Publications by authors named "Alessandro Cignetti"

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Pegaspargase administration and tolerability in patients aged 55 years or older with acute lymphoblastic leukemia treated with the LAL1913 program. A subanalysis of the Campus ALL group.
Davide Lazzarotto, Anna Maria Testi, Matteo Fanin, Federico Mosna, Sabina Chiaretti, Alessandro Cignetti

Ann Hematol· November 2025

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Venetoclax plus hypomethylating agents as effective bridge therapy to allogeneic stem cell transplant in relapsed/refractory acute myeloid leukaemia: A subanalysis of the AVALON study.
Elisabetta Petracci, Francesca Pavesi, Luca Castagna, Patrizia Zappasodi, Cristina Papayannidis, Alessandro Cignetti

Br J Haematol· November 2025

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Outcomes of allogeneic stem cell transplant in adult Philadelphia negative acute lymphoblastic leukemia patients treated with the pediatric-inspired GIMEMA 1913 protocol. A Campus ALL study.
Gianluca Cavallaro, Davide Lazzarotto, Chiara Pavoni, Francesca Valsecchi, Anna Grassi, Alessandro Cignetti

Bone Marrow Transplant· September 2025

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Impact of Pre-Treatment Comorbidity Burden on Survival in Patients Receiving Venetoclax Plus Hypomethylating Agents.
Giovanni Marconi, Elisabetta Petracci, Giuseppe Lanzarone, Calogero Vetro, Maria Paola Martelli, Alessandro Cignetti

Am J Hematol· April 2025

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Outcome of 421 adult patients with Philadelphia-negative acute lymphoblastic leukemia treated under an intensive program inspired by the GIMEMA LAL1913 clinical trial: a Campus ALL study.
Davide Lazzarotto, Marco Cerrano, Cristina Papayannidis, Sabina Chiaretti, Federico Mosna, Alessandro Cignetti

Haematologica· January 2025

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Venetoclax Plus Intensified Chemoimmunotherapy as a Bridge to Allogeneic Stem Cell Transplantation in Richter Syndrome: Report of Two Cases.
Enrico Derenzini, Alessandro Cignetti, Valentina Tabanelli, Daniela Gottardi, Elvira Gerbino

Hematol Rep· December 2024

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SARS-CoV-2 vaccination in 361 non-transplanted patients with aplastic anemia and/or paroxysmal nocturnal hemoglobinuria.
Morag Griffin, Dirk-Jan Eikema, Inge Verheggen, Alexander Kulagin, Jennifer M-L Tjon, Alessandro Cignetti

Haematologica· January 2024

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Blinatumomab differentially modulates peripheral blood and bone marrow immune cell repertoire: A Campus ALL study.
Darina Ocadlikova, Federico Lussana, Nicola Fracchiolla, Massimiliano Bonifacio, Lidia Santoro, Alessandro Cignetti

Br J Haematol· November 2023

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Long telomeres at baseline and male sex are main determinants of telomere loss following chemotherapy exposure in lymphoma patients.
Enrico Derenzini, Angela Gueli, Alessandra Risso, Riccardo Bruna, Daniela Gottardi, Alessandro Cignetti

Hematol Oncol· August 2023

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Full chimaeric CAR.CIK from patients engrafted after allogeneic haematopoietic cell transplant: Feasibility, anti-leukaemic potential and alloreactivity across major human leukocyte antigen barriers.
Paola Circosta, Chiara Donini, Susanna Gallo, Lidia Giraudo, Loretta Gammaitoni, Alessandro Cignetti

Br J Haematol· January 2023

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Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-]pyridine Scaffold: SAR of the Aryloxyaryl Moiety.
Stefano Sainas, Marta Giorgis, Paola Circosta, Giulio Poli, Marta Alberti, Alessandro Cignetti

J Med Chem· October 2022

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Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia.
Mohammad Houshmand, Nicoletta Vitale, Francesca Orso, Alessandro Cignetti, Ivan Molineris

Cell Death Dis· June 2022

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Shedding Light on Targeting Chronic Myeloid Leukemia Stem Cells.
Mohammad Houshmand, Alireza Kazemi, Ali Anjam Najmedini, Muhammad Shahzad Ali, Valentina Gaidano, Alessandro Cignetti

J Clin Med· December 2021

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Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-]pyridine Scaffold: SAR of the Biphenyl Moiety.
Stefano Sainas, Marta Giorgis, Paola Circosta, Valentina Gaidano, Davide Bonanni, Alessandro Cignetti

J Med Chem· May 2021

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Prognostic Impact of Baseline Immunologic Profile in Aggressive B-cell non-Hodgkin's Lymphomas.
Safaa Ramadan, Giusy Ceparano, Alessandro Cignetti, Simona Sammassimo, Vincenzo Bagnardi

Mediterr J Hematol Infect Dis· March 2021

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Post-Transplant Cyclophosphamide and Tacrolimus-Mycophenolate Mofetil Combination Governs GVHD and Immunosuppression Need, Reducing Late Toxicities in Allogeneic Peripheral Blood Hematopoietic Cell Transplantation from HLA-Matched Donors.
Fabrizio Carnevale-Schianca, Daniela Caravelli, Susanna Gallo, Paolo Becco, Luca Paruzzo, Alessandro Cignetti

J Clin Med· March 2021

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Targeting Chronic Myeloid Leukemia Stem/Progenitor Cells Using Venetoclax-Loaded Immunoliposome.
Mohammad Houshmand, Francesca Garello, Rachele Stefania, Valentina Gaidano, Alessandro Cignetti

Cancers (Basel)· March 2021

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The Synergism between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid Leukemia.
Valentina Gaidano, Mohammad Houshmand, Nicoletta Vitale, Giovanna Carrà, Alessandro Morotti, Alessandro Cignetti

Cancers (Basel)· February 2021

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CPX-351 treatment in secondary acute myeloblastic leukemia is effective and improves the feasibility of allogeneic stem cell transplantation: results of the Italian compassionate use program.
Fabio Guolo, Luana Fianchi, Paola Minetto, Marino Clavio, Michele Gottardi, Alessandro Cignetti

Blood Cancer J· October 2020

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A Clinically Applicable Approach to the Classification of B-Cell Non-Hodgkin Lymphomas with Flow Cytometry and Machine Learning.
Valentina Gaidano, Valerio Tenace, Nathalie Santoro, Silvia Varvello, Alessandro Cignetti

Cancers (Basel)· June 2020

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Chronic myeloid leukemia stem cells.
Mohammad Houshmand, Giorgia Simonetti, Paola Circosta, Valentina Gaidano, Alessandro Cignetti

Leukemia· July 2019

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An Ig Transmembrane Domain Motif Improves the Function of TCRs Transduced in Human T Cells: Implications for Immunotherapy.
Luciana D'Apice, Fausta Cuccaro, Sonia Varriale, Deborah Cipria, Rossella Sartorius, Alessandro Cignetti

J Immunother· May 2019

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Correction to Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors.
Stefano Sainas, Agnese C Pippione, Elisa Lupino, Marta Giorgis, Paola Circosta, Alessandro Cignetti

J Med Chem· February 2019

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Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors.
Stefano Sainas, Agnese C Pippione, Elisa Lupino, Marta Giorgis, Paola Circosta, Alessandro Cignetti

J Med Chem· July 2018

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Survivin-peptide vaccination elicits immune response after allogeneic nonmyeloablative transplantation: a safe strategy to enhance the graft versus tumor effect.
Paola Circosta, Katia Vitaggio, Angela Rita Elia, Maja Todorovic, Dario Sangiolo, Alessandro Cignetti

Immunotherapy· July 2018

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