Publications by authors named "Alessandro Alaimo"

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TRPM8 levels determine tumor vulnerability to channel agonists.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi

Mol Oncol· October 2025

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Germline-Somatic Liaison Dictates Cancer Subtypes via de novo Steroid Biosynthesis.
Paola Gasperini, Alessandro Alaimo, Blerta Stringa, Yoon-Mi Chung, Yari Ciani

Cancer Discov· October 2025

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Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer.
Dario De Felice, Alessandro Alaimo, Davide Bressan, Sacha Genovesi, Elisa Marmocchi

EMBO Rep· January 2025

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Sterile inflammation via TRPM8 RNA-dependent TLR3-NF-kB/IRF3 activation promotes antitumor immunity in prostate cancer.
Alessandro Alaimo, Sacha Genovesi, Nicole Annesi, Dario De Felice, Saurav Subedi

EMBO J· March 2024

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Rarγ -Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer.
Dario De Felice, Alessandro Alaimo, Davide Bressan, Sacha Genovesi, Elisa Marmocchi

bioRxiv· March 2024

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Intra-epithelial non-canonical Activin A signaling safeguards prostate progenitor quiescence.
Francesco Cambuli, Veronica Foletto, Alessandro Alaimo, Dario De Felice, Francesco Gandolfi

EMBO Rep· May 2022

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ETS-related gene (ERG) undermines genome stability in mouse prostate progenitors via Gsk3β dependent Nkx3.1 degradation.
Marco Lorenzoni, Dario De Felice, Giulia Beccaceci, Giorgia Di Donato, Veronica Foletto, Alessandro Alaimo

Cancer Lett· May 2022

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The Journal Club: Highlights on Recent Papers-1.
Francesc Rabanal, Mark S Johnson, Alessandro Alaimo, Victor M Bolanos-Garcia, Travis Beddoe

Biomolecules· January 2022

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Trpm8 Expression in Human and Mouse Castration Resistant Prostate Adenocarcinoma Paves the Way for the Preclinical Development of TRPM8-Based Targeted Therapies.
Sacha Genovesi, Riccardo Moro, Beatrice Vignoli, Dario De Felice, Marco Canossa, Alessandro Alaimo

Biomolecules· January 2022

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Tune the channel: TRPM8 targeting in prostate cancer.
Alessandro Alaimo, Dario De Felice, Sacha Genovesi, Marco Lorenzoni, Andrea Lunardi

Oncoscience· September 2021

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TRPM8 protein expression in hormone naïve local and lymph node metastatic prostate cancer.
Andrea Lunardi, Mattia Barbareschi, Francesco Giuseppe Carbone, Luca Morelli, Matteo Brunelli, Alessandro Alaimo

Pathologica· April 2021

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Magnolol and Honokiol: Two Natural Compounds with Similar Chemical Structure but Different Physicochemical and Stability Properties.
Iris Usach, Alessandro Alaimo, Juan Fernández, Alessandro Ambrosini, Sara Mocini

Pharmaceutics· February 2021

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Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors.
Alessandro Alaimo, Marco Lorenzoni, Paolo Ambrosino, Arianna Bertossi, Alessandra Bisio

Cell Death Dis· December 2020

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The Organoid Era Permits the Development of New Applications to Study Glioblastoma.
Francesco Andreatta, Giulia Beccaceci, Nicolò Fortuna, Martina Celotti, Dario De Felice, Alessandro Alaimo

Cancers (Basel)· November 2020

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Mechanosensitive Piezo Channels in Cancer: Focus on altered Calcium Signaling in Cancer Cells and in Tumor Progression.
Dario De Felice, Alessandro Alaimo

Cancers (Basel)· July 2020

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The Pivotal Role of TRP Channels in Homeostasis and Diseases throughout the Gastrointestinal Tract.
Alessandro Alaimo, Josep Rubert

Int J Mol Sci· October 2019

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Lack of correlation between surface expression and currents in epileptogenic AB-calmodulin binding domain Kv7.2 potassium channel mutants.
Alessandro Alaimo, Ainhoa Etxeberria, Juan Camilo Gómez-Posada, Carolina Gomis-Perez, Juncal Fernández-Orth

Channels (Austin)· August 2019

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Calmodulin: A Multitasking Protein in Kv7.2 Potassium Channel Functions.
Alessandro Alaimo, Alvaro Villarroel

Biomolecules· July 2018

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Calmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7.2 channels.
Alessandro Alaimo, Eider Nuñez, Paloma Aivar, Juncal Fernández-Orth, Carolina Gomis-Perez

Sci Rep· October 2017

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Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate.
Maria Virginia Soldovieri, Paolo Ambrosino, Ilaria Mosca, Michela De Maria, Edoardo Moretto, Alessandro Alaimo

Sci Rep· December 2016

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Uncoupling PIP2-calmodulin regulation of Kv7.2 channels by an assembly destabilizing epileptogenic mutation.
Araitz Alberdi, Carolina Gomis-Perez, Ganeko Bernardo-Seisdedos, Alessandro Alaimo, Covadonga Malo

J Cell Sci· November 2015

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Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin.
Paolo Ambrosino, Alessandro Alaimo, Silvia Bartollino, Laura Manocchio, Michela De Maria

Biochim Biophys Acta· September 2015

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An unconventional calmodulin-anchoring site within the AB module of Kv7.2 channels.
Carolina Gomis-Perez, Alessandro Alaimo, Juncal Fernandez-Orth, Araitz Alberdi, Paloma Aivar-Mateo

J Cell Sci· August 2015

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Clicked bis-PEG-peptide conjugates for studying calmodulin-Kv7.2 channel binding.
M Angeles Bonache, Alessandro Alaimo, Covadonga Malo, Oscar Millet, Alvaro Villarroel

Org Biomol Chem· November 2014

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The ever changing moods of calmodulin: how structural plasticity entails transductional adaptability.
Alvaro Villarroel, Maurizio Taglialatela, Ganeko Bernardo-Seisdedos, Alessandro Alaimo, Jon Agirre

J Mol Biol· July 2014

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