazo, Jimy José Pinto, Alejandro Schijman

BMJ Open· December 2021

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Differential tissue distribution of discrete typing units after drug combination therapy in experimental mixed infection.
Mariana Strauss, M Silvina Lo Presti, Juan C Ramírez, P Carolina Bazán, Daniela A Velázquez López, Alejandro G Schijman

Parasitology· November 2021

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Prospective multicenter evaluation of real time PCR Kit prototype for early diagnosis of congenital Chagas disease.
Alejandro Francisco Benatar, Emmaría Danesi, Susana Alicia Besuschio, Santiago Bortolotti, María Luisa Cafferata, Alejandro Gabriel Schijman

EBioMedicine· July 2021

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