Publications by authors named "Alessandra Ottani"

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Supra-Physiological Levels of Magnesium Counteract the Inhibitory Effect of Zoledronate on RANKL-Dependent Osteoclastogenesis.
Lorenzo Caselli, Lisa De Pasquale, Rossella Palumbo, Silvia Ricchiuto, Monica Montanari, Alessandra Ottani

Biology (Basel)· May 2025

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Melanocortin-4 Receptor Antagonism Inhibits Colorectal and Anaplastic Thyroid Cancer In Vitro and In Vivo.
Arianna Bandini, Marta Banchi, Paola Orlandi, Francesca Vaglini, Greta Alì, Alessandra Ottani

J Clin Med· February 2025

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Melanocortin receptor 4 as a new target in melanoma therapy: Anticancer activity of the inhibitor ML00253764 alone and in association with B-raf inhibitor vemurafenib.
Paola Orlandi, Marta Banchi, Francesca Vaglini, Marco Carli, Stefano Aringhieri, Alessandra Ottani

Biochem Pharmacol· January 2024

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Corrigendum to "Modulation of the JAK/ERK/STAT signaling in melanocortin -induced inhibition of local and systemic responses to myocardial ischemia/reperfusion [Pharmacological Research 72 (2013) 1-8].
Alessandra Ottani, Maria Galantucci, Ettore Ardimento, Laura Neri, Fabrizio Canalini

Pharmacol Res· August 2023

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Melanocortin receptor agonist NDP-α-MSH improves cognitive deficits and microgliosis but not amyloidosis in advanced stages of AD progression in 5XFAD and 3xTg mice.
Eleonora Daini, Eleonora Vandini, Martina Bodria, Wenjie Liao, Carlo Baraldi, Alessandra Ottani

Front Immunol· January 2023

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Oxidative Stress in Alzheimer's Disease: Therapeutic Effect of Amniotic Fluid Stem Cells Extracellular Vesicles.
Martina Gatti, Manuela Zavatti, Francesca Beretti, Daniela Giuliani, Eleonora Vandini, Alessandra Ottani

Oxid Med Cell Longev· May 2021

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Mechanisms of Hydrogen Sulfide against the Progression of Severe Alzheimer's Disease in Transgenic Mice at Different Ages.
Eleonora Vandini, Alessandra Ottani, Davide Zaffe, Anita Calevro, Fabrizio Canalini

Pharmacology· March 2019

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Melanocortin Receptor-4 and Glioblastoma Cells: Effects of the Selective Antagonist ML00253764 Alone and in Combination with Temozolomide In Vitro and In Vivo.
Francesca Vaglini, Carla Pardini, Teresa Di Desidero, Paola Orlandi, Francesco Pasqualetti, Alessandra Ottani

Mol Neurobiol· June 2018

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Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice.
Alessandra Bitto, Daniela Giuliani, Giovanni Pallio, Natasha Irrera, Eleonora Vandini, Alessandra Ottani

Inflamm Res· May 2017

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Multiple beneficial effects of melanocortin MC receptor agonists in experimental neurodegenerative disorders: Therapeutic perspectives.
Daniela Giuliani, Alessandra Ottani, Laura Neri, Davide Zaffe, Paolo Grieco

Prog Neurobiol· January 2017

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NDP-α-MSH attenuates heart and liver responses to myocardial reperfusion via the vagus nerve and JAK/ERK/STAT signaling.
Alessandra Ottani, Daniela Giuliani, Laura Neri, Anita Calevro, Fabrizio Canalini

Eur J Pharmacol· December 2015

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NDP-α-MSH induces intense neurogenesis and cognitive recovery in Alzheimer transgenic mice through activation of melanocortin MC4 receptors.
Daniela Giuliani, Laura Neri, Fabrizio Canalini, Anita Calevro, Alessandra Ottani

Mol Cell Neurosci· July 2015

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Protective effects of the melanocortin analog NDP-α-MSH in rats undergoing cardiac arrest.
Alessandra Ottani, Laura Neri, Fabrizio Canalini, Anita Calevro, Rosario Rossi

Eur J Pharmacol· December 2014

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Melanocortins protect against brain damage and counteract cognitive decline in a transgenic mouse model of moderate Alzheimer׳s disease.
Daniela Giuliani, Maria Galantucci, Laura Neri, Fabrizio Canalini, Anita Calevro, Alessandra Ottani

Eur J Pharmacol· October 2014

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Melanocortins protect against progression of Alzheimer's disease in triple-transgenic mice by targeting multiple pathophysiological pathways.
Daniela Giuliani, Alessandra Bitto, Maria Galantucci, Davide Zaffe, Alessandra Ottani

Neurobiol Aging· March 2014

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Hydrogen sulfide slows down progression of experimental Alzheimer's disease by targeting multiple pathophysiological mechanisms.
Daniela Giuliani, Alessandra Ottani, Davide Zaffe, Maria Galantucci, Flavio Strinati

Neurobiol Learn Mem· September 2013

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Modulation of the JAK/ERK/STAT signaling in melanocortin-induced inhibition of local and systemic responses to myocardial ischemia/reperfusion.
Alessandra Ottani, Maria Galantucci, Ettore Ardimento, Laura Neri, Fabrizio Canalini

Pharmacol Res· June 2013

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Up-regulation of the canonical Wnt-3A and Sonic hedgehog signaling underlies melanocortin-induced neurogenesis after cerebral ischemia.
Luca Spaccapelo, Maria Galantucci, Laura Neri, Miranda Contri, Roberto Pizzala, Alessandra Ottani

Eur J Pharmacol· May 2013

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Centrally acting leptin induces a resuscitating effect in haemorrhagic shock in rats.
Jerzy Jochem, Zbigniew Kalarus, Luca Spaccapelo, Fabrizio Canalini, Alessandra Ottani

Regul Pept· June 2012

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Melanocortins as potential therapeutic agents in severe hypoxic conditions.
Daniela Giuliani, Letteria Minutoli, Alessandra Ottani, Luca Spaccapelo, Alessandra Bitto

Front Neuroendocrinol· April 2012

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Protective effects of melanocortins on short-term changes in a rat model of traumatic brain injury*.
Alessandra Bitto, Francesca Polito, Natasha Irrera, Margherita Calò, Luca Spaccapelo, Alessandra Ottani

Crit Care Med· March 2012

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Molecular changes induced in rat liver by hemorrhage and effects of melanocortin treatment.
Caterina Lonati, Andrea Sordi, Daniela Giuliani, Luca Spaccapelo, Patrizia Leonardi, Alessandra Ottani

Anesthesiology· March 2012

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Melanocortin MC₄ receptor agonists counteract late inflammatory and apoptotic responses and improve neuronal functionality after cerebral ischemia.
Luca Spaccapelo, Alessandra Bitto, Maria Galantucci, Alessandra Ottani, Natasha Irrera

Eur J Pharmacol· November 2011

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Melanocortin 4 receptor activation protects against testicular ischemia-reperfusion injury by triggering the cholinergic antiinflammatory pathway.
Letteria Minutoli, Alessandra Bitto, Francesco Squadrito, Natasha Irrera, Mariagrazia Rinaldi, Alessandra Ottani

Endocrinology· October 2011

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Treatment of cerebral ischemia with melanocortins acting at MC4 receptors induces marked neurogenesis and long-lasting functional recovery.
Daniela Giuliani, Davide Zaffe, Alessandra Ottani, Luca Spaccapelo, Maria Galantucci

Acta Neuropathol· October 2011

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