Publications by authors named "Ales Strancar"

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Analysis of lipid nanoparticles using two-dimensional chromatography: Simultaneous determination of encapsulation efficiency, nucleic acid integrity, and size of LNP formulations.
Nejc Pavlin, Mojca Bavčar, Tristan Kovačič, Tjaša Kašček, Anže Martinčič Celjar

J Chromatogr B Analyt Technol Biomed Life Sci· November 2025

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The impact of chemical reactivity on the quality and stability of RNA-LNP pharmaceuticals.
Tristan Kovačič, Heinrich Haas, Lior Stotsky-Oterin, Aleš Štrancar, Urban Bren

Nat Rev Chem· November 2025

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Enhanced Separation of AAV Capsids Using Analytical Anion Exchange Monolithic Columns: Emphasis on Organic Modifiers.
Timotej Žvanut, Sebastijan Peljhan, Sergeja Lebar, Aleš Štrancar, Andreja Gramc Livk

Anal Chim Acta· November 2025

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Comprehensive Characterisation of Extracellular Vesicle Preparations Using Multiparametric Size-Exclusion Chromatography.
Darja Božič, Katja Vrabec, Ana Železnik, Andrej Raspor, Valentina Novak

Int J Mol Sci· August 2025

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Reverse-phase chromatography removes double-stranded RNA, fragments, and residual template to decrease immunogenicity and increase cell potency of mRNA and saRNA.
Andreja Krušič, Nina Mencin, Marta Leban, Evelin Nett, Mario Perković

Mol Ther Nucleic Acids· June 2025

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Development and Validation of AAV Capsids Separation on Specimen Columns for Reproducibility Evaluation of Large-Scale Chromatographic Monoliths.
Rok Miklavčič, Tina Simčič, Sara Rotar, Polona Komel, Rok Žigon

J Sep Sci· March 2025

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Selective hydrophobic interaction chromatography for high purity of supercoiled DNA plasmids.
Klemen Božič, Ajda Sedlar, Špela Kralj, Urh Černigoj, Aleš Štrancar

Biotechnol Bioeng· May 2024

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Determination of linearized pDNA template in mRNA production process using HPLC.
Marta Leban, Tina Vodopivec Seravalli, Martina Hauer, Ernst Böhm, Nina Mencin

Anal Bioanal Chem· April 2024

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Bridging upstream and downstream for improved adenovirus 5 bioprocess.
Ivana Petrović Koshmak, Hana Jug, Katja Vrabec, Ana Mavri, Valentina Novak

Electrophoresis· March 2024

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Analytical separation of plasmid DNA isoforms using anion exchanging chromatographic monoliths with 6 µm channels.
Nejc Pavlin, Urh Černigoj, Mojca Bavčar, Tjaša Plesničar, Jan Mavri

Electrophoresis· December 2023

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Effect of plasmid DNA isoforms on preparative anion exchange chromatography.
Špela Kralj, Špela Meta Kodermac, Ines Bergoč, Tomas Kostelec, Aleš Podgornik

Electrophoresis· December 2023

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Preferential exclusion chromatography as a capture step for extracellular AAV harvest from adherent and suspension productions.
Maja Leskovec, Andrej Raspor, Veronika Fujs, Andrej Mihevc, Aleš Štrancar

Electrophoresis· December 2023

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Optimization of rAAV capture step purification using SO3 monolith chromatography.
Kaja Bažec, Mirjam Krašna, Andrej Mihevc, Maja Leskovec, Aleš Štrancar

Electrophoresis· December 2023

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Scalable multimodal weak anion exchange chromatographic purification for stable mRNA drug substance.
Polona Megušar, Rok Miklavčič, Matevž Korenč, Jure Ličen, Tina Vodopivec

Electrophoresis· December 2023

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High Recovery Chromatographic Purification of mRNA at Room Temperature and Neutral pH.
Rok Miklavčič, Polona Megušar, Špela Meta Kodermac, Blaž Bakalar, Darko Dolenc

Int J Mol Sci· September 2023

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Increasing yield of in vitro transcription reaction with at-line high pressure liquid chromatography monitoring.
Domen Pregeljc, Janja Skok, Tina Vodopivec, Nina Mencin, Andreja Krušič

Biotechnol Bioeng· March 2023

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Comparative analysis of transferrin and IgG N-glycosylation in two human populations.
Irena Trbojević-Akmačić, Frano Vučković, Tea Pribić, Marija Vilaj, Urh Černigoj

Commun Biol· March 2023

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High-throughput immunoaffinity enrichment and N-glycan analysis of human plasma haptoglobin.
Jelena Šimunović, Jernej Gašperšič, Urh Černigoj, Jana Vidič, Aleš Štrancar

Biotechnol Bioeng· February 2023

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CIM monolithic chromatography as a useful tool for endotoxin reduction and purification of bacteriophage particles supported with PAT analytics.
Lucija Rebula, Andrej Raspor, Mojca Bavčar, Aleš Štrancar, Maja Leskovec

J Chromatogr B Analyt Technol Biomed Life Sci· February 2023

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Sample displacement chromatography of monoclonal antibody charge variants and aggregates.
Urh Černigoj, Blaž Nemec, Aleš Štrancar

Electrophoresis· February 2022

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Guanidine improves DEAE anion exchange-based analytical separation of plasmid DNA.
Urh Černigoj, Jana Vidič, Ana Ferjančič, Urša Sinur, Klemen Božič

Electrophoresis· December 2021

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Removal of empty capsids from adeno-associated virus preparations by multimodal metal affinity chromatography.
Pete Gagnon, Maja Leskovec, Sara Drmota Prebil, Rok Žigon, Maja Štokelj

J Chromatogr A· July 2021

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Scale-Up of Plasmid DNA Downstream Process Based on Chromatographic Monoliths.
Urh Černigoj, Aleš Štrancar

Methods Mol Biol· March 2021

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Multiple-Monitor HPLC Assays for Rapid Process Development, In-Process Monitoring, and Validation of AAV Production and Purification.
Pete Gagnon, Blaz Goricar, Nina Mencin, Timotej Zvanut, Sebastijan Peljhan, Ales Strancar

Pharmaceutics· January 2021

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The development of a monolith-based purification process for Orthopoxvirus vaccinia virus Lister strain.
David Vincent, Petra Kramberger, Rosana Hudej, Aleš Štrancar, Yaohe Wang

J Chromatogr A· November 2017

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