Publications by authors named "Alena Heimsoeth"

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Functional synapses between neurons and small cell lung cancer.
Vignesh Sakthivelu, Anna Schmitt, Franka Odenthal, Kristiano Ndoci, Marian Touet, Alena Heimsoeth

Nature· October 2025

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Publisher Correction: Functional synapses between neurons and small cell lung cancer.
Vignesh Sakthivelu, Anna Schmitt, Franka Odenthal, Kristiano Ndoci, Marian Touet, Alena Heimsoeth

Nature· October 2025

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Characterizing Evolutionary Dynamics Reveals Strategies to Exhaust the Spectrum of Subclonal Resistance in EGFR-Mutant Lung Cancer.
Nina Müller, Carina Lorenz, Jenny Ostendorp, Felix S Heisel, Ulrich P Friese, Alena Heimsoeth

Cancer Res· August 2023

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Resistance to MET inhibition in MET-dependent NSCLC and therapeutic activity after switching from type I to type II MET inhibitors.
Richard Riedel, Jana Fassunke, Hannah L Tumbrink, Andreas H Scheel, Carina Heydt, Alena Heimsoeth

Eur J Cancer· January 2023

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Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors.
Jonas Lategahn, Hannah L Tumbrink, Carsten Schultz-Fademrecht, Alena Heimsoeth, Lisa Werr

J Med Chem· May 2022

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MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
Johannes Brägelmann, Carina Lorenz, Sven Borchmann, Kazuya Nishii, Julia Wegner, Alena Heimsoeth

Nat Commun· September 2021

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The next tier of EGFR resistance mutations in lung cancer.
Hannah L Tumbrink, Alena Heimsoeth, Martin L Sos

Oncogene· January 2021

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Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S.
Jonas Lategahn, Marina Keul, Philip Klövekorn, Hannah L Tumbrink, Janina Niggenaber, Alena Heimsoeth

Chem Sci· December 2019

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TCam-2 Cells Deficient for SOX2 and FOXA2 Are Blocked in Differentiation and Maintain a Seminoma-Like Cell Fate In Vivo.
Daniel Nettersheim, Saskia Vadder, Sina Jostes, Alena Heimsoeth, Hubert Schorle

Cancers (Basel)· May 2019

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Overcoming EGFR-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors.
Jana Fassunke, Fabienne Müller, Marina Keul, Sebastian Michels, Marcel A Dammert, Alena Heimsoeth

Nat Commun· November 2018

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SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate.
Daniel Nettersheim, Alena Heimsoeth, Sina Jostes, Simon Schneider, Martin Fellermeyer

Oncotarget· July 2016

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